Fluid delivery systems for delivering fluids to multi-lumen catheters

• US 8,496,620 B2
• Filed: 11/04/2005
• Issued: 07/30/2013
• Est. Priority Date: 08/24/2000
• Status: Active Grant

• Current Assignee: Cardinal Health Switzerland 515 GmbH (Cardinal Health, Inc.)
• Original Assignee: Cordis Corporation (Cardinal Health, Inc.)
• Inventors: Constantz, Brent R., Johansson, Peter K.
• Primary Examiner(s): Sirmons, Kevin C
• Assistant Examiner(s): GILBERT, ANDREW M
• Application Number:
  US11/267,944
• Publication Number:
  US 20060178621A1
• Time in Patent Office: 2,825 Days
• Field of Search: 604/101.01, 604/101.03, 604/101.05, 604/102.01, 604 43- 45, 604/258, 604/276, 604/508, 604/510, 604/523, 604/284
• US Class Current: 604/151
• CPC Class Codes: A61M 2025/1052 for temporarily occluding a vessel for isolating a sector
• CPC Class Codes: A61M 25/0026 Multi-lumen catheters with stationary elements catheter assemblies comprising a catheter in combination with a guide tube, sheath or sleeve A61M2025/0681; catheters comprising telescoping coaxial elements A61M2025/0175
• CPC Class Codes: A61M 25/104 used for angioplasty
• CPC Class Codes: A61M 5/142 Pressure infusion, e.g. using pumps
• CPC Class Codes: A61M 5/16827 controlling delivery of multiple fluids, e.g. sequencing, mixing or via separate flow-paths infusion of multiple fluids without using a controller A61M5/1407
• CPC Class Codes: A61M 5/19 having more than one chamber , e.g. including a manifold coupling two parallelly aligned syringes through separate channels to a common discharge assembly surgical glue applicators A61B17/00491

Abstract

Fluid delivery systems capable of introducing first and second fluids into first and second lumens of a multi-lumen catheter are provided. The first and second fluids are generally a dissolution fluid and a dissolution fluid attenuating fluid. Also provided are fluid delivery devices and kits that include the subject systems. The subject fluid delivery systems find use in a variety of different applications, and are particularly suited for use in the chemical ablation of internal vascular lesions.

Claims

1. A system for simultaneously flushing an internal site with two different fluids, said system comprising;

(a) a multi-lumen catheter system comprising first, second and third lumens;

(b) an automatic metered fluid delivery system comprising a first external reservoir containing a first fluid, which is a dissolution fluid, and a second external reservoir containing a second fluid, which is a dissolution fluid attenuating fluid, wherein said metered fluid delivery system is configured to automatically control the delivery of said first and second fluids into said first and second lumens of said multi-lumen catheter system at substantially the same flow rate to maintain to pressure substantially constant at an internal site;

(c) a negative pressure means sufficient to aspirate fluid from said third lumen of said multi-lumen catheter system;

(d) a balloon inflation means, including a balloon inflation lumen, wherein said dissolution fluid consisting of at least one of a surfactant/detergent solution or an acidic solution and, said dissolution fluid attenuating fluid comprising an extracorporeal fluid consisting of at least one of a dilution solution or a pH elevating solution, wherein said automatic metered fluid delivery system is configured to deliver said dissolution fluid and said dissolution fluid attenuating fluid to a target lesion in a body, each of said dissolution fluid and said dissolution fluid attenuating fluid being individually controlled by pressure regulation of the external reservoirs using a force of between about 500 pounds to about 600 pounds.

2. The system according to claim 1, wherein said first and second external fluid reservoirs are present in a cartridge.