Physiological and behavioral sensors and methods

• US 8,540,651 B2
• Filed: 09/16/2010
• Issued: 09/24/2013
• Est. Priority Date: 09/16/2010
• Status: Active Grant

• Current Assignee: Charles Stark Draper Laboratory Incorporated
• Original Assignee: Charles Stark Draper Laboratory Incorporated
• Inventors: Pfeffer, Lawrence E., Wendelken, Suzanne M., Fulford, Adam T., Webb, Andrea K.
• Primary Examiner(s): HINDENBURG, MAX F
• Application Number:
  US12/883,451
• Publication Number:
  US 20120071792A1
• Time in Patent Office: 1,104 Days
• Field of Search: 600/587, 600/595, 600/592
• US Class Current: 600/595
• CPC Class Codes: A61B 2562/0252 Load cells
• CPC Class Codes: A61B 2562/046 in a matrix array
• CPC Class Codes: A61B 5/11 Measuring movement of the entire body or parts thereof, e.g. head or hand tremor, mobility of a limb for measuring pulse A61B5/02 ;A61B5/1038 takes precedence; motion detection to correct for motion artifacts in physiological signals A61B5/721
• CPC Class Codes: A61B 5/1102 Ballistocardiography
• CPC Class Codes: A61B 5/164 Lie detection
• CPC Class Codes: A61B 5/165 Evaluating the state of mind, e.g. depression, anxiety
• CPC Class Codes: A61B 5/4023 Evaluating sense of balance
• CPC Class Codes: A61B 5/6891 Furniture
• CPC Class Codes: A61B 5/70 Means for positioning the patient in relation to the detecting, measuring or recording means
• CPC Class Codes: G01G 19/50 having additional measuring devices, e.g. for height

Abstract

In various embodiments, a physiological or behavioral signal is derived from a vertical force resulting from the entire weight of a subject. A system for measuring physiological and behavioral signals in a human subject may include a measurement platform for bearing the subject, at least one force sensor for measuring vertical force imparted by an entire weight of the subject, and a signal processor for deriving at least one physiological or behavioral signal, such as a ballistocardiogram, from the measured force. The force sensor(s) may support the measurement platform and be disposed between the measurement platform and a support surface.

Claims

1. A system for measuring physiological and behavioral signals in a human subject, the system comprising:

a measurement platform for bearing the subject;

at least one of a substantially stationary support or a chair disposed entirely on the platform such that an entire weight of the support or chair is supported by the platform;

at least one force sensor for measuring vertical force imparted by an entire weight of the subject, the at least one force sensor supporting the measurement platform and disposed between the measurement platform and a support surface; and

a signal processor for deriving at least one physiological or behavioral signal, including a ballistocardiogram, from the measured force.

2. The system of claim 1, wherein the at least one force sensor measures only substantially vertical force.

3. The system of claim 1, further comprising a bearing disposed between each said at least one force sensor and the platform, the bearing substantially transmitting vertical force but not torque from the platform to the force sensor.

4. The system of claim 1, wherein the at least one force sensor comprises at least three non-collinear force sensors disposed proximate a periphery of the platform.

5. The system of claim 1, wherein the signal processor comprises at least one calibration module for calibrating the vertical force, thereby substantially eliminating at least one of bias, slope error, hysteresis, or non-linearity from the vertical force.

6. The system of claim 1, wherein the signal processor comprises at least one taring module for subtracting from the vertical force a weight contribution from the platform.

7. The system of claim 1, wherein (i) the at least one force sensor comprises a plurality of force sensors, and (ii) the signal processor comprises a summation module for summing vertical force measured by each of the force sensors.

8. The system of claim 1, wherein the signal processor comprises a high-pass filtering module for removing a steady-state component from a total vertical force measured by the at least one force sensor.

9. The system of claim 8, wherein the high-pass filtering module removes from the total vertical force a spectral component having a frequency below a cardiac frequency of interest.

10. The system of claim 8, wherein the high-pass filtering module comprises a Bessel filter.

11. The system of claim 1, wherein the signal processor comprises a low-pass filtering module for removing, from a total vertical force measured by the at least one force sensor, a spectral component having a frequency above a cardiac frequency of interest.

12. The system of claim 1, wherein the signal processor comprises a centroid-calculating module for determining a center of gravity of the subject based on the measured force.

13. The system of claim 12, wherein at least one derived physiological or behavioral signal comprises at least one of jitter or hypervigilance.

14. A method for measuring physiological and behavioral signals, the method comprising:

measuring a vertical force imparted by an entire weight of a human subject having a substantially vertical thorax and disposed upon a measurement platform, the vertical force measured by at least one force sensor that supports the measurement platform and is disposed between the measurement platform and a support surface, at least one of a substantially stationary support or a chair being disposed entirely on the platform such that an entire weight of the support or chair is supported by the platform; and

extracting at least one physiological or behavioral signal, including a ballistocardiogram, from the measured vertical force.

15. The method of claim 14, wherein the at least one physiological or behavioral signal is extracted without sensors attached to the subject.

16. The method of claim 14, further comprising calibrating the measured vertical force to substantially eliminate at least one of bias, slope error, hysteresis, or non-linearity therefrom.

17. The method of claim 14, further comprising subtracting from the vertical force a weight contribution of the platform.

18. The method of claim 14, wherein extracting the at least one physiological or behavioral signal comprises removing from the measured vertical force at least one spectral component having a frequency above or below a cardiac frequency of interest.

19. The method of claim 14, wherein extracting the at least one physiological or behavioral signal comprises removing from the measured vertical force a steady-state component corresponding to the entire weight of the subject.

20. The method of claim 14, wherein extracting the at least one physiological or behavioral signal comprises determining a center of gravity of the subject.

21. The method of claim 14, wherein at least one extracted physiological or behavioral signal comprises at least one of jitter or hypervigilance.

22. The method of claim 14, wherein the vertical force is measured by a plurality of force sensors disposed proximate a periphery of the platform.

23. The method of claim 14, further comprising at least one of interviewing the subject or subjecting the subject to a cognitive stimulus while measuring the vertical force.