Blood/air mass exchange apparatus
First Claim
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1. A mass exchange apparatus for use in blood/air mass exchange comprising:
- (a) plural blood flow conduits for defining a blood flow from a blood flow inlet provided thereto;
(b) plural air flow conduits for defining an air flow from an air flow inlet provided thereto;
(c) plural fluid flow feeds comprising a carbon dioxide feed and either;
an air feed;
oran oxygen feed and an inert gas feed;
(d) a sensor for sensing patient respiratory demand; and
(e) a controller for controlling the rate of blood/air mass exchange by separate control of the levels of carbon dioxide and oxygen in the air flow responsive to the sensing of patient respiratory demand by the sensor wherein the controller is configured to maintain the partial pressure of carbon dioxide in the air flow above a level of 4 kPa.
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Abstract
There is provided a mass exchange apparatus (114) for use in blood/air mass exchange comprising plural blood flow conduits for defining a blood flow from a blood flow inlet provided thereto; and plural air flow conduits for defining an air flow from an air flow inlet provided thereto. The plural air flow conduits and plural blood flow conduits at least partially comprise gas-permeable membrane material, and the conduits are arranged relative to each other such as to enable transfer of oxygen from the air flow to the blood flow and transfer of carbon dioxide from the blood flow to the air flow through the membrane material.
22 Citations
62 Claims
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1. A mass exchange apparatus for use in blood/air mass exchange comprising:
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(a) plural blood flow conduits for defining a blood flow from a blood flow inlet provided thereto; (b) plural air flow conduits for defining an air flow from an air flow inlet provided thereto; (c) plural fluid flow feeds comprising a carbon dioxide feed and either; an air feed;
oran oxygen feed and an inert gas feed; (d) a sensor for sensing patient respiratory demand; and (e) a controller for controlling the rate of blood/air mass exchange by separate control of the levels of carbon dioxide and oxygen in the air flow responsive to the sensing of patient respiratory demand by the sensor wherein the controller is configured to maintain the partial pressure of carbon dioxide in the air flow above a level of 4 kPa. - View Dependent Claims (2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 16, 17, 18, 19, 20, 21, 22, 23, 24, 25, 26, 27, 28, 29, 30, 31, 32, 33, 34, 35, 36, 37, 38, 39)
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40. A mixed-flow mass exchange apparatus for use in mass exchange comprising;
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(a) plural blood flow conduits for defining a blood flow from a blood flow inlet to a blood flow outlet provided thereto; and (b) plural air flow conduits for defining an air flow from an air flow inlet to an air flow outlet provided thereto; wherein said plural blood flow conduits and said plural airflow conduits at least partially comprise gas-permeable membrane material, and the conduits are arranged relative to each other such as to enable transfer of carbon dioxide from said blood flow to said air flow and transfer of oxygen from the air flow to the blood flow through said membrane material; and wherein said apparatus additionally comprises an adjuster that enables independent adjustment of the concentration of the carbon dioxide and oxygen in the blood flow, and wherein the adjuster is configured to maintain the partial pressure of carbon dioxide in the air flow above a level of 4 kPa. - View Dependent Claims (41, 42, 43, 44, 45, 46, 47, 48, 49, 50, 51, 52, 53, 54, 55, 56, 57)
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58. A mixed-flow mass exchange apparatus for use in mass exchange comprising:
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(a) plural blood flow conduits for defining a blood flow from a blood flow inlet to a blood flow outlet provided thereto; and (b) plural air flow conduits for defining an air flow from an air flow inlet to an air flow outlet provided thereto; wherein said plural blood flow conduits and said plural airflow conduits at least partially comprise gas-permeable membrane material, and the conduits are arranged relative to each other such as to enable transfer of carbon dioxide from said blood flow to said air flow and transfer of oxygen from the air flow to the blood flow through said membrane material, and wherein said apparatus additionally comprises an adjuster that enables independent adjustment of the concentration of the carbon dioxide and oxygen in the blood flow; wherein the adjuster comprises a flow selector configured to select the relative flow pattern of the blood flow and the air flow; wherein said flow selector comprises a multi-way valve; wherein an airflow inlet multi-way valve enables separation of the air flow into plural separate airflows for directing to plural separate air flow inlets of the plural airflow conduits. - View Dependent Claims (59)
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60. A mixed-flow mass exchange apparatus for use in mass exchange comprising;
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(a) plural blood flow conduits for defining a blood flow from a blood flow inlet to a blood flow outlet provided thereto; and (b) plural air flow conduits for defining an air flow from an air flow inlet to an air flow outlet provided thereto; wherein said plural blood flow conduits and said plural airflow conduits at least partially comprise gas-permeable membrane material, and the conduits are arranged relative to each other such as to enable transfer of carbon dioxide from said blood flow to said air flow and transfer of oxygen from the air flow to the blood flow through said membrane material; and wherein said apparatus additionally comprises an adjuster that enables independent adjustment of the concentration of the carbon dioxide and oxygen in the blood flow; wherein the adjuster comprises a flow selector configured to select the relative flow pattern of the blood flow and the air flow; and wherein said flow selector comprises a multi-way valve; wherein an air flow outlet multi-way valve enables separation of the air flow into plural separate air flows for directing from plural separate outlets of the plural air flow conduits.
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61. A mixed-flow mass exchange apparatus for use in mass exchange comprising;
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(a) plural blood flow conduits for defining a blood flow from a blood flow inlet to a blood flow outlet provided thereto; and (b) plural air flow conduits for defining an air flow from an air flow inlet to an air flow outlet provided thereto; wherein said plural blood flow conduits and said plural airflow conduits at least partially comprise gas-permeable membrane material, and the conduits are arranged relative to each other such as to enable transfer of carbon dioxide from said blood flow to said air flow and transfer of oxygen from the air flow to the blood flow through said membrane material; and wherein said apparatus additionally comprises an adjuster that enables independent adjustment of the concentration of the carbon dioxide and oxygen in the blood flow; wherein the adjuster comprises a multi-way selector valve configured to select the relative flow pattern of the blood flow and the airflow; wherein a blood flow inlet multi-way valve enables separation of the blood flow into plural separate blood flows for directing to plural separate blood flow inlets of the plural blood flow conduits.
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62. A mixed-flow mass exchange apparatus for use in mass exchange comprising;
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(a) plural blood flow conduits for defining a blood flow from a blood flow inlet to a blood flow outlet provided thereto; and (b) plural air flow conduits for defining an air flow from an air flow inlet to an air flow outlet provided thereto; wherein said plural blood flow conduits and said plural airflow conduits at least partially comprise gas-permeable membrane material, and the conduits are arranged relative to each other such as to enable transfer of carbon dioxide from said blood flow to said air flow and transfer of oxygen from the air flow to the blood flow through said membrane material; and wherein said apparatus additionally comprises an adjuster that enables independent adjustment of the concentration of the carbon dioxide and oxygen in the blood flow; wherein the adjuster comprises a multi-way selector valve configured to select the relative flow pattern of the blood flow and the airflow; wherein a blood outlet multi-way valve enables separation of the blood flow into plural separate blood flows for directing from plural separate blood flow outlets of the plural blood flow conduits.
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Specification