×

Variation analysis for multiple templates on a solid support

  • US 8,483,969 B2
  • Filed: 09/17/2010
  • Issued: 07/09/2013
  • Est. Priority Date: 09/17/2010
  • Status: Active Grant
First Claim
Patent Images

1. A method of detecting molecules, said method comprising the steps of:

  • (a) providing a solid support comprising molecules associated with a site on the solid support such that the molecules are detected in aggregate during a detection step, wherein the site comprises at least two different types of molecules;

    (b) detecting a signal corresponding to the aggregate of molecules at the site;

    (c) providing an initial estimate of the amount of signal corresponding to different types of molecules at the site;

    (d) calculating the amount of signal corresponding to different types of molecules at the site using the initial estimate, thereby obtaining a signal estimate; and

    (e) iteratively updating the initial estimate until the signal estimates converge, thereby detecting molecules associated with the site.

View all claims
  • 1 Assignment
Timeline View
Assignment View
    ×
    ×