Prevention and treatment of amyloidogenic disease
First Claim
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1. A humanized antibody that specifically binds an epitope contained within positions 13-28 of Aβ
- , wherein the antibody is a humanized version of monoclonal antibody 266 (ATCC accession number PTA-6123).
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Abstract
The invention provides compositions and methods for treatment of amyloidogenic diseases. Such methods entail administering an agent that induces a beneficial immune response against an amyloid deposit in the patient. The methods are particularly useful for prophylactic and therapeutic treatment of Alzheimer'"'"'s disease. In such methods, a suitable agent is Aβ peptide, active fragments thereof or an antibody thereto.
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11 Claims
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1. A humanized antibody that specifically binds an epitope contained within positions 13-28 of Aβ
- , wherein the antibody is a humanized version of monoclonal antibody 266 (ATCC accession number PTA-6123).
- View Dependent Claims (2, 3, 4, 5, 6, 7, 8, 9, 10, 11)
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