Peristaltic micropump with exchangeable pump head

• US 8,496,621 B2
• Filed: 03/31/2009
• Issued: 07/30/2013
• Est. Priority Date: 10/07/2006
• Status: Active Grant

• Current Assignee: Sanofi-Aventis Deutschland GmbH (Sanofi )
• Original Assignee: Sanofi-Aventis Deutschland GmbH (Sanofi )
• Inventors: Basso, Nils, Pommereau, Christian, Richter, Ren, Clarke, Alastair
• Primary Examiner(s): Lucchesi, Nicholas
• Assistant Examiner(s): MATNEY, BROOKE MARIE
• Application Number:
  US12/415,232
• Publication Number:
  US 20090292247A1
• Time in Patent Office: 1,582 Days
• Field of Search: 604/151, 604/891.1, 604/519, 604/520, 604/31, 604/67, 604/71, 604/72, 604/122, 417/313, 417/474, 417/14, 417/53, 417/477.1, 417/477.2, 453/3
• US Class Current: 604/151
• CPC Class Codes: A61M 2005/14268 with a reusable and a disposable component
• CPC Class Codes: A61M 2205/8293 Solar
• CPC Class Codes: A61M 5/14232 Roller pumps
• CPC Class Codes: A61M 5/14244 adapted to be carried by the patient, e.g. portable on the body
• CPC Class Codes: F04B 2201/0207 Number of pumping strokes in unit time
• CPC Class Codes: F04B 23/028 the pump being mounted on top of the reservoir
• CPC Class Codes: F04B 43/1253 by using two or more rollers as squeezing elements, the rollers moving on an arc of a circle during squeezing

Abstract

The present invention relates to a device for injecting a pharmaceutical into the human or animal body by means of a simply and quickly exchangeable motorized pump head.

Claims

1. An injection device for injecting a pharmaceutical, the injection device comprising:

a) an injection device body;

b) a motor within the device body;

c) a cartridge compartment within the injection device body, the cartridge compartment configured to receive a cartridge containing the pharmaceutical, the cartridge comprising a cylinder having an interior treated surface to reduce sliding forces of a movable stopper sealing one end of the cylinder and a cannula puncturable sealing disk sealing a second end of the cylinder, where the moveable stopper is configured to be slidably displaced axially towards the sealing disk within the cylinder to bring about a change in volume of the cylinder during injection;

d) an exchangeable pump head of a peristaltic pump which is driven by the motor and by means of which the pharmaceutical is conveyed out of the cartridge; and

e) control electronics comprising an adjusting mechanism, the adjusting mechanism allows presetting an amount of the pharmaceutical to be injected, the control electronics contained within the injection device body;

wherein the exchangeable pump head is configured to be detachable from and reconnectable to both the motor and the cartridge and comprises

detachable and functionally reconnectable interfaces to directly connect the exchangeable pump head to the motor and

detachable and functionally reconnectable interfaces to directly connect the exchangeable pump head to the cartridge.

2. The device as claimed in claim 1, wherein the pump head can be exchanged without employing a tool for another pump head.

3. The device as claimed in claim 1, wherein the pump head comprises a flow sensor and components of the flow sensor.

4. The device as claimed in claim 1, wherein the pump head carries a needle.

5. The device as claimed in claim 1, wherein the motor consists of a micromotor.

6. The device as claimed in claim 1, wherein the device is configured to exchangeably contain the cartridge.

7. The device as claimed in claim 1, wherein the cartridge comprises insulin.

8. A medical device for injecting a substance into a human or animal body comprising a device according to claim 1.

9. The production of a device as claimed in claim 1, where

a) a motor is provided;

b) a cartridge is provided;

c) a pump head is provided; and

d) the individual constituents as described in a) to c) are assembled to give a functional unit.

10. A medical apparatus for injecting a pharmaceutical, comprising inter alia

a) a display;

and

b) a technical unit in the form of a release mechanism for starting up and carrying out the injection;

which additionally comprises at least one device as claimed in claim 1.

11. The medical apparatus as claimed in claim 10, wherein the display consists of an LCD display.

12. The medical apparatus as claimed in claim 10, which comprises

at least one means for storing and processing data and signals, and

at least one interface for transmitting data and signals to and from an external technical unit which is configured to store and process data and signals.

13. The medical apparatus as claimed in claim 10, which comprises at least one means for storing or processing data or signals, and at least one interface for transmitting data or signals to or from an external technical unit which is configured to store or process data or signals.

14. The medical apparatus as claimed in claim 13, wherein the external technical unit consists of a PC on which a program for storing or processing data or signals is installed.

15. The medical apparatus as claimed in claim 10, wherein the pharmaceutical intended for injection consists of insulin.

16. The medical apparatus as claimed in claim 15, in which the insulin is a long-acting or short-acting insulin.

17. The medical apparatus as claimed in claim 10, wherein the pharmaceutical intended for injection consists of GLP-1.

18. The medical apparatus as claimed in claim 10, wherein the pharmaceutical intended for injection consists of a heparin.

19. The production of a medical apparatus for injecting a pharmaceutical as claimed in claim 10, where at least

a) a display is provided;

b) a release mechanism is provided;

c) a device for moving liquids which comprise a pharmaceutical is provided, the device comprising a least a motor, a cartridge, a pump head which is driven by the motor and by means of which the liquid is conveyed out of the reservoir, control electronics, wherein the pump head is equipped with detachable and functionally reconnectable interfaces to the motor; and

d) at least the individual constituents as described in a) to e) are assembled to give a functional unit.

20. The production of a medical apparatus for injecting pharmaceutical as claimed in claim 19, where furthermore electronic constituents are provided and the electronic constituents being assembled with the individual constituents to give the functional unit.

21. A medical apparatus for the administration of a substance, whose pharmaceutical activity is diminished or lost in the gastrointestinal tract, for the prophylaxis or therapy of a disease or dysfunction of the body, comprising a medical apparatus according to claim 10.

22. The apparatus according to claim 21, wherein the disease is diabetes.

23. The apparatus according to claim 21, wherein the substance is insulin.

24. The apparatus according to claim 21, wherein the substance is GLP-1.

25. The apparatus according to claim 21, wherein the substance is a peptide hormone.

26. The apparatus according to claim 21, wherein the substance is a growth hormone.

27. The apparatus according to claim 21, wherein the substance is a heparin.

28. The apparatus according to claim 21, wherein the substance is Lovenox.

29. The apparatus according to claim 21, wherein the substance is a vaccine.

30. The device as claimed in claim 1, the device being a technical device.

31. The device as claimed in claim 1, wherein the pump head is furthermore equipped with detachable and functionally reconnectable interfaces to the control electronics.

32. The device as claimed in claim 1, wherein the cartridge is provided separately from the pump head, in particular in a unit comprising the motor and the control electronics.

33. The device as claimed in claim 1, wherein the pump head is removably coupled to the injection device body.

34. A device for injecting a pharmaceutical, the device comprising at least:

a housing including a motor, the housing configured to receive a cartridge comprising a cylinder having an interior treated surface to reduce sliding forces of a moveable stopper and a sealing disk, where the sealing disk is puncturable by a cannula and where the moveable stopper is configured to be displaced to bring about a change in volume of the cartridge during injection;

control electronics;

an exchangeable pump head for a peristaltic pump configured to be detachable from and reconnectable to both the housing and the control electronics,

the pump head driven by the motor and by means of which the pharmaceutical is conveyed out of the cartridge, the pump head being equipped with detachable and functionally reconnectable interfaces to the motor.