Sterile blood separating system
First Claim
Patent Images
1. A system for separating components of a composition according to density comprising:
- a torque generating device;
a separation device for separating the composition into different components according to density, the separation device including;
a first end and a second end opposite to the first end, wherein a longitudinal axis extends between the first end and the second end;
a sidewall extending between the first end and the second end, the sidewall defining a separation chamber;
a separator within the separation chamber along the longitudinal axis;
an inlet port and an outlet port each extending through the sidewall between the first end and the second end; and
a counterbalance between the second end and the inlet port; and
a housing that accommodates the separation device to maintain the separation device in a sterile condition when seated therein;
wherein the torque generating device is external to the housing and is configured to supply torque to the separation device when seated in the housing.
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Abstract
A system for separating components of a composition according to density. The system includes a torque generating device, a separation device, and a housing. The separation device separates the composition into different components according to density. The housing accommodates the separation device. The housing includes a base having an interface that transfers torque from the torque generating device to the separation device, a cover, and a conduit for introducing the composition into the separation device without opening the cover.
230 Citations
20 Claims
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1. A system for separating components of a composition according to density comprising:
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a torque generating device; a separation device for separating the composition into different components according to density, the separation device including; a first end and a second end opposite to the first end, wherein a longitudinal axis extends between the first end and the second end; a sidewall extending between the first end and the second end, the sidewall defining a separation chamber; a separator within the separation chamber along the longitudinal axis; an inlet port and an outlet port each extending through the sidewall between the first end and the second end; and a counterbalance between the second end and the inlet port; and a housing that accommodates the separation device to maintain the separation device in a sterile condition when seated therein; wherein the torque generating device is external to the housing and is configured to supply torque to the separation device when seated in the housing. - View Dependent Claims (2, 3, 9, 10, 11, 12, 13, 14)
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4. A separation device for separating components of a composition according to density comprising:
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a first end, a second end, a sidewall that extends between the first end and the second end to define a separation chamber, wherein a longitudinal axis extends through the separation chamber between the first end and the second end; a separator slidably mounted within the separation chamber along the longitudinal axis and having a density such that the separator is operable to move to an equilibrium between two of the components to be separated after the separation device is rotated; a first outlet port including a first outlet tube that extends from a first side of the sidewall and through the buoy to provide fluid communication between an exterior of the separation device and a first area of the separation chamber between the separator and the second end; a second outlet port including a second outlet tube that extends from the first side of the sidewall to a second area of the separation chamber that is between the first end and the buoy separator; and a coupling device at a second side of the sidewall that is opposite to the first side of the sidewall surface, the coupling device is configured to receive torque generated by a torque generating device; wherein upon rotation of the separation device about a midpoint between the first end and the second end along the longitudinal axis in a plane that is perpendicular to a longitudinal axis along which the torque is applied, the separator is operable to separate a first component of the composition having a first density from a second component of the composition having a second density, the first component is isolated in the first area of the separation chamber and the second component is isolated in the second area of the separation chamber. - View Dependent Claims (5, 6, 7)
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8. A device for separating components of a composition according to density comprising:
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a separation device including; a first end, a second end opposite to the first end, a cylindrical sidewall extending between the first end and the second end to define a separation chamber, and a longitudinal axis extending through an axial center of the separation chamber from the first end to the second end; a counter-balance within the separation chamber and proximate to the first end; a separator including a buoy within the separation chamber and slidably mounted along the longitudinal axis between the second end and the counter-balance; a divider mounted to the buoy at a side of the buoy proximate to the second end, the buoy has a density such that it is operable to move to an equilibrium between two of the components to be separated; a first outlet port including a first outlet tube that extends from a first side of the sidewall to the divider, the first outlet tube extends through the buoy; a second outlet port including a second outlet tube that extends from the first side of the sidewall to a location within the separation chamber that is between the counter-balance and the buoy; an inlet port that provides fluid communication between an exterior of the separation device and the separation chamber, the inlet port is at the first side of the sidewall and spaced apart from the first and second outlet ports; and a locking device at a second side of the sidewall that is opposite to the first side and is operable to cooperate with a rotating platform to rotate the separation device; and an outer housing including a base and a sidewall that define a receptacle that accommodates the separation device and includes an interface operable to transfer torque from the rotating platform to the separation device when the separation device is seated in the receptacle; a cover configured to engage the outer housing to provide a seal therebetween and maintain the separation device in a sterile condition when seated within the receptacle, the cover includes a conduit extending therethrough, the conduit is operable to cooperate with the inlet port when the separation device is seated in the receptacle to permit introduction of the composition through the cover and into the separation device through the inlet port while the separation device is maintained in a sterile condition; wherein the rotating platform is external to the outer housing and is selectively coupled to the outer housing at the interface to supply torque to the separation device; and wherein upon rotation of the separation device by the rotating platform about a midpoint between the first end and the second end along the longitudinal axis in a plane that is perpendicular to a longitudinal axis along which the torque is applied and restricting rotation of the separation device about the longitudinal axis, the separator is operable to separate a first component of the composition having a first density from a second component of the composition having a second density, the first component is separated in a first area of the separation chamber between the divider and the first end and the second component is separated in a second area of the separation chamber between the divider and the second end.
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15. A system for separating components of a composition according to density comprising:
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A separation device including; A first end and a second end opposite to the first end, wherein a first longitudinal axis extends between the first end and the second end; A sidewall extending between the first end and the second end, the sidewall defining a separation chamber; A movable buoy within the separation chamber for separating components of the composition according to density; and An inlet port and an outlet port each extending through the sidewall between the first end and the second end; A housing including a base, a housing sidewall extending from the base, and a cover, the housing defines a compartment configured to receive the separation device therein such that the first longitudinal axis is substantially parallel to the base, and maintain the separation device in a sterile condition; and A torque generating device external to the housing and selectively coupled to the housing to transfer torque to the separation device when seated in the compartment to rotate the separation device about a midpoint between the first end and the second end along the first longitudinal axis in a plane that is both substantially perpendicular to a second longitudinal axis along which the torque is applied and substantially parallel to the base. - View Dependent Claims (16, 17, 18, 19, 20)
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Specification