Methods of repairing an abnormal mitral valve

• US 8,529,621 B2
• Filed: 03/09/2012
• Issued: 09/10/2013
• Est. Priority Date: 05/17/2001
• Status: Expired due to Term

• Current Assignee: Edwards Lifesciences Corporation
• Original Assignee: Edwards Lifesciences Corporation
• Inventors: Alfieri, Ottavio, Maisano, Francesco, Redaelli, Alberto
• Primary Examiner(s): Sweet, Thomas J
• Assistant Examiner(s): Prone, Christopher D
• Application Number:
  US13/416,929
• Publication Number:
  US 20120172983A1
• Time in Patent Office: 550 Days
• Field of Search: 623/1.26, 623/2.1, 623/2.36, 623/2.37, 623/2.38, 623/2.11
• US Class Current: 623/2.36
• CPC Class Codes: A61F 2/2448 D-shaped rings

Abstract

The present invention refers to an annular prosthesis for mitral valve. In one of its embodiments the annular prosthesis for mitral valve is made up of a posterior half-ring and an anterior half-ring coupled to each other on a first transverse plane which defines a maximum width section of the prosthesis, characterized in that the ratio between the distance between said anterior half-ring and said posterior half-ring, as measured along a second plane, perpendicular to said first plane and equidistant to said couplings, and said maximum width of the prosthesis is lower than ¾.

Claims

1. A method of correcting the functionality of a patient'"'"'s mitral valve in a mitral annulus having an anterior leaflet and a posterior leaflet, comprising:

providing an annular prosthetic ring made of a material that can substantially maintain an implanted shape defining a curved posterior section contiguous with a generally rectilinear anterior section and together forming a periphery oriented around a central flow axis, wherein in plan view as seen along the flow axis the prosthetic ring has a transverse plane that defines a maximum width representing an identifying size parameter of the prosthetic ring corresponding to the dimension of the base of the patient'"'"'s anterior leaflet in systole, and a longitudinal plane perpendicular to the transverse plane that bisects the anterior and posterior sections, the prosthetic ring having a height from the anterior section to the posterior section along the longitudinal plane; and

implanting the prosthetic ring at the patient'"'"'s mitral valve such that the curved posterior section lies along the mitral annulus at the base of the posterior leaflet and the generally rectilinear anterior section lies along the mitral annulus at the base of the anterior leaflet;

wherein the prosthetic ring has a reduced height to maximum width ratio relative to a normal height to width ratio found in the annulus of natural valves free of pathology so that when implanted the prosthetic ring squeezes the mitral annulus along the longitudinal axis such that the posterior valve leaflet and anterior valve leaflet move toward each other relative to their normal spacing as found in a natural valve free of pathology while the mitral annulus in the transverse direction and the maximum width of the prosthetic ring remain substantially unchanged.

2. The method of claim 1, wherein the prosthetic ring is symmetrical across the longitudinal plane.

3. The method of claim 1, wherein the prosthetic ring is asymmetrical across the longitudinal plane.

4. The method of claim 3, wherein the curved posterior section on one side of the longitudinal plane has a radius of curvature that is smaller than on the other side of the longitudinal plane.

5. The method of claim 1, wherein the curved posterior section and generally rectilinear anterior section of the prosthetic ring together form a generally D-shaped periphery.

6. The method of claim 1, wherein the prosthetic ring has a height to maximum width ratio that is equal to 2.5/4.

7. The method of claim 1, wherein the prosthetic ring has a height to maximum width ratio is equal to 2/4.

8. A method of correcting the functionality of a patient'"'"'s mitral valve in a mitral annulus having an anterior leaflet and a posterior leaflet, the mitral annulus having a transverse dimension in systole along the base of the patient'"'"'s anterior leaflet and a longitudinal dimension perpendicular to the transverse dimension and between the bases of the two leaflets, the method comprising:

selecting an annular prosthetic ring from a choice of prosthetic rings made of a material that can substantially maintain an implanted shape, the prosthetic ring selected having an identifying size corresponding to the transverse dimension of the mitral annulus, wherein each prosthetic ring defines a posterior section contiguous with an anterior section and forming a periphery oriented around a central flow axis, wherein in plan view as seen along the flow axis the prosthetic ring has a maximum width dimension along a major axis perpendicular to a height dimension along a minor axis that bisects the anterior and posterior sections, wherein the maximum width dimension is approximately equal to the transverse dimension; and

implanting the prosthetic ring at the patient'"'"'s mitral valve such that the curved posterior section lies along the mitral annulus at the base of the posterior valve leaflet and the generally rectilinear anterior section lies along the mitral annulus at the base of the anterior valve leaflet;

wherein the prosthetic ring has a reduced height dimension to maximum width dimension ratio relative to a normal height to width ratio found in the annulus of natural valves free of pathology so that when implanted the prosthetic ring reduces the longitudinal dimension such that the posterior valve leaflet and anterior valve leaflet move toward each other relative to their normal spacing as found in a natural valve free of pathology while the transverse dimension of the annulus and the maximum width of the prosthetic ring remain unchanged.

9. The method of claim 8, wherein the prosthetic ring is symmetrical across the minor axis.

10. The method of claim 8, wherein the prosthetic ring is asymmetrical across the minor axis.

11. The method of claim 10, wherein the curved posterior section on one side of the minor axis has a radius of curvature that is smaller than on the other side of the minor axis.

12. The method of claim 8, wherein the prosthetic ring has a height dimension to maximum width dimension ratio that is equal to 2.5/4.

13. The method of claim 8, wherein the prosthetic ring has a height dimension to maximum width dimension ratio is equal to 2/4.

14. A method of correcting the functionality of a patient'"'"'s mitral valve having an annulus, an anterior leaflet and a posterior leaflet, comprising implanting a prosthetic ring made of a material that can substantially maintain an implanted shape at the patient'"'"'s mitral valve such that when implanted, the prosthetic ring squeezes the mitral annulus along the longitudinal axis relative its normal shape as found in a natural valve free of pathology such that the posterior valve leaflet and anterior valve leaflet move toward each other relative to their normal spacing as found in a natural valve free of pathology while the mitral annulus in the transverse direction and the maximum width of the prosthetic ring remain substantially unchanged.

15. The method of claim 14, wherein the annular prosthetic ring defines a periphery oriented around a central flow axis, wherein in plan view as seen along the flow axis the prosthetic ring has a maximum width dimension along a major axis perpendicular to a minor axis that bisects the anterior and posterior sections, and the method includes implanting the prosthetic ring at the patient'"'"'s mitral valve such that the maximum width dimension is parallel to the base of the anterior valve leaflet.

16. The method of claim 15, wherein the prosthetic ring is symmetrical across the minor axis.

17. The method of claim 15, wherein the prosthetic ring is asymmetrical across the minor axis.

18. The method of claim 17, wherein the curved posterior section on one side of the minor axis has a radius of curvature that is smaller than on the other side of the minor axis.

19. The method of claim 15, wherein the prosthetic ring has a height dimension along the minor axis and the ratio of the height dimension to maximum width dimension is equal to 2.5/4.

20. The method of claim 15, wherein the prosthetic ring has a height dimension along the minor axis and the ratio of the height dimension to maximum width dimension is equal to 2/4.