Gel phantoms for testing cavitational ultrasound (histotripsy) transducers
First Claim
1. A cavitational damage indicator phantom, comprising:
- a container;
a gel disposed in the container; and
an indicator disposed in the container, the indicator configured to change visibly during application of cavitational ultrasound energy to the indicator.
2 Assignments
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Accused Products
Abstract
A cavitational ultrasound (e.g., Histotripsy) gel phantom and cavitational ultrasound testing system are provided that may include any of a number of features. One feature of the phantom and system is that it can allow for instant visual feedback on the efficacy and dosage of a Histotripsy transducer. The changes in the gel phantom can be visualized with the naked eye without having to wait for histology. The changes in the gel phantom can also be visualized with a camera, with ultrasound imaging, or with microscopy. In various embodiments, the phantom includes indicators such as carbon particles, dye-encapsulated beads, and red blood cells. Methods associated with use of the cavitational ultrasound gel phantom and testing system are also covered.
239 Citations
41 Claims
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1. A cavitational damage indicator phantom, comprising:
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a container; a gel disposed in the container; and an indicator disposed in the container, the indicator configured to change visibly during application of cavitational ultrasound energy to the indicator. - View Dependent Claims (2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 16, 17, 18)
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19. A cavitational damage testing system, comprising:
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a tank filled with an acoustic medium; and a cavitational ultrasound phantom disposed in the tank, the cavitational ultrasound phantom comprising a container, a gel disposed in the container, and an indicator disposed in the container, the indicator configured to change visibly under application of cavitational ultrasound energy to the indicator. - View Dependent Claims (20, 21, 22, 23, 24, 25, 26, 27, 28, 29, 30, 31, 32, 33)
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34. A method of testing a Histotripsy transducer, comprising:
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applying Histotripsy energy to a Histotripsy phantom; and observing a visual change in the Histotripsy phantom. - View Dependent Claims (35, 36, 37, 38, 39, 40, 41)
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Specification