Breast ultrasound examination including scanning through chestwardly compressing membrane and processing and displaying acquired ultrasound image information

• US 8,496,586 B2
• Filed: 04/14/2010
• Issued: 07/30/2013
• Est. Priority Date: 11/28/2003
• Status: Active Grant

• Current Assignee: U-System Inc. (General Electric Company)
• Original Assignee: U-System Inc. (General Electric Company)
• Inventors: Zhang, Wei, Chen, Jiayu, Neff, Thomas P., Reed, Michael E., Rader, Jeanine M., Summers, Douglas G., Wang, Shih-Ping, Anderson, Tor C., Yu, Zengpin, Cupples, Tommy Earl
• Primary Examiner(s): Jung, Unsu
• Assistant Examiner(s): Selkin, Saurel J
• Application Number:
  US12/760,382
• Publication Number:
  US 20100280375A1
• Time in Patent Office: 1,203 Days
• Field of Search: 600/437, 600/443
• US Class Current: 600/437
• CPC Class Codes: A61B 6/463 characterised by displaying multiple images or images and diagnostic data on one display
• CPC Class Codes: A61B 6/502 for diagnosis of breast, i.e. mammography
• CPC Class Codes: A61B 6/5247 combining images from an ionising-radiation diagnostic technique and a non-ionising radiation diagnostic technique, e.g. X-ray and ultrasound
• CPC Class Codes: A61B 6/563 involving image data transmission via a network
• CPC Class Codes: A61B 8/0825 for diagnosis of the breast, e.g. mammography
• CPC Class Codes: A61B 8/13 Tomography A61B8/10, A61B8/12 take precedence; tomography for radiation diagnosis A61B6/02
• CPC Class Codes: A61B 8/406 using means for diagnosing suspended breasts
• CPC Class Codes: A61B 8/4281 characterised by sound-transmitting media or devices for coupling the transducer to the tissue
• CPC Class Codes: A61B 8/4405 Device being mounted on a trolley
• CPC Class Codes: A61B 8/462 characterised by constructional features of the display
• CPC Class Codes: A61B 8/463 characterised by displaying multiple images or images and diagnostic data on one display composite display in devices for short-range imaging with acoustic waves G01S7/52074
• CPC Class Codes: A61B 8/465 adapted to display user selection data, e.g. icons or menus
• CPC Class Codes: A61B 8/466 adapted to display 3D data 3D imaging and stereoscopic displays in devices for short-range imaging with acoustic waves G01S15/8993 and G01S7/52068, respectively; 3D image rendering G06T15/00; manipulating 3D models for computer graphics G06T19/00
• CPC Class Codes: A61B 8/467 characterised by special input means
• CPC Class Codes: A61B 8/469 for selection of a region of interest
• CPC Class Codes: A61B 8/483 involving the acquisition of a 3D volume of data
• CPC Class Codes: A61B 8/5238 for combining image data of patient, e.g. merging several images from different acquisition modes into one image for image registration algorithms G06T7/30
• CPC Class Codes: A61B 8/565 involving data transmission via a network

Abstract

Navigation among breast ultrasound volumes derived from different volumetric ultrasonic scans of a same breast is described. On a display of a breast ultrasound workstation, a first image derived from a first ultrasonic volume is displayed. A user election of a source region of interest (ROI) in the first image is received. A destination ROI within a second ultrasonic volume is identified that at least roughly corresponds to a same locality of tissue in the breast as the source ROI. A second image derived from the second ultrasonic volume and including the destination ROI is displayed, the destination ROI being highlighted.

Claims

1. A system for ultrasound examination of an upwardly facing breast of a supine patient, comprising:

a support and a compression/scanning module supported thereby and configured to move under hand control of an operator from a non-scanning position above the supine patient and out of contact with the supine patient'"'"'s breast to a scanning position upon the supine patient and in contact with the breast, the compression/scanning module comprising;

(i) a housing member supported by the support and shaped for said hand control of the compression/scanning module by the operator, said housing member having a lower opening;

(ii) an ultrasound transducer movably disposed within said housing member;

(iii) an ultrasonically transparent compressive membrane secured across said lower opening in said housing member, said membrane and said housing member forming a general enclosure within which said ultrasound transducer is movably maintained, said compressive membrane being positioned to contact the breast and compress the breast in a chestward direction when the compression/scanning module is in said scanning position; and

