Method of locating the tip of a central venous catheter

• US 8,512,256 B2
• Filed: 09/09/2010
• Issued: 08/20/2013
• Est. Priority Date: 10/23/2006
• Status: Active Grant

• Current Assignee: BARD Access Systems Incorporated (Becton, Dickinson & Co)
• Original Assignee: BARD Access Systems Incorporated (Becton, Dickinson & Co)
• Inventors: Rothenberg, Peter M.
• Primary Examiner(s): Patel, Niketa
• Assistant Examiner(s): LEVICKY, WILLIAM J
• Application Number:
  US12/878,915
• Publication Number:
  US 20100331712A1
• Time in Patent Office: 1,076 Days
• Field of Search: 600/508, 600/509, 600/510, 600/424, 607/28, 607/122
• US Class Current: 600/508
• CPC Class Codes: A61B 5/06 Devices, other than using radiation, for detecting or locating foreign bodies for removing same A61B17/50 ; determining position of probes within or on the body of the patient
• CPC Class Codes: A61B 5/061 Determining position of a probe within the body employing means separate from the probe, e.g. sensing internal probe position employing impedance electrodes on the surface of the body A61B1/00158 takes precedence
• CPC Class Codes: A61B 5/065 Determining position of the probe employing exclusively positioning means located on or in the probe, e.g. using position sensors arranged on the probe
• CPC Class Codes: A61B 5/287 Holders for multiple electrodes, e.g. electrode catheters for electrophysiological study [EPS]
• CPC Class Codes: A61B 5/349 Detecting specific parameters of the electrocardiograph cycle
• CPC Class Codes: A61B 5/353 Detecting P-waves
• CPC Class Codes: A61B 5/6852 Catheters

Abstract

A method of locating a tip of a central venous catheter (“CVC”) having a distal and proximal pair of electrodes disposed within the superior vena cava, right atrium, and/or right ventricle. The method includes obtaining a distal and proximal electrical signal from the distal and proximal pair of electrodes and using those signals to generate a distal and proximal P wave, respectively. A deflection value is determined for each of the P waves. A ratio of the deflection values is then used to determine a location of the tip of the CVC. Optionally, the CVC may include a reference pair of electrodes disposed within the superior vena cava from which a reference deflection value may be obtained. A ratio of one of the other deflection values to the reference deflection value may be used to determine the location of the tip of the CVC.

Claims

1. A method of locating a tip of a central venous catheter having a portion disposed within the superior vena cava, the catheter comprising a distal pair of electrodes and a proximal pair of electrodes spaced longitudinally from the distal pair of electrodes, the method comprising:

obtaining a distal electrical signal from the distal pair of electrodes;

generating a first P wave from the distal signal;

obtaining a proximal electrical signal from the proximal pair of electrodes;

generating a second P wave from the proximal signal;

comparing the first and second P waves;

obtaining a reference electrical signal in the superior vena cava;

generating a reference P wave from the reference electrical signal;

comparing the reference P wave with at least one of the first and second P waves; and

determining a location of the tip of the central venous catheter based on the comparison of the first and second P waves and the comparison of the reference P wave with at least one of the first and second P waves.

2. The method according to claim 1, wherein the first P wave has a first shape, the second P wave has a second shape, and the reference P wave has a reference shape, comparing the first and second P waves comprising comparing the first and second shapes, and comparing the reference P wave with at least one of the first and second P waves comprising comparing the reference shape with at least one of the first and second shapes.

3. The method according to claim 2, wherein the first shape has a first height and the second shape has a second height, determining the location of the tip of the central venous catheter based on the comparison of the first and second P waves and the comparison of the reference P wave with at least one of the first and second P waves comprising concluding the tip of the central venous catheter is located in the right atrium when the first height is at least twice the second height.

4. The method according to claim 2, wherein the first shape has a first height and the second shape has a second height, determining the location of the tip of the central venous catheter based on the comparison of the first and second P waves and the comparison of the reference P wave with at least one of the first and second P waves comprising concluding the tip of the central venous catheter is located in the right ventricle when the first height is at most half the second height.

5. The method according to claim 2, wherein the first shape has a first height, the second shape has a second height, and the reference shape has a reference height, determining the location of the tip of the central venous catheter based on the comparison of the first and second P waves and the comparison of the reference P wave with at least one of the first and second P waves comprising:

concluding the tip of the central venous catheter is located in the superior vena cava when the first height is approximately equal to both the second height and the reference height; and

concluding the tip of the central venous catheter is located in the right atrium when the first height is approximately equal to the second height and greater than the reference height.

6. The method according to claim 2, wherein determining the location of the tip of the central venous catheter based on the comparison of the first and second P waves and the comparison of the reference P wave with at least one of the first and second P waves comprises concluding the tip of the central venous catheter is located in the right ventricle when the first shape approximates a mirror image of the reference shape about a horizontal axis.

7. The method according to claim 2, wherein the first shape has a first height and the reference shape has a reference height, determining the location of the tip of the central venous catheter based on the comparison of the first and second P waves and the comparison of the reference P wave with at least one of the first and second P waves comprising concluding the tip of the central venous catheter is located in the right atrium when the first height is at least twice the reference height.

8. The method according to claim 2, wherein the first shape has a first height, the second shape has a second height, and the reference shape has a reference height, determining the location of the tip of the central venous catheter based on the comparison of the first and second P waves and the comparison of the reference P wave with at least one of the first and second P waves comprising:

concluding the tip of the central venous catheter is located in the superior vena cava when the first height is approximately equal to both the second height and the reference height; and

concluding the tip of the central venous catheter is located in the right ventricle when the first height is approximately equal to the reference height and is less than the second height.

9. The method according to claim 2, wherein the second shape has a second height and the reference shape has a reference height, determining the location of the tip of the central venous catheter based on the comparison of the first and second P waves and the comparison of the reference P wave with at least one of the first and second P waves comprising concluding the tip of the central venous catheter is located in the right atrium or right ventricle when the second height is at least twice the reference height.

10. The method according to claim 2, wherein the first shape has a first height, the second shape has a second height, and the reference shape has a reference height, determining the location of the tip of the central venous catheter based on the comparison of the first and second P waves and the comparison of the reference P wave with at least one of the first and second P waves comprising:

concluding the tip of the central venous catheter is located in the superior vena cava when the second height is approximately equal to both the first height and the reference height; and

concluding the tip of the central venous catheter is located in the right atrium when the second height is approximately equal to the reference height and is less than the first height.

11. The method according to claim 1, wherein the portion of the central venous catheter disposed within the superior vena cava includes a reference pair of electrodes, obtaining the reference electrical signal in the superior vena cava comprising obtaining the reference electrical signal from the reference pair of electrodes.