Implantable putty material
First Claim
1. An implantable moldable putty material for delivery of an active ingredient to a patient comprising collagen and a first acidic solution having a pH between about 3 and about 6, wherein the collagen has been combined with a sufficient amount of the first acidic solution and formed the moldable putty material, wherein the collagen was previously processed by combining the collagen with a second acidic solution and lyophilizing the combined collagen and second acidic solution;
- wherein the first acidic solution includes an acid different from an acid included in the second acidic solution, wherein said putty material has at least one physical property selected from the group consisting of a peak resistance force of at least about 10 g and an extensibility of from about 2 mm to about 25 mm.
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Abstract
The present invention provides compositions for an implantable putty material for delivery of active compounds to a patient. More specifically, the present invention provides a material having a pH of between about 3 and 6 and possessing putty-like physical properties, wherein the composition of the material includes collagen and water. The present invention also provides a method for using the implantable putty material.
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Citations
18 Claims
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1. An implantable moldable putty material for delivery of an active ingredient to a patient comprising collagen and a first acidic solution having a pH between about 3 and about 6, wherein the collagen has been combined with a sufficient amount of the first acidic solution and formed the moldable putty material, wherein the collagen was previously processed by combining the collagen with a second acidic solution and lyophilizing the combined collagen and second acidic solution;
- wherein the first acidic solution includes an acid different from an acid included in the second acidic solution, wherein said putty material has at least one physical property selected from the group consisting of a peak resistance force of at least about 10 g and an extensibility of from about 2 mm to about 25 mm.
- View Dependent Claims (2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 16, 17, 18)
Specification