Micronized peptide coated stent
First Claim
Patent Images
1. A stent comprising:
- a stent body;
a coating on a surface of the stent body, the coating comprising a polymer, and;
an unencapsulated micronized peptide or protein dispersed in the polymer, wherein;
the peptide or protein comprises from 5 to 1000 L-arginine subunits, or analogs or derivatives thereof.
1 Assignment
0 Petitions
Accused Products
Abstract
A coating for an implantable device such as a stent is provided including micronized peptides. A method of making the same is also provided.
331 Citations
33 Claims
-
1. A stent comprising:
-
a stent body; a coating on a surface of the stent body, the coating comprising a polymer, and; an unencapsulated micronized peptide or protein dispersed in the polymer, wherein; the peptide or protein comprises from 5 to 1000 L-arginine subunits, or analogs or derivatives thereof. - View Dependent Claims (2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15)
-
-
16. A stent, comprising:
-
a stent substrate; a coating on a surface of the stent substrate, the coating comprising a polymer, and; an unencapsulated micronized peptide or protein having an average particle size of less than 2 microns dispersed in the polymer. - View Dependent Claims (17, 18, 19, 20, 21, 22, 23, 24)
-
-
25. An implantable medical device comprising:
-
a substrate; a coating on the substrate, the coating comprising a hydrophobic polymer, and; an unencapsulated micronized polycationic peptide or protein dispersed in the hydrophobic polymer, wherein the micronized polycationic peptide or protein has an average particle size of less than 5 microns. - View Dependent Claims (26, 27, 28, 29, 30, 31, 32, 33)
-
Specification