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Mutant smoothened and methods of using the same

  • US 8,481,680 B2
  • Filed: 10/05/2011
  • Issued: 07/09/2013
  • Est. Priority Date: 10/05/2010
  • Status: Active Grant
First Claim
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1. An isolated mutant SMO protein comprising the amino acid sequence of SEQ ID NO:

  • 2, wherein said amino acid sequence comprises alanine (A) or lysine (K) at amino acid 518.

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