Multi-electrode implantable systems and assemblies thereof

• US 8,509,899 B2
• Filed: 01/18/2011
• Issued: 08/13/2013
• Est. Priority Date: 12/23/2010
• Status: Active Grant

• Current Assignee: Medtronic Incorporated (Medtronic Plc)
• Original Assignee: Medtronic Incorporated (Medtronic Plc)
• Inventors: Sommer, John Louis, D'Sa, Joseph Michael, Yamamoto, Joyce K., Tischendorf, Brad C., Reinke, James D., Thom, Andrew J., Miltich, Thomas P., Taylor, William John, Gardeski, Kenneth C., Tyler, Larry Earl, York, Jeffrey O., Munns, Gordon O.
• Primary Examiner(s): Holmes, Rex R
• Application Number:
  US13/008,524
• Publication Number:
  US 20120165902A1
• Time in Patent Office: 938 Days
• Field of Search: 607 36- 38
• US Class Current: 607/37
• CPC Class Codes: A61N 1/05 for implantation or insertion into the body, e.g. heart electrode A61N1/06 takes precedence
• CPC Class Codes: A61N 1/056 Transvascular endocardial electrode systems
• CPC Class Codes: A61N 1/362 Heart stimulators heart defibrillators A61N1/39
• CPC Class Codes: A61N 1/372 Arrangements in connection with the implantation of stimulators

Abstract

Hermetically sealed assemblies, for example, that include IC chips, are configured for incorporation within a connector terminal of an implantable medical electrical lead, preferably within a contact member of the terminal. An assembly may include two feedthrough subassemblies, welded to either end of the contact member, to form an hermetic capsule, in which an IC chip is enclosed, and a tubular member, which allows a lumen to extend therethrough, along a length of the terminal. A multi-electrode lead may include multiplexer circuitry, preferably a switch matrix element and a communications, control and power supply element that are electrically coupled to the contact member and to another contact member of the terminal. Each pair of switch matrix switches allows for any two of the electrodes to be selected, in order to deliver a stimulation vector, via stimulation pulses from a device/pulse generator, to which the connector terminal is connected.

Claims

1. A connector terminal for an implantable medical electrical lead, the connector terminal comprising:

a first electrical contact member and a second electrical contact member, the second contact member being electrically isolated from the first contact member and spaced apart, distally from the first contact member along a length of the connector terminal, and the second contact member having a proximal end and a distal end; and

a switching assembly comprising a multiplexer, a proximal feedthrough subassembly and a distal feedthrough subassembly, the multiplexer being mounted on an integrated circuit chip within the second connector contact member and electrically coupled to the second contact member, the proximal feedthrough subassembly including a conductive ferrule attached to the proximal end of the second contact member, a feedthrough pin and an insulator isolating the pin from the ferrule and being hermetically sealed to the pin and to the ferrule, the feedthrough pin electrically coupling the first contact member to the multiplexer, and the distal feedthrough subassembly including a conductive ferrule attached to the distal end of the second contact member, a plurality of feedthrough pins and an insulator isolating each of the pins from one another and from the ferrule of the distal subassembly, and being hermetically sealed to each of the pins and to the ferrule of the distal subassembly, each feedthrough pin of the distal subassembly being electrically coupled to the multiplexer and having a distal portion that extends distally from the distal end of the second contact member, the distal portions being positioned with respect to one another in order to allow for electrical coupling with a plurality of elongate conductors of the lead;

wherein the multiplexer includes a switch matrix element and a communications, control and power supply element, the switch matrix element including a plurality of pairs of switches, each pair of the plurality of pairs of switches corresponding to one of the feedthrough pins of the distal feedthrough assembly, a first of each pair of switches being adapted to connect and disconnect the corresponding feedthrough pin to/from the first contact member and the communications, control and power supply element, and a second of each pair of switches adapted to connect and disconnect the corresponding feedthrough pin to/from the second contact member and the communications, control and power supply element; and

each ferrule of the proximal and distal feedthrough assemblies is attached to the corresponding end of the proximal and distal ends of the second contact member by a weld that extends about an entire perimeter of the corresponding end.

2. The connector terminal of claim 1, further comprising a distal insulative support member;

and wherein;

the ferrule of the distal feedthrough subassembly includes a protrusion, which extends distally from the second contact member, and on which the distal support member is mounted;

the distal support member includes a plurality of relatively straight channels formed in an outer surface thereof and spaced apart from one another around a circumference of the distal support member; and

the distal portion of each distal feedthrough pin extends within a corresponding channel of the distal support member.

3. The connector terminal of claim 1, further comprising a proximal insulative support member and a conductive jumper that couples the first contact member to the proximal feedthrough pin;

and wherein;

the ferrule of the proximal feedthrough subassembly includes a protrusion, which extends proximally from the second contact member, and on which the proximal support member is mounted; and

the conductive jumper is wrapped about the proximal support member and coupled to the proximal feedthrough pin thereon.

4. The connector terminal of claim 3, wherein:

the proximal support member includes a relatively straight channel formed in an outer surface thereof; and

a proximal portion of the proximal feedthrough pin extends within the channel and beneath the jumper.

5. The connector terminal of claim 1, further comprising:

an inner wall forming a lumen that extends along the length of the connector terminal and within the second contact member, the lumen having a proximal opening in proximity to the first contact member, the inner wall isolating the lumen from the switching assembly and the aforementioned electrical couplings to the multiplexer, and at least a portion of the inner wall being formed by a tubing member;

wherein each ferrule of the proximal and distal feedthrough assemblies includes a longitudinally extending thru-hole, the thru-holes being approximately longitudinally aligned with one another; and

the tubing member is mounted within each thru-hole and extends within the second contact member between the ferrules.

6. The connector terminal of claim 5, wherein:

the switching assembly further comprises a flex circuit, the flex circuit including a plurality of contact/bond pads, a plurality of connection junctions and a pair of contoured slots, one formed in each end of the flex circuit;

the plurality of contact/bond pads being coupled to the multiplexer and to a corresponding connection junction by a conductive trace;

each of the plurality of connection junctions being coupled to a corresponding one of the plurality of distal feedthrough pins, proximal feedthrough pins and second connector contact; and

each contoured slot being fitted about the tubing member such that each end of the flex circuit is bent inward.

7. The connector terminal of claim 1, wherein:

the switching assembly further comprises a ceramic insulator substrate including contact/bond pads formed on a exterior surface thereof and conductive vias formed therein, each via coupling one of the contact/bond pads to a corresponding one of the feedthrough pins and second contact member; and

the integrated circuit chip is supported by the ceramic insulator substrate and coupled to the external contact/bond pads thereof.

8. The connector terminal of claim 1, wherein:

the switching assembly further comprises a package, which is contained within the second contact member and which encloses the integrated circuit chip, the package including ceramic sidewalls, conductive interconnect members formed on an exterior surface of at least one of the ceramic sidewalls, and conductive vias, each via electrically connecting the integrated circuit chip to the conductive interconnect members; and

each of the distal feedthrough pins and the proximal feedthrough pin is coupled to a corresponding one of the conductive interconnect members.

9. The connector terminal of claim 8, wherein the package further includes at least one titanium sidewall.

10. The connector terminal of claim 1, wherein each insulator of the proximal and distal feedthrough subassemblies is formed of LaBor 4 glass.

11. The connector terminal of claim 1, wherein:

each ferrule of the proximal and distal feedthrough subassemblies is formed of MP35N alloy;

each feedthrough pin of the proximal and distal feedthrough subassemblies is formed of one of;

Ta and Nb; and

each insulator of the proximal and distal feedthrough subassemblies is formed of Ta-23 glass.