Cranially mounted stimulation systems and methods

• US 8,504,163 B1
• Filed: 06/30/2006
• Issued: 08/06/2013
• Est. Priority Date: 06/30/2006
• Status: Active Grant

• Current Assignee: Boston Scientific Neuromodulation Corporation (Boston Scientific Corporation)
• Original Assignee: Boston Scientific Neuromodulation Corporation (Boston Scientific Corporation)
• Inventors: Meadows, Paul M.
• Primary Examiner(s): Holmes, Rex R
• Application Number:
  US11/479,707
• Time in Patent Office: 2,594 Days
• Field of Search: 607/1, 607/2, 607 45- 46, 607/115, 607/116
• US Class Current: 607/57
• CPC Class Codes: A61M 2039/025 through bones or teeth, e.g. through the skull
• CPC Class Codes: A61M 2039/0261 Means for anchoring port to the body, or ports having a special shape or being made of a specific material to allow easy implantation/integration in the body
• CPC Class Codes: A61N 1/0534 Electrodes for deep brain stimulation
• CPC Class Codes: A61N 1/0539 Anchoring of brain electrode systems, e.g. within burr hole
• CPC Class Codes: A61N 1/36064 Epilepsy
• CPC Class Codes: A61N 1/36067 Movement disorders, e.g. tremor or Parkinson disease stimulating motor muscle A61N1/36003
• CPC Class Codes: A61N 1/36082 Cognitive or psychiatric applications, e.g. dementia or Alzheimer's disease

Abstract

An exemplary system includes a stimulator with a hollow lumen extending therethrough and configured to be at least partially disposed within a burr hole in a cranium of a patient, a stimulating member configured to apply a stimulus to a stimulation site within the patient, and coupling member configured to extend at least partially through the lumen and couple the stimulating member to the stimulator. Exemplary methods of applying at least one stimulus to a stimulation site within a patient include implanting a lead with a number of electrodes disposed thereon within a cavity formed by a cranium, implanting a stimulator such that the stimulator is at least partially disposed within a burr hole in the cranium, removably coupling the lead to the stimulator, and applying the at least one stimulus to a stimulation site within the cavity formed by the cranium via one or more of the electrodes.

Claims

1. A system comprising:

a stimulator including a housing having opposing top and bottom surfaces and configured to be at least partially disposed within a burr hole in a cranium of a patient, electronic circuitry contained within said housing and configured to generate an electrical stimulus, a first number of electrical contacts and a first registration element disposed on said bottom surface of said housing, and a hollow lumen extending through said housing and terminating in said opposing surfaces, wherein said lumen has a longitudinal axis, and said opposing surfaces of said housing are respectively located at opposite ends of said longitudinal axis;

a stimulating member having a lead and a number of electrodes disposed on said lead for applying said electrical stimulus to a stimulation site within said patient;

a connector member coupled to a proximal portion of said stimulating member, said connector member having opposing top and bottom surfaces, a hollow lumen, a second number of electrical contacts and a second registration element disposed on said top surface of said connector member, wherein said first and second registration elements correspond to each other to align said first and second numbers of electrical contacts with each other; and

a coupling member configured to extend through said lumens of said stimulator and said connector member and apply opposing forces to said housing and said connector member to secure said stimulating member to said housing, such that said electrical contacts of said stimulator are electrically coupled to said electrical contacts of said connector member.

2. The system of claim 1, wherein said stimulator further comprises a lip member coupled to said housing and configured to extend a distance along an outer surface of said cranium, wherein said lip member is configured to prevent said stimulator from falling into said cavity formed by said cranium.

3. The system of claim 1, wherein said coupling member comprises:

a shaft member configured to extend through said lumens of said stimulator and said connector member; and

a fastening device configured to secure said shaft member to said housing and said connector member.

4. The system of claim 3, wherein said fastening device comprises at least one or more of a nut, a clamp, and a rivet.

5. The system of claim 1, further comprising a securing device configured to secure said stimulator in said burr hole.

6. The system of claim 1, wherein said coupling member is further configured to hermetically couple said stimulating member to said housing.

7. A method of using the system of claim 1, comprising:

implanting said stimulating member and connector member within said patient;

implanting said stimulator within said burr hole; and

extending said coupling member through said lumens of said stimulator and said connecting member to secure said stimulating member to said housing.

8. The method of claim 7, further comprising securing said stimulator within said burr hole.

9. The method of claim 7, further comprising applying said at least one stimulus to a stimulation site within said patient via said stimulating member.

10. The system of claim 2, further comprising a communication port disposed on a top surface of said lip member for communicating with an external device.

11. The system of claim 1, wherein said first registration element comprises one of a depression and a protrusion corresponding to said depression a different one of said depression and said protrusion.

12. The system of claim 1, further comprising:

a third registration element disposed on a top surface of said coupling member; and

a fourth registration element disposed on said bottom surface of said connector member, wherein said third and fourth registration elements correspond to each other.

13. The system of claim 1, wherein said connecting member comprises a lumen extending therethrough, and said coupling member configured to extend through said lumen of said connector member to secure said connector member to said housing.

14. The system of claim 1, wherein said coupling member is configured to secure said stimulating member to said housing while said stimulating member is disposed within said patient.

15. The system of claim 13, wherein said coupling member is configured to press said top surface of said connecting member against said bottom surface of said housing to secure said connector member to said housing.

16. The system of claim 1, wherein said opposing surfaces of said housing are substantially parallel to each other and substantially perpendicular to said longitudinal axis of said lumen.

17. The method of claim 7, wherein said coupling member comprises a shaft member and a fastening device, the method further comprising:

extending said shaft member through said lumens of said stimulator and said connector member; and

fastening said fastening device to said shaft member to secure said stimulating member to said housing.

18. The method of claim 17, wherein said fastening device is fastened to said shaft member after said stimulating member and said connector member are implanted within said patient.