Methods and devices for orthovoltage ocular radiotherapy and treatment planning
First Claim
1. A treatment planning method for treating a lesion at or adjacent to the retina of an eye of a patient, comprising:
- (a) determining, based on known spectral and intensity characteristics of a source beam along at least two treatment beam paths from a source of a collimated x-radiation beam and from coordinates of the lesion in an aligned patient-eye position, a total treatment time for irradiation along the beam paths that is effective to produce a desired radiation dose at the lesion;
(b) determining, based on known spectral and intensity characteristics of the source beam along the beam paths and from coordinates of the optic nerve in the aligned patient-eye position, an extent and duration of eye movement, away from the aligned patient-eye position in a direction that moves the patient'"'"'s optic nerve toward the irradiation beam, that will be allowed during treatment, while maintaining a radiation dose at the patient optic nerve below a predetermined dose level; and
(c) directing the source, based on the determined treatment time and the determined extent and duration of eye movement, to emit the x-radiation beam to deliver the desired radiation to the lesion.
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Accused Products
Abstract
A method, code and system for planning the treatment a lesion on or adjacent to the retina of an eye of a patient are disclosed. There is first established at least two beam paths along which x-radiation is to be directed at the retinal lesion. Based on the known spectral and intensity characteristics of the beam, a total treatment time for irradiation along each beam paths is determined. From the coordinates of the optic nerve in the aligned eye position, there is determined the extent and duration of eye movement away from the aligned patient-eye position in a direction that moves the patient'"'"'s optic nerve toward the irradiation beam that will be allowed during treatment, while still maintaining the radiation dose at the patient optic nerve below a predetermined dose level.
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Citations
20 Claims
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1. A treatment planning method for treating a lesion at or adjacent to the retina of an eye of a patient, comprising:
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(a) determining, based on known spectral and intensity characteristics of a source beam along at least two treatment beam paths from a source of a collimated x-radiation beam and from coordinates of the lesion in an aligned patient-eye position, a total treatment time for irradiation along the beam paths that is effective to produce a desired radiation dose at the lesion; (b) determining, based on known spectral and intensity characteristics of the source beam along the beam paths and from coordinates of the optic nerve in the aligned patient-eye position, an extent and duration of eye movement, away from the aligned patient-eye position in a direction that moves the patient'"'"'s optic nerve toward the irradiation beam, that will be allowed during treatment, while maintaining a radiation dose at the patient optic nerve below a predetermined dose level; and (c) directing the source, based on the determined treatment time and the determined extent and duration of eye movement, to emit the x-radiation beam to deliver the desired radiation to the lesion. - View Dependent Claims (2, 3, 4, 5, 6, 7, 8, 9, 10)
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11. Non-transitory machine-readable medium which operates with a computer to execute machine-readable instructions for performing the steps in a treatment planning method for treating a lesion at or adjacent to the retina of an eye of a patient, by directing X-radiation at the lesion in a patient'"'"'s eye, based on an aligned patient-eye position, along at least two treatment beam paths from a source of a collimated x-radiation beam, comprising:
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(a) determining, based on known spectral and intensity characteristics of a source beam along the treatment beam paths and from coordinates of the lesion in the aligned patient-eye position, a total treatment time for irradiation along the beam paths that is effective to produce a desired radiation dose at the lesion; and (b) determining, based on known spectral and intensity characteristics of the source beam along the beam paths and from coordinates of the optic nerve in the aligned patient-eye position, an extent and duration of eye movement, away from the aligned patient-eye position in a direction that moves the patient'"'"'s optic nerve toward the irradiation beam, that will be allowed during treatment, while maintaining the radiation dose at the patient optic nerve below a predetermined dose level. - View Dependent Claims (12, 13, 14, 15)
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16. A system for planning a treatment for a lesion on or adjacent to the retina of an eye of a patient, by directing a radiation beam at the lesion in a patient'"'"'s eye, comprising:
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(a) a device for aligning the patient eye, (b) a processor configured to receive coordinates of an aligned patient-eye position in an external coordinate system, and that stores information effective for determining, from the received coordinates, coordinates of the lesion and optic nerve in the patient eye, and (c) a machine-readable medium which operates with the processor to execute machine-readable instructions for performing the steps of; (i) determining, based on known spectral and intensity characteristics of a source beam along established beam paths, directed from a source of a collimated x-radiation beam at the lesion, and from the coordinates of the lesion in the aligned patient-eye position, a total treatment time for irradiation along the beam paths that is effective to produce a desired radiation dose at the lesion, and (ii) determining, based on known spectral and intensity characteristics of the source beam along the established beam paths and from the coordinates of the optic nerve in the aligned patient-eye position, the extent and duration of eye movement, away from the aligned patient-eye position in a direction that moves the patient'"'"'s optic nerve toward the irradiation beam, that will be allowed during treatment while maintaining the radiation dose at the patient optic nerve below a predetermined dose level. - View Dependent Claims (17, 18, 19, 20)
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Specification