Systems, methods, and devices having stretchable integrated circuitry for sensing and delivering therapy
First Claim
1. An apparatus for detecting and measuring aspects of a tissue of a subject'"'"'s body, comprising:
- a. a stretchable substrate;
b. stretchable circuitry disposed on said stretchable substrate, said stretchable circuitry comprising;
(i) a first array of sensing devices comprising contact sensors to generate data indicating that one or more sensors of said first array of sensing devices is in contact with said tissue and to generate data indicative of an area of said contact;
(ii) a second array of sensing devices to detect data indicative of a parameter of said tissue; and
(iii) a plurality of stretchable interconnects to electrically interconnect at least some of the sensing devices of the first array of sensing devices or at least some of the sensing devices of the second array of sensing devices; and
c. a processing facility in electronic communication with said stretchable circuitry, wherein the processing facility receives data indicative of said area of said contact and activates one or more sensing devices of said second array of sensing devices that correspond to said area of said contact.
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Accused Products
Abstract
System, devices and methods are presented that integrate stretchable or flexible circuitry, including arrays of active devices for enhanced sensing, diagnostic, and therapeutic capabilities. The invention enables conformal sensing contact with tissues of interest, such as the inner wall of a lumen, a the brain, or the surface of the heart. Such direct, conformal contact increases accuracy of measurement and delivery of therapy. Further, the invention enables the incorporation of both sensing and therapeutic devices on the same substrate allowing for faster treatment of diseased tissue and fewer devices to perform the same procedure.
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Citations
37 Claims
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1. An apparatus for detecting and measuring aspects of a tissue of a subject'"'"'s body, comprising:
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a. a stretchable substrate; b. stretchable circuitry disposed on said stretchable substrate, said stretchable circuitry comprising; (i) a first array of sensing devices comprising contact sensors to generate data indicating that one or more sensors of said first array of sensing devices is in contact with said tissue and to generate data indicative of an area of said contact; (ii) a second array of sensing devices to detect data indicative of a parameter of said tissue; and (iii) a plurality of stretchable interconnects to electrically interconnect at least some of the sensing devices of the first array of sensing devices or at least some of the sensing devices of the second array of sensing devices; and c. a processing facility in electronic communication with said stretchable circuitry, wherein the processing facility receives data indicative of said area of said contact and activates one or more sensing devices of said second array of sensing devices that correspond to said area of said contact. - View Dependent Claims (2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 16, 17, 18, 19, 20, 21, 22, 23, 24, 25, 26, 27, 28, 29, 30, 31, 32, 33)
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34. An apparatus for delivery of a therapeutic agent to tissue in a subject'"'"'s body, the apparatus comprising:
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a stretchable substrate; a stretchable circuit positioned at least in part on said stretchable substrate, the stretchable circuitry comprising; a first plurality of electrodes coupled to the stretchable substrate, the first plurality of electrodes configured to deliver the therapeutic agent; a second plurality of contact sensors coupled to the stretchable substrate, the second plurality of contact sensors configured to generate data indicative of contact of a portion of the apparatus with the tissue, and a plurality of stretchable interconnects to electrically interconnect at least some of the electrodes of the first plurality of electrodes or at least some of the contact sensors of the second plurality of contact sensors; and at least one processing device coupled to the first plurality of electrodes configured to deliver the therapeutic agent and the second plurality of contact sensors, the processing device configured to activate one or more electrode in the first plurality of electrodes in response to receipt of a signal from one or more contact sensors of the plurality of contact sensors indicative of contact of the portion of the apparatus with the tissue. - View Dependent Claims (35, 36, 37)
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Specification