Pen-type injector

• US 8,512,297 B2
• Filed: 03/03/2011
• Issued: 08/20/2013
• Est. Priority Date: 03/03/2003
• Status: Active Grant

• Current Assignee: Sanofi-Aventis Deutschland GmbH (Sanofi )
• Original Assignee: Sanofi-Aventis Deutschland GmbH (Sanofi )
• Inventors: Veasey, Robert Frederick, Perkins, Robert, Plumptre, David Aubrey
• Primary Examiner(s): MENDEZ, MANUEL A
• Application Number:
  US13/040,198
• Publication Number:
  US 20110152784A1
• Time in Patent Office: 901 Days
• Field of Search: 604/187, 604207-211, 604/218, 604/221, 604/224, 604/232
• US Class Current: 604/209
• CPC Class Codes: A61M 2005/2407 from the rear
• CPC Class Codes: A61M 2005/3126 Specific display means related to dosing
• CPC Class Codes: A61M 2205/581 by audible feedback
• CPC Class Codes: A61M 2205/582 by tactile feedback
• CPC Class Codes: A61M 5/24 Ampoule syringes, i.e. syringes with needle for use in combination with replaceable ampoules or carpules, e.g. automatic ampoules or carpules A61J1/06
• CPC Class Codes: A61M 5/31528 by means of rotational movements, e.g. screw-thread mechanisms
• CPC Class Codes: A61M 5/31533 Dosing mechanisms, i.e. setting a dose administrating mechanisms A61M5/31565
• CPC Class Codes: A61M 5/31535 Means improving security or handling thereof, e.g. blocking means, means preventing insufficient dosing, means allowing correction of overset dose
• CPC Class Codes: A61M 5/31536 Blocking means to immobilize a selected dose, e.g. to administer equal doses
• CPC Class Codes: A61M 5/31541 Means preventing setting of a dose beyond the amount remaining in the cartridge
• CPC Class Codes: A61M 5/31546 Electrically operated dose setting, e.g. input via touch screen or plus/minus buttons
• CPC Class Codes: A61M 5/31551 including axial movement of dose setting member
• CPC Class Codes: A61M 5/3156 using volume steps only adjustable in discrete intervals, i.e. individually distinct intervals
• CPC Class Codes: A61M 5/31563 interacting with a displaceable stop member
• CPC Class Codes: A61M 5/31565 Administration mechanisms, i.e. constructional features, modes of administering a dose dosing mechanisms for setting a dose A61M5/31533
• CPC Class Codes: A61M 5/31568 Means keeping track of the total dose administered, e.g. since the cartridge was inserted
• CPC Class Codes: A61M 5/3157 Means providing feedback signals when administration is completed A61M5/20 takes precedence
• CPC Class Codes: A61M 5/31575 using scaling up or down transmissions, e.g. gearbox
• CPC Class Codes: A61M 5/31578 based on axial translation, i.e. components directly operatively associated and axially moved with plunger rod
• CPC Class Codes: A61M 5/31585 performed by axially moving actuator, e.g. an injection button
• CPC Class Codes: A61M 5/31593 : Multi-dose, i.e. individually set dose repeatedly administered from the same medicament reservoir
• CPC Class Codes: A61M 5/32 : Needles; Details of needles pertaining to their connection with syringe or hub infusion needles A61M5/158; Accessories for bringing the needle into, or holding the needle on, the body A61M5/42, A61M5/46 take precedence; guide needles for catheters A61M25/065; Devices for protection of needles apparatus specially adapted for cleaning or sterilising needles A61M5/001

Abstract

The present invention relates to injectors, such as pen-type injectors, that provide for administration of medicinal products from a multidose-cartridge and permit a user to set the delivery dose. The injector may include a housing, a piston rod adapted to operate through the housing, a dose dial sleeve located between the housing and the piston rod, and a drive sleeve located between the dose dial sleeve and the piston rod. The dose dial sleeve may have a helical thread of first lead and the drive sleeve may have a helical groove of second lead. The first lead of the helical thread and the second lead of the helical groove may be the same.

Claims

1. A dispensed dose indicator mechanism for a pen-type injector, comprising:

a housing having an internal surface with one or more splines;

a drive sleeve configured to move both axially and rotationally relative to the internal surface of the housing, the drive sleeve having an outer surface on which a thread is disposed; and

a nut engaged with the thread, where the nut is fixed rotationally with respect to the housing and is axially displaceable along the thread when the drive sleeve is rotated.

2. The dispensed dose indicator mechanism of claim 1 further characterized in that the outer surface of the drive sleeve has a first radially extending flange and a second radially extending flange, the thread is disposed between the two flanges.

3. The dispensed dose indicator mechanism of claim 1 where the nut is keyed to the one or more splines on the internal surface of the housing to prevent the nut from rotating relative to the housing while allowing axial movement relative to the housing.

4. The dispensed dose indicator mechanism of claim 1 where the nut is a half nut.

5. The dispensed dose indicator mechanism of claim 1 where axially displacement of the nut is indicative of dispensed doses.

6. The dispensed dose indicator mechanism of claim 1 where the thread is proportional to available doses of medicament contained in a cartridge attached to the pen-type injector.

7. The dispensed dose indicator mechanism of claim 1 where a first radial stop on the nut engages a second radial stop on the second flange when a final dose of medicament is dispensed from a cartridge attached to the pen-type injector.

8. The dispensed dose indicator mechanism of claim 1 where a radial stop on the nut engages a radial stop on the first flange indicative of a cartridge full position.