Perflurochemical treatment process and apparatus
First Claim
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1. A process for treating a subject living organism, the process comprising:
- (a) confining at least a portion of the organism in a closed environment;
(b) providing a circulating perfluorochemical fluid in the closed environment;
(c) dissolving a selected gaseous material in the perfluorochemical fluid to provide perfluorochemical fluid containing the dissolved selected material;
(d) providing a pressure differing from atmospheric pressure in the closed environment;
(e) immersing the at least a portion of the organism in the perfluorochemical fluid containing the selected gaseous material; and
(f) alternately pressurizing the closed environment to a first pressure and a second pressure, in a cycled manner, the pressure cycling employing cardiac gating, such that the variation of pressure is synchronized with cardiac rhythms.
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Abstract
A subject is confined in a closed environment at an elevated pressure through which perfluorochemical fluid containing dissolved oxygen is circulated to treat disease or injury.
27 Citations
17 Claims
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1. A process for treating a subject living organism, the process comprising:
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(a) confining at least a portion of the organism in a closed environment; (b) providing a circulating perfluorochemical fluid in the closed environment; (c) dissolving a selected gaseous material in the perfluorochemical fluid to provide perfluorochemical fluid containing the dissolved selected material; (d) providing a pressure differing from atmospheric pressure in the closed environment; (e) immersing the at least a portion of the organism in the perfluorochemical fluid containing the selected gaseous material; and (f) alternately pressurizing the closed environment to a first pressure and a second pressure, in a cycled manner, the pressure cycling employing cardiac gating, such that the variation of pressure is synchronized with cardiac rhythms. - View Dependent Claims (2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 16, 17)
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Specification