Method for analyzing function of the brain and other complex systems
First Claim
Patent Images
1. A computer-implemented method executed in an electronic data processing system having a computer program stored on computer readable media, the computer program for analyzing complex signals, the computer-implemented method comprising:
- obtaining, at the electronic data processing system, a first electronic signal representative of a first recorded brain signal of a living subject, the first electronic signal having a plurality of brain signal features, the first recorded brain signal having been recorded during a null condition when the living subject is not performing a task or receiving stimuli and is not in the midst of an epileptic event;
calculating, by the electronic data processing system and using the first electronic signal, a brain signal features baseline comprising a statistical distribution description for each brain signal feature, the brain signal features baseline modeling, for the null condition, a likelihood of fluctuation of each brain signal from a baseline value in the null condition;
obtaining, at the electronic data processing system, a second electronic signal representative of a second recorded brain signal of the living subject, the second electronic signal having a plurality of brain signal features, the second recorded brain signal having been recorded during a non-null condition of the living subject having been asked to perform a task or in the process of performing a task or the living subject receiving a form of stimuli; and
comparing, by the electronic data processing system, the brain signal features of the second recorded brain signal with the brain signal features baseline to detect statistical deviations representative of an event comprising an occurrence of functional activity of the living subject, the functional activity associated with the performance of the task or the reception of stimuli.
4 Assignments
0 Petitions
Accused Products
Abstract
A method and system are provided for analyzing electromagnetic brain signals such as EEG and ECoG signals in a subject in real time and which avoids the need for time-intensive retrospective analysis of brain activity in the subject. This can be applied to all complex systems with multiple fluctuating signals to identify and predict significant events.
23 Citations
16 Claims
-
1. A computer-implemented method executed in an electronic data processing system having a computer program stored on computer readable media, the computer program for analyzing complex signals, the computer-implemented method comprising:
-
obtaining, at the electronic data processing system, a first electronic signal representative of a first recorded brain signal of a living subject, the first electronic signal having a plurality of brain signal features, the first recorded brain signal having been recorded during a null condition when the living subject is not performing a task or receiving stimuli and is not in the midst of an epileptic event; calculating, by the electronic data processing system and using the first electronic signal, a brain signal features baseline comprising a statistical distribution description for each brain signal feature, the brain signal features baseline modeling, for the null condition, a likelihood of fluctuation of each brain signal from a baseline value in the null condition; obtaining, at the electronic data processing system, a second electronic signal representative of a second recorded brain signal of the living subject, the second electronic signal having a plurality of brain signal features, the second recorded brain signal having been recorded during a non-null condition of the living subject having been asked to perform a task or in the process of performing a task or the living subject receiving a form of stimuli; and comparing, by the electronic data processing system, the brain signal features of the second recorded brain signal with the brain signal features baseline to detect statistical deviations representative of an event comprising an occurrence of functional activity of the living subject, the functional activity associated with the performance of the task or the reception of stimuli. - View Dependent Claims (2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13)
-
-
14. A brain computer interface system comprising:
-
a plurality of brain electrodes for obtaining electromagnetic (EM) signals from the brain of a living subject; an electronic data processing system configured to gather, store and process EM signals obtained from the plurality of brain electrodes, the electronic data processing system comprising an executable computer program that when executed by a processing unit performs the following functions; collect a first EM brain signal from the living subject under a null condition when the living subject is not performing a task or receiving stimuli and is not in the midst of an epileptic event; calculate, using the first EM brain signal, a brain signal features baseline comprising a statistical distribution description for each brain signal feature of the first EM brain signal, the brain signal features baseline modeling, for the null condition, a likelihood of fluctuation of each brain signal from a baseline value in the null condition; collect a second EM brain signal from the living subject during a non-null condition of the living subject having been asked to perform a task or in the process of performing a task or the living subject receiving a form of stimuli; compare brain signal features of the second EM brain signal with the brain signal features baseline to detect statistical deviations representative of an event comprising an occurrence of functional activity associated with the performance of the task or the reception of stimuli. - View Dependent Claims (15, 16)
-
Specification
-
- Resources
Litigation Campaign Assessment
Thank you for your request. You will receive a custom alert email when the Litigation Campaign Assessment is available.
×
-
Current AssigneeHealth Research Incorporated, Washington University In St Louis
-
Original AssigneeWashington University In St Louis
-
InventorsSchalk, Gerwin, Leuthardt, Eric, Wolpaw, Jonathan, Brunner, Peter
-
Primary Examiner(s)Kahelin, Michael
-
Assistant Examiner(s)TOTH, KAREN E
-
Application NumberUS12/304,953Publication NumberTime in Patent Office2,281 DaysField of Search600544-545US Class Current600/544CPC Class CodesA61B 5/055 involving electronic [EMR] ...A61B 5/16 Devices for psychotechnics ...A61B 5/369 Electroencephalography [EEG...A61B 5/374 Detecting the frequency dis...A61B 5/398 Electrooculography [EOG], e...A61B 5/4094 Diagnosing or monitoring se...G16H 30/20 for handling medical images...
