Integrated cardiac rhythm management system with heart valve

• US 8,504,151 B2
• Filed: 08/02/2012
• Issued: 08/06/2013
• Est. Priority Date: 08/24/2006
• Status: Active Grant

• Current Assignee: Cardiac Pacemakers Incorporated (Boston Scientific Corporation)
• Original Assignee: Cardiac Pacemakers Incorporated (Boston Scientific Corporation)
• Inventors: Shuros, Allan C., Kane, Michael J.
• Primary Examiner(s): GETZOW, SCOTT M
• Application Number:
  US13/564,978
• Publication Number:
  US 20120296382A1
• Time in Patent Office: 369 Days
• Field of Search: 623 21- 242, 607 4- 26
• US Class Current: 607/18
• CPC Class Codes: A61F 2/2403 with pivoting rigid closure members check valves with hinged closure members in general F16K15/03
• CPC Class Codes: A61N 1/3621 for treating or preventing abnormally high heart rate
• CPC Class Codes: A61N 1/36514 controlled by a physiological quantity other than heart potential, e.g. blood pressure controlled by two or more physical parameters A61N1/36585
• CPC Class Codes: A61N 1/39622 Pacing therapy

Abstract

Systems and methods using a heart valve and an implantable medical device, such as for event detection and optimization of cardiac output. The cardiac management system includes a heart valve, having a physiological sensor. The physiological sensor is adapted to measure at least one of an intrinsic electrical cardiac parameter, a hemodynamic parameter or the like. The system further includes an implantable electronics unit, such as a cardiac rhythm management unit, coupled to the physiological sensor of the heart valve to receive physiological information. The electronics unit is adapted to use the received physiological information to control delivery of an electrical output to the subject.

Claims

1. A system comprising:

a replacement heart valve configured to be implanted in a heart;

a physiological sensor coupled to the replacement heart valve, the physiological sensor configured to sense an intrinsic electrical cardiac signal of the heart; and

a medical device configured to provide pacing therapy or defibrillation therapy to the heart, the medical device in communication with the physiological sensor and configured to adjust the pacing therapy or the defibrillation therapy to the heart based on the sensed intrinsic electrical cardiac signal.

2. The system of claim 1, wherein the replacement heart valve includes at least one electrode serving as the physiological sensor.

3. The system of claim 1, wherein the medical device is an implantable medical device.

4. The system of claim 1, wherein the physiological sensor is configured to sense a hemodynamic parameter.

5. The system of claim 4, wherein the medical device is configured to use one or more of the hemodynamic parameter and the electrical cardiac signal measured at the replacement heart valve to detect a cardiac event, and the medical device is configured to use one or more of the hemodynamic parameter and the electrical cardiac signal measured at the replacement heart valve to classify the cardiac event.

6. The system of claim 4, wherein the medical device is configured to use the hemodynamic parameter and the electrical cardiac signal to detect a tachyarrhythmia and to declare the tachyarrhythmia as a first tachyarrhythmia type when a hemodynamic parameter value is below a specified threshold or to declare the tachyarrhythmia as a second tachyarrhythmia type when the hemodynamic parameter value is above a specified threshold.

7. The system of claim 1, wherein the medical device controls the delivery of electrical output including one or more of defibrillation therapy, pacing therapy, and resynchronization therapy.

8. A medical device system comprising:

a replacement heart valve configured to be implanted in an aorta of a patient, the replacement heart valve including a physiological sensor configured to sense;

an intrinsic electrical cardiac signal, and

a hemodynamic parameter indicative of a blood hemodynamic characteristic sensed at the replacement heart valve.

9. The medical device system of claim 8 comprising an implantable electronics unit in communication with the physiological sensor of the replacement heart valve, the implantable electronics unit configured to receive physiological information about the sensed intrinsic electrical cardiac signal and the sensed hemodynamic parameter to control delivery of an electrical therapy to the patient.

10. The medical device system of claim 9, wherein the implantable electronics unit is configured to use one or more of the hemodynamic parameter and the electrical cardiac signal measured at the replacement heart valve to detect a cardiac event, and the implantable electronics unit is configured to use one or more of the hemodynamic parameter and the electrical cardiac signal measured at the replacement heart valve to classify the cardiac event.

11. The medical device system of claim 8, wherein the replacement heart valve includes one or more of at least one defibrillation electrode, or at least one pacing electrode.

12. The medical device system of claim 8, wherein the hemodynamic parameter sensor includes one or more of a blood flow sensor, a pressure sensor, or a valve deflection sensor.

13. An apparatus comprising:

a replacement heart valve configured to be implanted in an aorta of a patient, the replacement heart valve including;

at least one valve leaflet;

a support member configured to support the at least one valve leaflet; and

a physiological sensor coupled to the support member, the physiological sensor including one or more electrodes, the physiological sensor configured to sense an intrinsic electrical cardiac signal of a heart of the patient.

14. The apparatus of claim 13 further including a transmitter configured to transmit a signal corresponding to the sensed intrinsic electrical cardiac signal to an implantable medical device to adjust a therapy, or the transmitter is configured to transmit an alert to an external system.

15. The apparatus of claim 13, wherein the replacement heart valve includes one or more of at least one defibrillation electrode, or at least one pacing electrode.

16. The apparatus of claim 13 comprising an implantable electronics unit coupled to the physiological sensor of the replacement heart valve, the implantable electronics unit configured to receive physiological information about the intrinsic electrical cardiac signal, the implantable electronics unit adapted to use the received physiological information to control delivery of an electrical output to the subject.

17. The apparatus of claim 13, wherein the physiological sensor includes a second physiological parameter sensor configured to sense another physiological parameter different from the intrinsic electrical cardiac signal.

18. The apparatus of claim 17, wherein the second physiological parameter sensor includes a hemodynamic parameter sensor configured to sense at the replacement heart valve a hemodynamic parameter indicative of a blood hemodynamic characteristic.

19. The apparatus of claim 18, wherein the hemodynamic parameter sensor includes one or more of a blood flow sensor, a pressure sensor, or a valve deflection sensor.

20. The apparatus of claim 17, wherein the second physiological parameter sensor includes one or more of a temperature sensor or a chemical sensor.