System and method for monitoring or treating nervous system disorders
First Claim
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1. An implantable device for implantation in a head of a patient, the device comprising:
- a biocompatible housing adapted to be implanted beneath a patient'"'"'s scalp;
a cardiac monitoring element, the cardiac monitoring element adapted to sense cardiac activity to generate a cardiac signal;
a brain monitoring element operatively coupled to the housing, the brain monitoring element adapted to sense brain activity to generate a brain signal; and
a processor at least partially housed within the housing, the processor configured to(a) receive the cardiac signal from the cardiac monitoring element,(b) identify one or more cardiac events in the cardiac signal,(c) receive the brain signal from the brain monitoring element,(d) identify one or more neurological events in the brain signal, and(e) indicate a relationship between the neurological events and the cardiac events;
wherein the processor is further configured to perform the following;
(a) for each of the one or more identified neurological events, determine whether the neurological event is within a specified time period of one of the one or more identified cardiac events; and
(b) for each of the one or more identified cardiac events, determine whether the cardiac event is within a specified time period of one of the one or more identified neurological events.
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Abstract
An implantable neurostimulator device for implantation in a head of a patient includes a housing adapted to be implanted beneath a patient'"'"'s scalp, and a cardiac monitoring element, a brain monitoring element, and a processor. The processor is configured to receive a cardiac signal from the cardiac monitoring element, identify cardiac events in the cardiac signal, receive a brain signal from the brain monitoring element, identify neurological events in the brain signal, and indicate a relationship between the neurological events and the cardiac events.
205 Citations
84 Claims
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1. An implantable device for implantation in a head of a patient, the device comprising:
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a biocompatible housing adapted to be implanted beneath a patient'"'"'s scalp; a cardiac monitoring element, the cardiac monitoring element adapted to sense cardiac activity to generate a cardiac signal; a brain monitoring element operatively coupled to the housing, the brain monitoring element adapted to sense brain activity to generate a brain signal; and a processor at least partially housed within the housing, the processor configured to (a) receive the cardiac signal from the cardiac monitoring element, (b) identify one or more cardiac events in the cardiac signal, (c) receive the brain signal from the brain monitoring element, (d) identify one or more neurological events in the brain signal, and (e) indicate a relationship between the neurological events and the cardiac events; wherein the processor is further configured to perform the following; (a) for each of the one or more identified neurological events, determine whether the neurological event is within a specified time period of one of the one or more identified cardiac events; and (b) for each of the one or more identified cardiac events, determine whether the cardiac event is within a specified time period of one of the one or more identified neurological events. - View Dependent Claims (2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 16, 17, 18, 19, 20, 21, 22, 23, 24, 25, 26, 27, 28, 29, 30, 31, 32, 33, 34, 35, 36, 37, 38, 39, 40, 41, 42, 43, 44, 45, 46, 47, 51, 52, 53, 54, 55, 56, 57, 58, 59, 60, 61, 62, 63)
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48. An implantable device for implantation in a head of a patient, the device comprising:
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a biocompatible housing adapted to be implanted beneath a patient'"'"'s scalp; a cardiac monitoring element, the cardiac monitoring element adapted to sense cardiac activity to generate a cardiac signal; a brain monitoring element operatively coupled to the housing, the brain monitoring element adapted to sense brain activity to generate a brain signal; and a processor at least partially housed within the housing, the processor configured to (a) receive the cardiac signal from the cardiac monitoring element, (b) identify one or more cardiac events in the cardiac signal, (c) receive the brain signal from the brain monitoring element, (d) identify one or more neurological events in the brain signal, and (e) indicate a relationship between the neurological events and the cardiac events; wherein the processor is further configured to indicate a relationship between the neurological events and the cardiac events by performing the following; (a) categorizing the neurological event as cardiac matched when there is a cardiac event in close temporal relationship with the neurological event; and (b) computing a rate of concordance between the neurological events and the cardiac events based on a number of cardiac matched neurological events. - View Dependent Claims (49, 50)
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64. An implantable system comprising:
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a biocompatible housing adapted to be implanted beneath a patient'"'"'s scalp; a cardiac monitoring element adapted to sense cardiac activity and generate a cardiac signal; a brain monitoring element adapted to sense brain activity and generate a brain signal; and a processor at least partially housed within the housing, the processor being configured to (a) receive the cardiac signal from the cardiac monitoring element and detect one or more cardiac events in the cardiac signal, (b) receive the brain signal from the brain monitoring element and detect one or more neurological events in the brain signal, and (c) indicate a relationship between the neurological events and the cardiac events, wherein the processor is further configured to enable a cardiac event detection algorithm to detect neurological events when the relationship between the neurological events and the cardiac events indicates a rate of concordance between the neurological events and the cardiac events that exceeds a threshold value. - View Dependent Claims (65, 66, 67, 68, 69, 70)
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71. An implantable device for implantation in a head of a patient, the device comprising:
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a biocompatible housing adapted to be implanted beneath a patient'"'"'s scalp; a cardiac monitoring element, the cardiac monitoring element adapted to sense cardiac activity to generate a cardiac signal; a brain monitoring element operatively coupled to the housing, the brain monitoring element adapted to sense brain activity to generate a brain signal; and a processor at least partially housed within the housing, the processor configured to receive the cardiac signal from the cardiac monitoring element, identify a cardiac event in the cardiac signal, receive the brain signal from the brain monitoring element, identify a neurological event in the brain signal, and determine whether the cardiac event and the neurological event are within a specified time period of each other. - View Dependent Claims (72, 73, 74, 75, 76, 77, 78, 79, 80, 81, 82, 83, 84)
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Specification