Evaluating therapeutic stimulation electrode configurations based on physiological responses
First Claim
1. A medical device comprising:
- a means for delivering stimulation therapy to a patient using a plurality of electrode configurations;
a means for determining a response of a target tissue for each of the plurality of electrode configurations;
an accelerometer that outputs a signal corresponding to a response of non-target tissue for each of the plurality of electrode configurations;
a means for evaluating the response of the target tissue and the signal corresponding to the response of the non-target tissue for each of the plurality of electrode configurations to determine the relative suitability of the electrode configurations for delivering stimulation therapy to target tissue of the patient; and
a means for presenting an indication of the relative suitability of the of the electrode configurations to a use;
at least one implantable medical lead, wherein the at least one implantable medical lead includes a plurality of electrodes providing the plurality of electrode configurations; and
wherein the at least one implantable medical lead comprises a cardiac pacing lead, wherein the target tissue comprises tissue of the left ventricle of the patient and the non-target tissue comprises tissue of the phrenic nerve of the patient.
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Abstract
A medical system comprises a plurality of electrodes; at least one sensor configured to output at least one signal based on at least one physiological parameter of a patient; and a processor. The processor is configured to control delivery of stimulation to the patient using a plurality of electrode configurations. Each of the electrode configurations comprises at least one of the plurality of electrodes. For each of the electrode configurations, the processor is configured to determine a first response of target tissue to the stimulation based on the signals, and a second response of non-target tissue to the stimulation based on the signals. The processor is also configured to select at least one of the electrode configurations for delivery of stimulation to the patient based on the first and second responses for the electrode configurations. As examples, the target tissue may be a left ventricle or vagus nerve.
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Citations
16 Claims
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1. A medical device comprising:
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a means for delivering stimulation therapy to a patient using a plurality of electrode configurations; a means for determining a response of a target tissue for each of the plurality of electrode configurations; an accelerometer that outputs a signal corresponding to a response of non-target tissue for each of the plurality of electrode configurations; a means for evaluating the response of the target tissue and the signal corresponding to the response of the non-target tissue for each of the plurality of electrode configurations to determine the relative suitability of the electrode configurations for delivering stimulation therapy to target tissue of the patient; and a means for presenting an indication of the relative suitability of the of the electrode configurations to a use; at least one implantable medical lead, wherein the at least one implantable medical lead includes a plurality of electrodes providing the plurality of electrode configurations; and wherein the at least one implantable medical lead comprises a cardiac pacing lead, wherein the target tissue comprises tissue of the left ventricle of the patient and the non-target tissue comprises tissue of the phrenic nerve of the patient. - View Dependent Claims (2, 3, 4, 5, 6, 7)
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8. A medical device comprising:
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a means for delivering stimulation therapy to a patient using a plurality of electrode configurations; a means for determining a response of a target tissue for each of the plurality of electrode configurations; an accelerometer that outputs a signal corresponding to a response of non-target tissue for each of the plurality of electrode configurations; a means for evaluating the response of the target tissue and the signal corresponding to the response of the non-target tissue for each of the plurality of electrode configurations to determine the relative suitability of the electrode configurations for delivering stimulation therapy to target tissue of the patient; and a means for presenting an indication of the relative suitability of the of the electrode configurations to a use; at least one implantable medical lead, wherein the at least one implantable medical lead includes a plurality of electrodes providing the plurality of electrode configurations; and wherein the target tissue comprises tissue of the vagus nerve of the patient and the non-target tissue comprises muscle tissue of the patient adjacent to the vagus nerve.
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9. A medical system comprising:
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one or more implantable medical leads, the implantable medical leads including a plurality of electrodes; one or more sensors configured to output one or more signals based on at least one physiological parameter of a patient; and a processor configured to; control delivery of stimulation to the patient using a plurality of electrode configurations, wherein each of the electrode configurations comprises at least one of the plurality of electrodes, for each of the electrode configurations, determine a first response of the left ventricle of the patient to the stimulation based on the signals and a second response of tissue of the phrenic nerve of the patient to the stimulation based on the signals, wherein the processor determines the second response of tissue of the phrenic nerve using an input from an accelerometer, and present indications of the first response of the left ventricle of the patient to the stimulation and the second response of tissue of the phrenic nerve of the patient to a user via a user interface. - View Dependent Claims (10, 11, 12)
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13. A medical system comprising:
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one or more implantable medical leads, the implantable medical leads including a plurality of electrodes; one or more sensors configured to output one or more signals based on at least one physiological parameter of a patient; and a processor configured to; control delivery of stimulation to the patient using a plurality of electrode configurations, wherein each of the electrode configurations comprises at least one of the plurality of electrodes, for each of the electrode configurations, determine a first response of the vagus nerve of the patient to the stimulation based on the signals, and a second response of muscle tissue of the patient adjacent to the vagus nerve to the stimulation based on the signals, wherein the processor determines the second response of the muscle tissue of the patient adjacent to the vagus nerve using an input from an accelerometer, and present indications of the first response of the vagus nerve of the patient to the stimulation and the second response of the muscle tissue of the patient adjacent to the vagus nerve to a user via a user interface. - View Dependent Claims (14, 15, 16)
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Specification