Oral care products comprising buffer systems for improved mineralization/remineralization benefits

• US 8,518,383 B2
• Filed: 02/02/2007
• Issued: 08/27/2013
• Est. Priority Date: 02/03/2006
• Status: Active Grant

• Current Assignee: WM Wrigley Jr Company (Mars Incorporated)
• Original Assignee: WM Wrigley Jr Company (Mars Incorporated)
• Inventors: Haas, Michael S.
• Primary Examiner(s): Krass, Frederick
• Assistant Examiner(s): Cohen, Michael P
• Application Number:
  US11/670,737
• Publication Number:
  US 20080050407A1
• Time in Patent Office: 2,398 Days
• Field of Search: 424/440
• US Class Current: 424/57
• CPC Class Codes: A23G 3/362 containing inorganic compounds
• CPC Class Codes: A23G 3/54 Composite products, e.g. layered, coated, filled
• CPC Class Codes: A23G 4/064 containing inorganic compounds
• CPC Class Codes: A23G 4/20 Composite products, e.g. centre-filled , multi-layer, laminated
• CPC Class Codes: A23P 10/30 Encapsulation of particles, e.g. foodstuff additives
• CPC Class Codes: A23V 2002/00 Food compositions, function of food ingredients or processes for food or foodstuffs
• CPC Class Codes: A23V 2200/312 having an effect on dental health
• CPC Class Codes: A23V 2250/1578 Calcium
• CPC Class Codes: A23V 2250/16 Potassium
• CPC Class Codes: A61K 8/0216 Solid or semisolid forms
• CPC Class Codes: A61K 8/24 Phosphorous; Compounds thereof
• CPC Class Codes: A61K 8/36 Carboxylic acids; Salts or anhydrides thereof
• CPC Class Codes: A61K 8/362 Polycarboxylic acids
• CPC Class Codes: A61K 8/365 Hydroxycarboxylic acids; Ketocarboxylic acids
• CPC Class Codes: A61K 8/44 Aminocarboxylic acids or derivatives thereof, e.g. aminocarboxylic acids containing sulfur; Salts; Esters or N-acylated derivatives thereof
• CPC Class Codes: A61K 8/602 Glycosides, e.g. rutin
• CPC Class Codes: A61K 8/676 Ascorbic acid, i.e. vitamin C
• CPC Class Codes: A61K 8/733 Alginic acid; Salts thereof
• CPC Class Codes: A61K 8/88 Polyamides
• CPC Class Codes: A61P 1/02 Stomatological preparations, e.g. drugs for caries, aphtae, periodontitis
• CPC Class Codes: A61Q 11/00 : Preparations for care of the teeth, of the oral cavity or of dentures; Dentifrices, e.g. toothpastes; Mouth rinses

Abstract

Oral products for the improved mineralization/remineralization of teeth are provided. In an embodiment, the present disclosure provides an oral product comprising a calcium salt, a phosphate salt, a sodium salt and a potassium salt. For example, the molar ratio of the sodium salt to the potassium salt ranges from about 3 to about 4.

Claims

1. An oral product comprising:

calcium citrate; and

a sodium phosphate salt and a potassium phosphate salt, wherein the phosphate salts are encapsulated together in a molar ratio of sodium phosphate salt to potassium phosphate salt ranging from about 3 to about 4, and wherein the oral product releases the calcium citrate and the phosphate salts in a molar ratio of about 1.5 to about 2.0.

2. The oral product of claim 1, wherein the sodium phosphate salt and the potassium phosphate salt are encapsulated in a polyvinyl acetate, the polyvinyl acetate to phosphate salts weight ratio in the oral product being from about 10:

90 to about 90;

10.

3. The oral product of claim 1, wherein the total amount of the sodium phosphate salt and the potassium phosphate salt comprises from about 0.01% to about 10.0% by weight of the oral product.

4. The oral product of claim 1, wherein the oral product is selected from the group consisting of pressed tablets, chewy candies, hard boiled candies, mints, chocolates, nougats, gels and confectionary pastes.

5. A chewing gum comprising:

calcium citrate;

a sodium phosphate salt; and

a potassium phosphate salt, wherein the molar ratio of the sodium phosphate salt to the potassium phosphate salt ranges from about 3 to about 4, and wherein the chewing gum releases the calcium citrate and the phosphate salts in a molar ratio of about 1.5 to about 2.0.

6. The chewing gum of claim 5, wherein the sodium phosphate salt and potassium phosphate salt comprise a form selected from the group consisting of encapsulated, agglomerated, fixated, entrapped and combinations thereof.

7. The chewing gum of claim 5, comprising a polymer that encapsulates the sodium phosphate salt and potassium phosphate salt having a molecular weight of about 1.5×

10³ g/mol to about 150×

10³ g/mol.

8. The chewing gum of claim 7, wherein the polymer to phosphate salts weight ratio in the chewing gum is about 10:

90 to about 90;

10.

9. The chewing gum of claim 5, wherein the chewing gum comprises a coating.

10. The chewing gum of claim 9, wherein the coating comprises the sodium phosphate salt and the potassium phosphate salt.

11. The chewing gum of claim 5, wherein the chewing gum comprises at least two layers, wherein one layer comprises the calcium salt and another layer comprises the sodium phosphate salt and the potassium phosphate salt.

12. The chewing gum of claim 5, wherein the chewing gum comprises at least three layers, wherein one layer comprises the calcium salt, another layer comprises the sodium phosphate salt and another layer comprises the potassium phosphate salt.

13. The chewing gum of claim 5, wherein a blend of the sodium phosphate compound and the potassium phosphate compound are encapsulated in a polyvinyl acetate.

14. The chewing gum of claim 5, wherein the total amount of the sodium phosphate compound and the potassium phosphate compound comprises about 0.01-10.0% by weight of the chewing gum.

15. The chewing gum of claim 5, wherein the calcium salt comprises from about 1.0% to about 10.0% by weight of the chewing gum.

16. The chewing gum of claim 5, wherein the chewing gum is a sugarless chewing gum.

17. A chewing gum comprising:

a chewing gum shell, the chewing gum shell comprising calcium citrate; and

a liquid center surrounded by the chewing gum shell, the liquid center comprising a sodium phosphate salt and a potassium phosphate salt, wherein the molar ratio of the sodium phosphate salt to the potassium phosphate salt ranges from about 3 to about 4, and wherein the chewing gum releases the calcium citrate and the phosphate salts in a molar ratio of about 1.5 to about 2.0.

18. The chewing gum of claim 17, wherein the sodium phosphate salt and potassium salt phosphate comprise a foam selected from the group consisting of encapsulated, agglomerated, fixated, entrapped and combinations thereof.

19. A method for remineralizing teeth of a consumer, the method comprising:

providing an oral product comprising calcium citrate, a sodium phosphate salt and a potassium phosphate salt, wherein the molar ratio of the sodium phosphate salt to the potassium phosphate salt ranges from about 3 to about 4, and wherein the oral product releases the calcium citrate and the phosphate salts in a molar ratio of about 1.5 to about 2.0; and

administering the oral product into an oral cavity of the consumer.

20. The method of claim 19, wherein the oral product comprises a chewing gum.

21. The method of claim 20, wherein the method further comprises chewing the chewing gum for at least 5 minutes.