(iv) an actuator disposed within said housing member and coupled to the ultrasound transducer and configured, when the compression/scanning module is in said scanning position, to translate the ultrasound transducer across the compressive membrane, said ultrasound transducer thereby scanning the chestwardly compressed breast through said membrane to acquire image data representative of a three-dimensional data volume of a sonographic property of the chestwardly compressed breast;

wherein said housing member and said membrane are each optically transparent at locations thereon sufficient for the operator to visually observe a skin surface of the chestwardly compressed breast, including a nipple location thereon, through the housing member and through the membrane when the compression/scanning module is in said scanning position;

a processor configured to receive and process the image data representative of the three-dimensional data volume to generate therefrom (a) a plurality of two-dimensional coronal ultrasound images, each coronal ultrasound image representing said sonographic property of the chestwardly compressed breast along one of a slice and slab subvolume thereof substantially parallel to a coronal plane of the patient, and (b) a plurality of two-dimensional axial ultrasound images, each axial ultrasound image representing said sonographic property of the chestwardly compressed breast along one of a slice and slab subvolume thereof substantially parallel to an axial plane of the patient; and

a computerized display configured to receive and selectively display said coronal ultrasound images and said axial ultrasound images;

wherein said processor is further configured to receive information indicative of said nipple location as visually observed and indicated by the operator with said compression/scanning module in said scanning position and to process said information indicative of the nipple location in conjunction with said image data representative of the three-dimensional data volume to determine a nipple location corresponding to each of said coronal ultrasound images; and

wherein said computerized display is further configured to display a nipple marker with each said coronal ultrasound image at said determined nipple location thereon.

2. The system of claim 1, wherein each of said plurality of coronal ultrasound images is a coronal thick-slice image representing said sonographic property of the chestwardly compressed breast along a slab subvolume thereof substantially parallel to the coronal plane of the patient and having a thickness in the range of about 2 mm-20 mm.

3. The system of claim 1, wherein each of said plurality of coronal ultrasound images is a coronal thin-slice image representing said sonographic property of the chestwardly compressed breast along a thin slice thereof substantially parallel to the coronal plane of the patient.

4. The system of claim 1, wherein said processor is further configured to receive at least one viewer input indicative of whether each said displayed coronal ultrasound image is desired to be (i) a coronal thick-slice image representing said sonographic property of the chestwardly compressed breast along a slab subvolume thereof substantially parallel to the coronal plane of the patient and having a thickness in the range of about 2 mm-20 mm, or (ii) a coronal thin-slice image representing said sonographic property of the chestwardly compressed breast along a thin slice thereof substantially parallel to the coronal plane of the patient and thinner than said thick-slice subvolume, and wherein said processor is further configured to generate each said coronal ultrasound image from said image data according to said at least one viewer input.

5. The system of claim 1, the computerized display being further configured to display concurrently with said coronal ultrasound images:

a body marker icon representative of a frontal view of the breast; and

a graphical outline upon said body marker icon indicative of a frontal area of the breast scanned by the ultrasound transducer in said automated translation across the compressive membrane.

6. The system of claim 5, further comprising a user interface including a pointing device for manipulation by a user, wherein said computerized display is further configured to display:

a cursor positioned upon one of said coronal ultrasound images according to user manipulation of the pointing device; and

a frontal breast icon including a central location thereof, said frontal breast icon including a cursor position indicator variably positioned thereon relative to said central location in a manner that reflects a relative position between said cursor and said nipple marker on said coronal thick-slice image, the cursor position indicator moving relative to said center location on said frontal breast icon as the cursor moves relative to said nipple marker on said coronal ultrasound image responsive to the user manipulation of the pointing device.

7. The system of claim 1, wherein said computerized display is further configured to display a rotatable, three-dimensionally-appearing version of the three-dimensional data volume.

8. The system of claim 1, said housing member comprising a rigid upper surface opposite said lower opening, wherein said rigid upper surface consists of an optically transparent material to thereby allow the operator to visually observe the skin surface of the chestwardly compressed breast through both the rigid upper surface and the membrane when the compression/scanning module is in said scanning position.

