Anti-adherent formulation including a quaternary ammonium compound and a fatty alcohol

• US 8,481,480 B1
• Filed: 04/30/2012
• Issued: 07/09/2013
• Est. Priority Date: 04/30/2012
• Status: Active Grant

• Current Assignee: Kimberly-Clark Worldwide Incorporated (Kimberly-Clark Corporation)
• Original Assignee: Kimberly-Clark Worldwide Incorporated (Kimberly-Clark Corporation)
• Inventors: Wolff, Kelly Laura, Cunningham, Corey T., Hoffman, Douglas R., Wenzel, Scott W., Lam, Uyen T.
• Primary Examiner(s): Tsang, Cecilia J
• Assistant Examiner(s): Miknis, Zachary J
• Application Number:
  US13/460,284
• Time in Patent Office: 435 Days
• Field of Search: None
• US Class Current: 514/1.1
• CPC Class Codes: A61K 8/0208 Tissues; Wipes; Patches
• CPC Class Codes: A61K 8/342 Alcohols having more than seven atoms in an unbroken chain
• CPC Class Codes: A61K 8/416 Quaternary ammonium compounds A61K8/35 takes precedence
• CPC Class Codes: A61K 8/65 Collagen; Gelatin; Keratin; Derivatives or degradation products thereof
• CPC Class Codes: A61K 8/73 Polysaccharides
• CPC Class Codes: A61K 8/8182 Copolymers of vinyl-pyrrolidones. Compositions of derivatives of such polymers
• CPC Class Codes: A61K 8/88 Polyamides
• CPC Class Codes: A61K 8/898 containing nitrogen, e.g. amodimethicone, trimethyl silyl amodimethicone or dimethicone propyl PG-betaine
• CPC Class Codes: A61P 17/00 Drugs for dermatological disorders
• CPC Class Codes: A61Q 17/00 Barrier preparations; Preparations brought into direct contact with the skin for affording protection against external influences, e.g. sunlight, X-rays or other harmful rays, corrosive materials, bacteria or insect stings

Abstract

Formulations having anti-adherent properties are disclosed herein. The anti-adherent formulation described herein acts to prevent the adherence of menses and/or fecal material to the skin in the labial and perianal regions during and after menstruation or defecation, respectively. The anti-adherent formulation contains a carrier, from about 0.1% by weight to about 10.0% by weight of a quaternary ammonium compound, and from about 0.5% by weight to about 10.0% by weight of a fatty alcohol. The anti-adherent formulation may be applied to the targeted surface either directly, in liquid form, such as by a spray bottle or similar packaging capable of delivering a liquid formulation in a relatively uniform amount over the full surface to be covered. Alternatively, the formulation may be applied to the targeted surface by a “wet” wipe or wiper.

Claims

1. An anti-adherent formulation having anti-adherent activity comprising:

a carrier,

from about 0.1% by weight to about 10% by weight of a quaternary ammonium compound;

and

from about 0.5% by weight to about 10% by weight of a fatty alcohol;

wherein the anti-adeherent formulation has menses leave-on percentage of less than about 7.4%.

2. The anti-adherent formulation of claim 1 wherein the quaternary ammonium compound is selected from behentrimonium methosulfate, behentrimonium chloride, behentrimoniumsulfate, cetrimonium chloride, stearamidopropyl ethyldimonium ethosulfate, C_10-40 isoalkylamidopropylethyldimonium ethosulfate, cocotrimonium chloride, quaternium-79 hydrolyzed collagen, quaternium-80, quaternium-88, quaternium-95, polyquaternium-68, polyquaternium-78, polyquaternium-81, polyquaternium-82, and combinations thereof.

3. The anti-adherent formulation of claim 2 wherein the quaternary ammonium compound is selected from behentrimonium methosulfate, behentrimonium chloride, and quaternium-80.

4. The formulation of claim 1 wherein the fatty alcohol is selected from lauryl alcohol, myristyl alcohol, cetyl alcohol, cetearyl alcohol, stearyl alcohol, arachidyl alcohol, behenyl alcohol, and combinations thereof.

5. The anti-adherent formulation of claim 4 wherein the fatty alcohol has between 12 and 22 carbon atoms per molecule.

6. The anti-adherent formulation of claim 4 wherein the fatty alcohol comprises cetearyl alcohol.

7. The anti-adherent formulation of claim 1 further comprising from about 0.5% to about 5.0% by weight polyol.

8. The anti-adherent formulation of claim 1 wherein the formulation includes from about 0.25% by weight to about 7.0% by weight of the quaternary ammonium compound.

9. The anti-adherent formulation of claim 1 wherein the carrier is water, and wherein the anti-adherent formulation contains between about 65% and about 99% by weight of the carrier.

10. A wet wipe comprising:

a wipe substrate; and

a liquid formulation containing;

a carrier,

from about 0.1% by weight to about 10.0% by weight of a quaternary ammonium compound; and

from about 0.5% by weight to about 10.0% by weight of a fatty alcohol;

wherein the liquid formulation has menses leave-on percentage of less than about 7.4%.

11. The wet wipe of claim 10 wherein the quaternary ammonium compound is selected from behentrimonium methosulfate, behentrimonium chloride, behentrimoniumsulfate, cetrimonium chloride, stearamidopropyl ethyldimonium ethosulfate, C_10-40 isoalkylamidopropylethyldimonium ethosulfate, cocotrimonium chloride, quaternium-79 hydrolyzed collagen, quaternium-80, quaternium-88, quaternium-95, polyquaternium-68, polyquaternium-78, polyquaternium-81, polyquaternium-82, and combinations thereof.

12. The wet wipe of claim 11 wherein the quaternary ammonium compound is selected from behentrimonium methosulfate, behentrimonium chloride, and quaternium-80.

13. The wet wipe of claim 10 wherein the fatty alcohol is selected from lauryl alcohol, myristyl alcohol, cetyl alcohol, cetearyl alcohol, stearyl alcohol, arachidyl alcohol, behenyl alcohol, and combinations thereof.

14. The wet wipe of claim 13 wherein the fatty alcohol comprises cetearyl alcohol.

15. The wet wipe of claim 10 wherein the formulation includes from about 0.25% by weight to about 7.0% by weight of the quaternary ammonium compound.

16. The wet wipe of claim 10 wherein the carrier is water, and wherein the liquid formulation contains between about 65% and about 99% by weight of the carrier.

17. The wet wipe of claim 10 further comprising from about 0.5% to about 5.0% by weight polyol.