Method of calibrating a biometric device

• US 8,485,016 B2
• Filed: 06/11/2007
• Issued: 07/16/2013
• Est. Priority Date: 06/12/2006
• Status: Active Grant

• Current Assignee: Amir Moezzi, Trefford Simpson
• Original Assignee: Amir Moezzi, Trefford Simpson
• Inventors: Simpson, Trefford, Moezzi, Amir
• Primary Examiner(s): Raevis, Robert R
• Application Number:
  US12/308,053
• Publication Number:
  US 20090163796A1
• Time in Patent Office: 2,227 Days
• Field of Search: None
• US Class Current: 73/1.79
• CPC Class Codes: A61B 2560/0223 of calibration, e.g. protocols for calibrating sensors
• CPC Class Codes: A61B 5/0059 using light, e.g. diagnosis by transillumination, diascopy, fluorescence A61B5/0093, A61B5/1455, A61B5/02416 and A61B5/0261 take precedence
• CPC Class Codes: A61B 5/0066 Optical coherence imaging
• CPC Class Codes: A61B 5/1075 for measuring dimensions by non-invasive methods, e.g. for determining thickness of tissue layer A61B8/0858 takes precedence
• CPC Class Codes: A61B 8/10 Eye inspection

Abstract

A method of calibrating a biometric device useful to measure a target dimension of a physiological tissue is provided comprising the steps of: measuring the target dimension of at least two samples of a reference material with the device to provide an actual output, wherein the reference material possesses at least one property of the tissue required for the function of the device and wherein each of the samples has a known target dimension; calculating a calibration equation based on the actual output of the device and the known target dimensions of the samples; and adjusting the actual output of the device according to the calibration equation to yield a corrected output. The calibration method provides a means of obtaining accurate tissue measurements. Also provided is a method of using a biometric device to measure a target dimension of a physiological tissue which incorporates calibration.

Claims

1. A method of calibrating an optical biometric device useful to measure a physical characteristic of a physiological tissue comprising:

(i) measuring the physical characteristic of at least two samples of a reference material selected from the group consisting of;

plastic, glass, fluid and gas with the optical biometric device to provide an actual output, wherein the reference material possesses at least one property of the physiological tissue which is required for the function of the optical biometric device and wherein the physical characteristic of each of the samples is pre-measured,

(ii) calculating a calibration equation based on the actual output of the optical biometric device and the pre-measured physical characteristic of the samples; and

(iii) adjusting the actual output of the optical biometric device according to the calibration equation to yield a corrected output.

2. A method as defined in claim 1, wherein the optical biometric device is selected from the group consisting of:

pachometers, optical coherence tomographers (OCT'"'"'s), scanning slit imaging devices, confocal microscopes and Scheimpflug devices.

3. A method as defined in claim 1, wherein the reference material possesses a refractive index equal to the refractive index (RI) of the target tissue.

4. A method as defined in claim 1, wherein the physiological tissue is selected from the group consisting of epidermal tissue, connective tissue, muscle tissue, vascular tissue, nervous tissue and ocular tissue.

5. A method as defined in claim 4, wherein the ocular tissue is selected from the group consisting of corneal tissue, retinal tissue, lens tissue, aqueous humour and vitreous humour.

6. A method as defined in claim 1, wherein the physical characteristic is selected from the group consisting of:

thickness, length, curvature, and shape.

7. A method as defined in claim 1, wherein the calibration equation is determined using linear regression analysis of the known physical characteristic and the actual output of the device.

8. A method as defined in claim 1, including the additional step of cross-calibrating the optical biometric device with a second biometric device which functions differently than the optical biometric device, wherein the reference material possesses properties of the target tissue required for the function of each of the optical biometric devices and the second biometric device.

9. A method as defined in claim 8, wherein the second biometric device is a non-optical device, and wherein the reference material has a refractive index and an additional non-optical characteristic of the target material that is required for the function of the second biometric device.

10. A method of measuring a physical characteristic of a physiological tissue using an optical biometric device comprising the steps of:

(i) measuring the physical characteristic of at least two samples of a reference material selected from the group consisting of;

plastic, glass, fluid and gas with the optical biometric device to provide an actual output, wherein the reference material possesses at least one property of the tissue which is required for the function of the optical biometric device and wherein the physical characteristic of each of the samples is pre-measured;

(ii) calculating a calibration equation based on the actual output of the optical biometric device and the pre-measured physical characteristic of the samples;

(iii) adjusting the actual output of the optical biometric device according to the calibration equation to yield a corrected output; and

(iv) measuring the physical characteristic of the tissue with the optical biometric device, wherein the measured physical characteristic is corrected according to the calibration equation.

11. A method as defined in claim 10, wherein the reference material possesses a refractive index equal to the refractive index (RI) of the target tissue.