Synthesis of epothilones, intermediates thereto, analogues and uses thereof
First Claim
Patent Images
1. A method of stabilizing microtubules in a subject, the method comprising steps of:
- administering to a subject in need thereof a composition comprising a compound having the structure;
1 Assignment
0 Petitions
Accused Products
Abstract
The present invention provides convergent processes for preparing epothilone A and B, desoxyepothilones A and B, and analogues thereof. Also provided are analogues related to epothilone A and B and intermediates useful for preparing same. The present invention further provides novel compositions based on analogues of the epothilones and methods for the treatment of cancer and cancer which has developed a multidrug-resistant phenotype.
-
Citations
6 Claims
-
1. A method of stabilizing microtubules in a subject, the method comprising steps of:
administering to a subject in need thereof a composition comprising a compound having the structure; - View Dependent Claims (2, 3, 4, 5, 6)
Specification