Radioactive emission detector equipped with a position tracking system and utilization thereof with medical systems and in medical procedures

• US 8,489,176 B1
• Filed: 08/21/2000
• Issued: 07/16/2013
• Est. Priority Date: 08/21/2000
• Status: Active Grant

• Current Assignee: Spectrum Dynamics Medical Ltd
• Original Assignee: Spectrum Dynamics LLC
• Inventors: Ben-David, Gal, Zilberstien, Yoel, Kimchy, Yoav
• Primary Examiner(s): Jung, Unsu
• Assistant Examiner(s): SANTOS RODRIGUEZ, JOSEPH M
• Application Number:
  US09/641,973
• Time in Patent Office: 4,712 Days
• Field of Search: 600/407, 600/410, 600/411, 600/413, 600/414, 600/415, 600/417, 600/420, 600/431, 600425-429, 600/436, 600/424, 600/3, 606/130, 606/120, 702/152, 378/21
• US Class Current: 600/436
• CPC Class Codes: A61B 6/4258 for detecting non x-ray radiation, e.g. gamma radiation A61B6/037 takes precedence
• CPC Class Codes: A61F 2/04 Hollow or tubular parts of organs, e.g. bladders, tracheae, bronchi or bile ducts A61F2/18, A61F2/20 take precedence; devices, other than stent-grafts, providing patency to, or preventing collapsing of, tubular structures of the body other than stent-grafts, e.g. stents A61F2/82; instruments specially adapted for placement or removal of stents or stent-grafts A61F2/95
• CPC Class Codes: G01T 1/1603 with a combination of at least two different types of detector see provisionally also G01T1/16
• CPC Class Codes: G01T 1/161 Applications in the field of nuclear medicine, e.g. in vivo counting apparatus for radiation diagnosis A61B6/00

Abstract

A system for calculating a position of a radioactivity emitting source in a system-of-coordinates, the system comprising (a) a radioactive emission detector; (b) a position tracking system being connected to and/or communicating with the radioactive emission detector; and (c) a data processor being designed and configured for receiving data inputs from the position tracking system and from the radioactive emission detector and for calculating the position of the radioactivity emitting source in the system-of-coordinates.

Claims

1. A device for obtaining a distribution of a radioactivity emitting source in a system-of-coordinates, the device comprising:

(a) a radioactive emission detector for imaging a three-dimensional space comprising the radioactivity emitting source;

(b) a positioning instrument configured for carrying said radioactive emission detector to perform a plurality of radioactivity measurements of a radioactivity emitting source from a plurality of locations and directions;

(c) a position tracking device which monitors a position of said radioactive emission detector in relation to said three-dimensional space; and

(d) a data processor which reconstructs a three dimensional (3D) image of the radioactivity emitting source from a plurality of said radioactivity measurements with a varying spatial resolution and obtains a positional distribution of said radioactive emitting source using measurements of a same area from multiple locations having different resolution according to said position.

2. The device of claim 1, wherein said position tracking device is selected from the group consisting of an articulated arm position tracking device, an accelerometers based position tracking device, a potentiometers based position tracking device, a sound wave based position tracking device, a radio frequency based position tracking device, an electromagnetic field based position tracking device, and an optically based position tracking device.

3. The device of claim 1, wherein said radioactive emission detector is configured for free-hand scanning, and whose position is monitored by said position tracking device in a first system-of-coordinates, further comprising:

a surgical instrument whose position is monitored by an additional position tracking device for tracking a position of said surgical instrument in a second system-of-coordinates and at least one data processor being designed and configured for receiving data inputs from said position tracking device, said radioactive emission detector and said additional position tracking device and for calculating the position of the surgical instrument and the radiopharmaceutical uptaking portion of the body component in a common system-of-coordinates.

4. The device of claim 3, wherein said first position tracking device and said second position tracking device are a single position tracking device.

5. The device of claim 3, further comprising an image presentation device which serves for visual co-presentation of the position of said surgical instrument and the radiopharmaceutical uptaking portion of the body component.

6. The device of claim 3, wherein said surgical instrument is selected from the group consisting of laser probe, cardiac catheter, angioplastic catheter, endoscopic probe, biopsy needle, ultrasonic probe, fiber optic scopes, aspiration tubes, laparoscopy probe, thermal probe and suction/irrigation probe.

