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Biphasic calcium phosphate cement for drug delivery

  • US 8,529,933 B2
  • Filed: 07/26/2010
  • Issued: 09/10/2013
  • Est. Priority Date: 07/27/2009
  • Status: Active Grant
First Claim
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1. A settable biphasic composition in the form of a flowable paste, comprising:

  • a plurality of individual calcium phosphate particles wherein the calcium phosphate particles have a portion of the phosphate substituted with silicon;

    a liquid capable of supporting calcium phosphate precipitation;

    a bioabsorbable polymer at a concentration that enable tissue ingrowth into the composition upon polymer absorption; and

    sodium phosphate or potassium phosphate.

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