9. A method for ultrasound examination of an upwardly facing breast of a supine patient, comprising:

providing a compression/scanning module comprising a housing member, an ultrasound transducer movably disposed within said housing member, an ultrasonically transparent compressive membrane secured across a lower opening defined in said housing member, said membrane and said housing member forming a general enclosure within which said ultrasound transducer is movably maintained, and an automated translation assembly disposed within said housing member and coupled to the ultrasound transducer;

selectively manipulating, by an operator, the compression/scanning module from a non-scanning position above the supine patient and out of contact with the breast to a scanning position in which the compressive membrane of the compression/scanning module compresses the breast in a chestward direction, wherein after the compression/scanning assembly is in said scanning position the automated translation assembly translates the ultrasound transducer across the compressive membrane to thereby scan the chestwardly compressed breast therethrough to acquire image data representative of a three-dimensional data volume of a sonographic property of the chestwardly compressed breast;

wherein said housing member and said membrane are each optically transparent at locations thereon sufficient for the operator to visually observe a skin surface of the chestwardly compressed breast, including a nipple location thereon, through the housing member and through the membrane when the compression/scanning module is in said scanning position;

computer processing the image data representative of the three-dimensional data volume to generate therefrom (a) a plurality of two-dimensional coronal ultrasound images, each coronal ultrasound image representing said sonographic property of the chestwardly compressed breast along one of a slice and slab subvolume thereof substantially parallel to a coronal plane of the patient, and (b) a plurality of two-dimensional axial ultrasound images, each axial ultrasound image representing said sonographic property of the chestwardly compressed breast along one of a slice and slab subvolume thereof substantially parallel to an axial plane of the patient;

wherein said computer processing further comprises processing information indicative of said nipple location as visually observed and indicated by the operator in conjunction with said image data to determine a nipple location for each of said coronal ultrasound images; and

displaying said coronal ultrasound images and said axial ultrasound images on a computerized display, said coronal ultrasound images each including a nipple marker thereon at said determined nipple location.

10. The method of claim 9, wherein each of said plurality of coronal ultrasound images is a coronal thick-slice image representing said sonographic property of the chestwardly compressed breast along a slab subvolume thereof substantially parallel to the coronal plane of the patient and having a thickness in the range of about 2 mm-20 mm.

11. The method of claim 9, wherein each of said plurality of coronal ultrasound images is a coronal thin-slice image representing said sonographic property of the chestwardly compressed breast along a thin slice thereof substantially parallel to the coronal plane of the patient.

12. The method of claim 9, further comprising receiving, at a user interface associated with said computerized display, at least one input from a viewer of the computerized display indicative of whether each said displayed coronal ultrasound image is desired to be (i) a coronal thick-slice image representing said sonographic property of the chestwardly compressed breast along a slab subvolume thereof substantially parallel to the coronal plane of the patient and having a thickness in the range of about 2 mm-20 mm, or (ii) a coronal thin-slice image representing said sonographic property of the chestwardly compressed breast along a thin slice thereof substantially parallel to the coronal plane of the patient and thinner than said thick-slice subvolume, wherein said computer processing comprises generate each said coronal ultrasound image according to said at least one viewer input.

13. The method of claim 9, wherein said displaying said coronal ultrasound images further comprises displaying:

a body marker icon representative of a frontal view of the breast; and

a graphical outline upon said body marker icon representing a frontal area of the breast scanned by the ultrasound transducer in said automated translation across the compressive membrane.

14. The method of claim 13, further comprising receiving, at a user interface associated with said computerized display, inputs corresponding to manipulations of a pointing device by a viewer, wherein said displaying said coronal ultrasound images further comprises displaying:

a cursor positioned upon one of said coronal ultrasound images according to the user manipulation of the pointing device; and

a frontal breast icon including a central location, said frontal breast icon including a cursor position indicator variably positioned thereon relative to said central location in a manner that reflects a relative position between said cursor and said nipple marker on said coronal thick-slice image, the cursor position indicator moving relative to said center location on said frontal breast icon as the cursor moves relative to said nipple marker on said coronal ultrasound image responsive to the viewer manipulation of the pointing device.

15. The method of claim 9, wherein said computerized display further displays a rotatable, three-dimensionally-appearing version of the three-dimensional data volume.

16. The method of claim 9, wherein said housing member comprises a rigid upper surface opposite said lower opening, wherein said rigid upper surface consists of an optically transparent material to thereby allow the operator to visually observe the skin surface of the chestwardly compressed breast through both the rigid upper surface and the membrane when the compression/scanning module is in said scanning position.