Use of probiotic microorganisms to limit skin irritation

• US 8,481,299 B2
• Filed: 03/04/2010
• Issued: 07/09/2013
• Est. Priority Date: 03/04/2009
• Status: Active Grant

• Current Assignee: L'Oreal SA, Societe des Produits Nestle SA (Nestle SA)
• Original Assignee: L'Oreal SA, Nestec SA (Nestle SA)
• Inventors: Gueniche, Audrey
• Primary Examiner(s): Ford, Allison
• Assistant Examiner(s): Pyla, Yvonne
• Application Number:
  US12/717,438
• Publication Number:
  US 20100226892A1
• Time in Patent Office: 1,223 Days
• Field of Search: None
• US Class Current: 435/252.9
• CPC Class Codes: A61K 2800/92 Oral administration
• CPC Class Codes: A61K 8/99 from microorganisms other than algae or fungi, e.g. protozoa or bacteria
• CPC Class Codes: A61P 17/00 Drugs for dermatological disorders
• CPC Class Codes: A61P 17/02 for treating wounds, ulcers, burns, scars, keloids, or the like
• CPC Class Codes: A61P 17/16 Emollients or protectives, e.g. against radiation
• CPC Class Codes: A61Q 19/00 Preparations for care of the skin
• CPC Class Codes: A61Q 19/005 Preparations for sensitive skin

Abstract

Disclosed are methods directed to the cosmetic use of an effective amount of at least one probiotic microorganism especially from the genus Lactobacillus sp. and/or Bifidobacterium sp., of a fraction thereof and/or of a metabolite thereof, as an active agent for limiting, preventing or treating skin irritation and/or irritative skin disorders.

Claims

1. A cosmetic method for treating a non allergic irritant contact dermatitis of an individual in need thereof, the method comprising:

administering to said individual an active agent comprising an effective amount of at least one;

probiotic microorganism selected from the genus Lactobacillus sp.,

a fraction of a probiotic microorganism selected from the genus Lactobacillus sp., and

a metabolite of a probiotic microorganism selected from the Lactobacillus sp.

2. The method according to claim 1, wherein the non allergic irritant contact dermatitis is induced by at least one condition selected from the action of:

chemical products, compounds capable of provoking a non allergic irritant contact dermatitis, temperature, climate, atmospheric pollution, and friction.

3. The method according to claim 2, wherein said probiotic microorganism is intended for preventing and/or reducing the irritant effect of a cosmetic or dermatological composition comprising one or more compounds capable of provoking a non allergic irritant contact dermatitis.

4. The method according to claim 1, wherein the microorganism is selected from the group consisting of Lactobacillus johnsonii, Lactobacillus reuteri, Lactobacillus rhamnosus, Lactobacillus paracasei, Lactobacillus casei, and mixtures thereof.

5. The method according to claim 1, wherein the microorganism is selected from the group consisting of Lactobacillus johnsonii, and Lactobacillus paracasei, deposited respectively under the following designations:

CNCM I-1225, and CNCM I-2116.

6. The method according to claim 1, wherein the microorganism is Lactobacillus paracasei.

7. The method according to claim 1, wherein the microorganism is Lactobacillus paracasei CNCM I-2116.

8. The method according to claim 1, wherein said microorganism is present in a proportion of 0.0001 to 20% by weight relative to a total weight of a composition comprising said microorganism.

9. The method according to claim 1, wherein said microorganism is administered topically or orally.

10. A cosmetic treatment method for treating non allergic irritant contact dermatitis of an individual in need thereof, the method comprising administering to the individual an effective amount of at least one microorganism belonging to the species Lactobacillus paracasei, a fraction of a microorganism belonging to the species Lactobacillus paracasei, and a metabolite of a microorganism belonging to the species Lactobacillus paracasei.