Device for at least one of injection or aspiration

• US 8,535,268 B2
• Filed: 12/22/2010
• Issued: 09/17/2013
• Est. Priority Date: 12/22/2010
• Status: Active Grant

• Current Assignee: Alcon Incorporated
• Original Assignee: Alcon Research Limited (Nestle SA)
• Inventors: Auld, Jack Robert, McDonell, Brian William, Wheatley, Barry Lynn
• Primary Examiner(s): DeSanto, Matthew F
• Application Number:
  US12/976,038
• Publication Number:
  US 20120165734A1
• Time in Patent Office: 1,000 Days
• Field of Search: 604/118, 604131-155, 604/224, 604/181, 604/187, 604/218, 128/DIG.1, 128/DIG.7, 128/DIG.12
• US Class Current: 604/151
• CPC Class Codes: A61F 9/007 Methods or devices for eye surgery
• CPC Class Codes: A61M 2205/0294 Piezoelectric materials
• CPC Class Codes: A61M 2209/01 Remote controllers for specific apparatus
• CPC Class Codes: A61M 2210/0612 Eyes
• CPC Class Codes: A61M 5/1452 pressurised by means of pistons
• CPC Class Codes: A61M 5/14546 Front-loading type injectors
• CPC Class Codes: A61M 5/14566 with a replaceable reservoir for receiving a piston rod of the pump
• CPC Class Codes: A61M 5/16877 Adjusting flow; Devices for setting a flow rate
• CPC Class Codes: A61M 5/20 Automatic syringes, e.g. with automatically actuated piston rod, with automatic needle injection, filling automatically A61M5/142 , A61M5/46 take precedence; hypodermic projectiles F42B12/54
• CPC Class Codes: A61M 5/2053 Media being expelled from injector by pressurised fluid or vacuum for infusion A61M5/145, A61M5/155
• CPC Class Codes: A61M 5/31515 Connection of piston with piston rod
• CPC Class Codes: A61M 5/31583 based on rotational translation, i.e. movement of piston rod is caused by relative rotation between the user activated actuator and the piston rod

Abstract

Devices, systems, and associated methods that facilitate the injection and/or aspiration of precisely controlled volumes of fluids at precisely controlled rates are provided. In some implementations, an apparatus may include a syringe and a lead screw connected to a plunger of the syringe. A ratchet gear may be connected to the lead screw. A mechanism may also be included to oscillate a frame in a direction perpendicular to a longitudinal axis of the lead screw such that one or more pawls of the frame engage the teeth of the ratchet gear in a manner that results in rotation of the ratchet gear in a single direction for controlled linear displacement of the plunger.

Claims

1. A system, comprising:

an elongate body defining a cavity adapted to contain a material, the elongate body comprising a first opening in communication with the cavity;

a structure movable within the cavity, the structure adapted to be displaced within the cavity to expel an amount of the material from the cavity through the first opening;

a lead screw comprising;

a first portion coupled to the structure;

a second portion; and

a longitudinal axis;

a ratchet gear comprising a plurality of teeth, the ratchet gear coupled to the lead screw, the lead screw being rotatable with the ratchet gear;

a frame member comprising;

a first pawl; and

a second pawl, the first pawl and the second pawl adapted to engage teeth of the ratchet gear; and

an actuator, the actuator operable to oscillate the frame member perpendicular to the longitudinal axis of the lead screw such that the first pawl and the second pawl engage the teeth of the ratchet gear in a manner so as to rotate the ratchet gear in a single direction,

wherein at least a portion of the lead screw defines a channel extending parallel to the longitudinal axis, wherein the ratchet gear further comprises a protrusion, and wherein the protrusion of the ratchet gear is received into the channel.

2. The system of claim 1 further comprising a control system operable to control actuation of the actuator, wherein the actuator is in communication with the control system.

3. The system of claim 2, wherein the control system comprises a user-actuated controller, the controller operable to selectively activate the actuator.

4. The system of claim 3, wherein the control system further comprises an interactive control panel, the interactive control panel operable to receive from a user one or more parameters associated with dispensing the material from the cavity.

5. The system of claim 4, wherein the one or more parameters comprises at least one of a dosage volume, a maximum total dosage volume, or a flow rate.

6. The system of claim 5, wherein the control system is operable to correlate the one or more parameters to at least one of a number of oscillations of the actuator or a rate of oscillation of the actuator.