7. The device of claim 1, wherein said position is a positional change.

8. The device of claim 1, wherein said detector performs said plurality of radioactivity measurements in different resolutions.

9. The device of claim 1, wherein said data processor reconstructs said image according to radioactivity measurements having different resolutions.

10. The device of claim 1, wherein said detector performs said plurality of radioactivity measurements from different angles and distances.

11. The device of claim 1, wherein said spatial resolution is higher for radioactivity measurements as the detector approaches the radiation source.

12. A method for reconstructing a radiopharmaceutical uptaking portion of a body component within a subject, the method comprising:

(a) providing radioactive emission detector supported by a positioning instrument;

(b) using said radioactive emission detector for performing a plurality of radioactivity measurements of a radiopharmaceutical uptaking portion from a plurality of locations and directions;

(c) receiving data inputs from said radioactive emission detector; and

(d) reconstructing according to said data inputs a three dimensional (3D) model of said radiopharmaceutical uptaking portion;

wherein said performing comprises monitoring a position of said radioactive emission detector in relation to said radiopharmaceutical uptaking portion and calculating a spatial 3D resolution of said three dimensional model, and

wherein said three dimensional model is reconstructed using measurements of a same area from multiple locations having different spatial resolution according to said locations.

13. The method for claim 12, wherein said radioactive emission detector communicates with an image presentation device which serves for visual presentation of said radiopharmaceutical uptaking portion.

14. The method of claim 12, and further including monitoring changes of the radiopharmaceutical uptaking portion of the body component as a function of time, responsive to treatment.

15. The method of claim 12, and further including monitoring changes of the radiopharmaceutical uptaking portion of the body component as a function of time, responsive to treatment, selected from the group consisting of chemotherapy, brachytherapy, cryogenic ablation, radio frequency ablation, ultrasound ablation, and laser ablation.

16. The method of claim 12, wherein said performing comprises:

(a) monitoring a position of said radioactive emission detector using a first position tracking device, thus obtaining a position of the radiopharmaceutical uptaking portion of the body component in a first system-of-coordinates;

(b) monitoring a position of a surgical instrument using a second position tracking device, thus tracking a position of said surgical instrument in a second system-of-coordinates while performing an intrabody surgical procedure; and

(c) receiving data inputs from said first position tracking device, said radioactive emission detector and said second position tracking device and calculating the position of the surgical instrument and the radiopharmaceutical uptaking portion of the body component in a common system-of-coordinates while performing the intrabody surgical procedure.

17. The method of claim 16, further comprising co-presenting the position of said surgical instrument and the radiopharmaceutical uptaking portion of the body component.

18. The method of claim 12, wherein said monitoring a position of said radioactive emission detector comprises moving said radioactive emission detector in six degrees of freedom.

19. The method of claim 12, wherein said monitoring a position of said radioactive emission detector comprises continuously moving said radioactive emission detector during said performing.

20. The method of claim 12, wherein said monitoring a position of said radioactive emission detector comprises switching between a plurality of collimators to allow performing said plurality of radioactivity measurements at said plurality of spatial resolutions from a common location.

21. The method of claim 12, further comprising tracking positional changes of said positioning instrument in relation to said radioactivity emitting source, said performing is carried out with respect to said tracking.

22. A method for scanning a radioactivity emitting source in a three dimensional space comprising a radioactivity emitting source, comprising:

using a positioning instrument for carrying a radioactive emission detector to perform a scan from a plurality of directions at multiple sites around said three dimensional space while changing a position of said radioactive emission detector in at least three degrees of freedom to image the radioactivity emitting source;

monitoring a positional change of said radioactive emission detector in relation to the three dimensional space during said scan;

computing a spatial 3D resolution change according to said positional change, using measurements with a varying spatial resolution of a same area from multiple locations at different sensitivities; and

generating a three dimensional (3D) image of said three dimensional space according to said spatial 3D resolution change.

23. The method of claim 22, wherein said using comprises using an articulated arm for carrying said radioactive emission detector.

24. The method of claim 22, wherein said using comprises using a gantry for carrying said radioactive emission detector instrument.

25. The method of claim 22, wherein said scanning is performed from anterior, inferior, and lateral positions around the three dimensional space.

26. The method of claim 22, wherein said changing comprises changing said position in at least four degrees.

27. The method of claim 22, wherein said changing comprises changing said position in at least five degrees.