Method of moving a delivery member of a dispensing device for administration of oral transmucosal dosage forms
First Claim
1. A method, comprising:
- inserting a distal end portion of a housing of a device into a mouth, the device configured to deliver a bioadhesive, small-volume, solid drug tablet containing a dosage of sufentanil;
moving an end portion of a delivery member to a first stopped position within a delivery passage defined by the housing, a distal end portion of the housing defining an exit opening and a tablet cartridge channel, a surface of the delivery member positioned to prevent movement of the drug tablet from the tablet cartridge channel to the delivery passage when the end portion of the delivery member is in the first stopped position;
moving the end portion of the delivery member in a proximal direction to a second position within the delivery passage such that the tablet cartridge channel is in communication with the delivery passage;
conveying the drug tablet into the delivery passage via the tablet cartridge channel; and
moving the end portion of the delivery member in a distal direction to a third position within the delivery passage to convey the drug tablet through the exit opening.
2 Assignments
0 Petitions
Accused Products
Abstract
A method of administering small, bioadhesive drug tablets includes moving an end portion of a delivery member. A surface of the delivery member can be positioned to prevent movement of the drug tablet from a tablet cartridge channel to a delivery passage of a delivery device when the end portion of the delivery member is in a first stopped position. The end portion of the delivery member can be moved to a second position within the delivery passage such that the tablet cartridge channel is in communication with the delivery passage. The drug tablet can be conveyed into the delivery passage via the tablet cartridge channel. The end portion of the delivery member can be moved to a third position within the delivery passage to convey the drug tablet through an exit opening of the delivery device.
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Citations
28 Claims
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1. A method, comprising:
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inserting a distal end portion of a housing of a device into a mouth, the device configured to deliver a bioadhesive, small-volume, solid drug tablet containing a dosage of sufentanil; moving an end portion of a delivery member to a first stopped position within a delivery passage defined by the housing, a distal end portion of the housing defining an exit opening and a tablet cartridge channel, a surface of the delivery member positioned to prevent movement of the drug tablet from the tablet cartridge channel to the delivery passage when the end portion of the delivery member is in the first stopped position; moving the end portion of the delivery member in a proximal direction to a second position within the delivery passage such that the tablet cartridge channel is in communication with the delivery passage; conveying the drug tablet into the delivery passage via the tablet cartridge channel; and moving the end portion of the delivery member in a distal direction to a third position within the delivery passage to convey the drug tablet through the exit opening. - View Dependent Claims (2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12)
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13. A method, comprising:
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inserting a distal end portion of a housing of a device into a mouth, the device configured to deliver a bioadhesive, small-volume, solid drug tablet containing a dosage of sufentanil from a tablet cartridge; moving a first end portion of a delivery member to a first stopped position within a delivery passage defined by the housing of the device, the housing further defining an exit opening; moving the first end portion of the delivery member in a proximal direction to a second position within the delivery passage to receive the drug tablet from the tablet cartridge; and rotating a second end portion of the delivery member to move the first end portion of the delivery member in a distal direction to a third position within the delivery passage to convey the drug tablet through the exit opening. - View Dependent Claims (14, 15, 16, 17, 18, 19, 20)
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21. A method, comprising:
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inserting a distal end portion of a housing of a device into a mouth, the device configured to deliver a bioadhesive, small-volume, solid drug dosage tablet containing a dosage of sufentanil from a tablet cartridge; moving, at a first time, an end portion of a delivery member in a distal direction to a stopped position within a delivery passage defined by the housing to convey a shipping tablet through an exit opening defined by the housing; producing a signal uniquely associated with the shipping tablet during the moving; moving, at a second time, the end portion of the delivery member in a proximal direction within the delivery passage to receive the drug dosage tablet from the tablet cartridge; and moving, at a third time, the end portion of the delivery member in the distal direction within the delivery passage to convey the drug dosage tablet through the exit opening. - View Dependent Claims (22, 23, 24, 25, 26, 27, 28)
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Specification