7. The system of claim 3, wherein the user-actuated controller is a foot pedal.

8. The system of claim 1 further comprising an advancement component selectively engagable with the lead screw.

9. The system of claim 8, wherein engagement of the advancement component with the lead screw facilitates translation of the structure within the cavity relative to the elongate body when the lead screw is rotated.

10. The system of claim 9, wherein disengagement of the advancement component from the lead screw allows manual translation of the lead screw relative to the elongate body without rotation of the lead screw.

11. The system of claim 8, wherein the lead screw comprises a threaded portion, wherein the advancement component comprises a threaded portion, and wherein the threaded portion of the lead screw and the threaded portion of the advancement component cooperate to translate a rotation of the lead screw into a linear movement of the lead screw along the longitudinal axis.

12. The system of claim 1, wherein the elongate body is a syringe.

13. The system of claim 12, wherein the structure movable within the cavity is a plunger.

14. The system of claim 12, wherein the first opening of the elongate body is defined by a needle.

15. The system of claim 1, wherein the actuator is a pneumatic actuator.

16. The system of claim 15, wherein the pneumatic actuator is a double acting piston.

17. The system of claim 1, wherein the first portion of the lead screw is movably coupled to the structure movable within the cavity.

18. The system of claim 1, wherein the lead screw is coupled to the ratchet gear such that the lead screw is slideable along the longitudinal axis relative to the lead screw.

19. The system of claim 1, wherein the first pawl is positioned on a first side of the ratchet gear and the second pawl is positioned on a second side of the ratchet gear substantially opposite the first pawl.

20. The system of claim 1, wherein the actuator is a hydraulic actuator.

21. The system of claim 1, wherein the actuator is an electric actuator.

22. The system of claim 1, wherein the actuator is a solenoid.

23. The system of claim 1, wherein the frame member further comprises:

a first flexible member coupled to the first pawl; and

a second flexible member coupled to the second pawl.

24. The system of claim 1, wherein the frame member further comprises:

a first end surface; and

a second end surface opposite the first ends surface;

wherein the housing comprises;

a bore, the frame member disposed in the bore; and

a first passage adjacent the first end surface of the frame member, and

wherein the actuator comprises;

the first end surface of the frame member; and

the first passage adjacent the first side of the frame member.

25. An apparatus comprising:

a syringe body defining a cavity;

a plunger disposed within the cavity, the plunger movable along a length of the syringe body within the cavity to dispense material from the cavity;

a lead screw coupled to the plunger;

a ratchet gear comprising a plurality of teeth, the ratchet gear coupled to the lead screw such that rotation of the ratchet gear causes rotation of the lead screw;

a structure having at least one pawl configured to engage the teeth of the ratchet gear;

a mechanism operable to oscillate the structure in a direction perpendicular to a longitudinal axis of the lead screw such that oscillation of the structure perpendicular to the longitudinal axis of the lead screw causes the at least one pawl of the structure to engage the teeth of the ratchet gear in a manner that results in rotation of the ratchet gear in a single direction; and

an advancement component selectively engagable with the lead screw,

wherein the lead screw comprises a threaded portion, wherein the advancement component comprises a threaded portion, and wherein the threaded portion of the lead screw and the threaded portion of the advancement component cooperate to translate a rotation of the lead screw into a linear movement of the lead screw along the longitudinal axis.

26. The apparatus of claim 25, wherein the at least one pawl comprises:

a first pawl; and

a second pawl, the first pawl being positioned on a first side of the ratchet gear and the second pawl being positioned on a second side of the ratchet gear substantially opposite the first pawl such that the first pawl and the second pawl alternatively engage the ratchet gear during oscillation of the structure.

27. The apparatus of claim 26, wherein the mechanism is selected from the group consisting of a pneumatic actuator, a hydraulic actuator, an electric actuator, a piezoelectric actuator, and a solenoid.

28. The apparatus of claim 27, wherein the mechanism is in communication with a control system that controls actuation of the mechanism, the control system comprising:

a user-actuated controller for selectively activating the mechanism; and

a control panel with a user interface that allows a user to set one or more parameters associated with dispensing the material from the cavity, the one or more parameters including one or more of dosage volume, a maximum total dosage volume, a dispense time, and a flow rate.