Microfluidic device and method of loading sample into the microfluidic device
First Claim
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1. A microfluidic device comprising:
- a sample chamber in which a sample is accommodated, wherein the sample chamber comprises;
an introduction portion comprising a loading hole through which the sample is loaded;
an accommodation portion comprising a discharge hole; and
a neck portion which forms a boundary between the introduction portion and the accommodation portion and provides a capillary pressure for controlling flow of the sample between the introduction portion and the accommodation portion,wherein a bottom surface of the introduction portion is inclined upward to the neck portion from the loading hole to prevent flowing backward of the sample, andwherein a distance from a center of the microfluidic device to a sidewall of the sample chamber gradually increases from the neck portion to the discharge hole.
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Abstract
Provided is a microfluidic device. The microfluidic device includes a sample chamber in which a sample is accommodated. The sample chamber includes: an introduction portion including a loading hole through which the sample is loaded; an accommodation portion including a discharge hole; and a neck portion forming a boundary between the introduction portion and the accommodation portion. The neck portion provides a capillary pressure for controlling flow of the sample between the introduction portion and the accommodation portion.
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Citations
20 Claims
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1. A microfluidic device comprising:
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a sample chamber in which a sample is accommodated, wherein the sample chamber comprises; an introduction portion comprising a loading hole through which the sample is loaded; an accommodation portion comprising a discharge hole; and a neck portion which forms a boundary between the introduction portion and the accommodation portion and provides a capillary pressure for controlling flow of the sample between the introduction portion and the accommodation portion, wherein a bottom surface of the introduction portion is inclined upward to the neck portion from the loading hole to prevent flowing backward of the sample, and wherein a distance from a center of the microfluidic device to a sidewall of the sample chamber gradually increases from the neck portion to the discharge hole. - View Dependent Claims (2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12)
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13. A microfluidic device comprising:
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a sample chamber in which a sample is accommodated, wherein the sample chamber comprises an introduction portion comprising a loading hole through which the sample is loaded, and a neck portion which provides a capillary pressure for controlling flow of the sample between the introduction portion and the accommodation portion, wherein a bottom surface of the introduction portion is inclined upward to the neck portion from the loading hole to prevent flowing backward of the sample, and wherein a distance from a center of the microfluidic device to a sidewall of the sample chamber gradually increases from the neck portion to the discharge hole; and an analysis unit which receives and analyzes the sample from the sample chamber, wherein the analysis unit comprises; a sample measuring portion which measures the sample; and a sample detection chamber which is connected to the sample measuring portion and in which a portion of the sample exceeding a capacity of the sample measuring portion is accommodated; and a surplus sample chamber which is connected to the sample detection chamber and in which a portion of the sample exceeding a capacity of the sample detection chamber is accommodated. - View Dependent Claims (14, 15, 16, 17, 18)
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19. A microfluidic device comprising:
- a sample chamber in which a sample is accommodated; and
an analysis unit which receives the sample from the sample chamber and comprises at least one reaction chamber for analyzing the sample, wherein the sample chamber comprises;
a loading hole through which the sample is loaded;
a discharge hole which is connected to the analysis unit; and
a neck portion comprising a capillary valve which is disposed between the loading hole and the discharge hole and passes the sample only when a predetermined pressure is applied to the sample, wherein the capillary valve comprises a protrusion formed by first and second inclined portions of a bottom surface of the sample chamber, and wherein a distance from the center of the microfluidic device to a sidewall of the sample chamber gradually increases from the neck portion to the discharge hole. - View Dependent Claims (20)
- a sample chamber in which a sample is accommodated; and
Specification