Controlled detachment of intra-luminal medical device

• US 8,540,679 B2
• Filed: 02/02/2010
• Issued: 09/24/2013
• Est. Priority Date: 03/30/2004
• Status: Active Grant

• Current Assignee: Given Imaging Limited (Medtronic Plc)
• Original Assignee: Given Imaging Limited (Medtronic Plc)
• Inventors: Christopherson, Mark A., Dinsmoor, David A
• Primary Examiner(s): Sirmons, Kevin C
• Assistant Examiner(s): GILBERT, ANDREW M
• Application Number:
  US12/698,811
• Publication Number:
  US 20100217368A1
• Time in Patent Office: 1,330 Days
• Field of Search: 604174-178, 604/164.04, 600/350, 607/40
• US Class Current: 604/174
• CPC Class Codes: A61B 5/145 Measuring characteristics of blood in vivo, e.g. gas concentration, pH value; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid, cerebral tissuemeasuring of blood pressure or blood flow A61B5/02; non-radiation detecting or locating of foreign bodies in blood A61B5/06
• CPC Class Codes: A61B 5/14539 for measuring pH
• CPC Class Codes: A61B 5/6882 Anchoring means
• CPC Class Codes: A61N 1/36007 of urogenital or gastrointestinal organs, e.g. for incontinence control
• CPC Class Codes: A61N 1/372 Arrangements in connection with the implantation of stimulators

Abstract

An intra-luminal medical device includes a fixation mechanism to attach the medical device to tissue within a body lumen, and a detachment mechanism to permit selective detachment of the medical device from the tissue attachment site without the need for endoscopic or surgical intervention. An electromagnetic device may be provided to mechanically actuate the detachment mechanism. Alternatively, a fuse link may be electrically blown to detach the medical device. As a further alternative, a rapidly degradable bonding agent may be exposed to a degradation agent to detach the medical device from a bonding surface within the body lumen. The medical device may eliminate problems associated with uncertain and inconsistent detachment of intra-luminal medical devices.

Claims

1. A medical device comprising:

a device housing sized for introduction into and residence completely within a gastrointestinal tract;

a fixation mechanism to attach the device housing to a surface within the gastrointestinal tract;

a controlled detachment mechanism mechanically actuating the fixation mechanism to selectively detach the device housing from the surface of the gastrointestinal tract without endoscopic intervention, wherein the detachment mechanism comprises a fuse link; and

a controller responsive to a control signal, wherein the controller activates the controlled detachment mechanism to apply current across the fuse link, and wherein the medical device remains completely within the gastrointestinal tract until after the device is detached from the surface, and wherein after the device is detached from the surface the device passes through the gastrointestinal tract for excretion by the patient.

2. The medical device of claim 1, comprising a cavity including a vacuum port for application of vacuum pressure to draw tissue into the cavity.

3. The medical device of claim 1, wherein the fuse link comprises fuse material that is vaporized or melted when current is applied to the fuse link.

4. The medical device of claim 1, further comprising a power source to power the detachment mechanism.

5. The medical device of claim 4, wherein the power source includes a battery.

6. The medical device of claim 4, wherein the power source includes an inductive coupling circuit to generate power from an inductive element external to the gastrointestinal tract.

7. The medical device of claim 1, wherein the controller includes a telemetry circuit to receive the control signal as a telemetry signal from an external controller.

8. The medical device of claim 1, wherein the controller includes an inductive coupling circuit to sense the presence of an external inductive element as the control signal.

9. The medical device of claim 1, wherein the controller includes an inductive coupling circuit to generate power from an inductive element external to the gastrointestinal tract and thereby drive the detachment mechanism with the generated power.

10. The medical device of claim 1, wherein the device housing is sized for introduction into the esophagus.

11. The medical device of claim 1, wherein the device housing is sized for passage through the gastrointestinal tract.

12. The medical device of claim 1, further comprising a sensor, mounted to the device housing, to sense at least one condition within the gastrointestinal tract.

13. The medical device of claim 1, further comprising a sensor, mounted to the device housing, to sense at least one of pH, flow, temperature, and pressure within the gastrointestinal tract.

14. The medical device of claim 1, further comprising:

an electrical pulse generator, mounted within the device housing, to generate an electrical stimulation waveform;

one or more electrodes electrically coupled to the electrical pulse generator and mounted to the device housing to deliver the electrical stimulation waveform to the gastrointestinal tract.

15. A method for attaching and detaching a medical device within the gastrointestinal tract of a patient, the method comprising:

positioning the medical device at a target location within a gastrointestinal tract;

activating a fixation mechanism carried by the medical device to attach the medical device to a surface within the gastrointestinal tract; and

activating a controlled mechanically actuated detachment mechanism carried by the medical device to detach the medical device from the surface of the gastrointestinal tract without endoscopic intervention, wherein the detachment mechanism comprises a fuse link, and wherein the detachment mechanism is activated to apply current across the fuse link in response to receipt of a control signal from a controller external to the gastrointestinal tract, and wherein after the device is detached from the surface the device passes through the gastrointestinal tract for excretion by the patient.

16. The method of claim 15, comprising a cavity including a vacuum port for application of vacuum pressure to draw tissue into the cavity, and activating a fixation mechanism includes applying vacuum pressure to the vacuum port.

17. The method of claim 15, further comprising powering the detachment mechanism with a battery carried by the medical device.

18. The method of claim 15, further comprising powering the detachment mechanism with power generated by an inductive coupling circuit carried by the medical device in response to inductive energy generated by an inductive element external to the gastrointestinal tract.

19. The method of claim 15, further comprising activating the detachment mechanism in response to presence of an external magnetic source.

20. The method of claim 15, further comprising positioning the medical device within the esophagus of the patient.

21. The method of claim 15, further comprising sensing at least one of pH, flow, temperature, and pressure within the gastrointestinal tract with a sensor carried by the medical device.

22. The method of claim 15, further comprising:

generating an electrical stimulation waveform; and

delivering the electrical stimulation waveform to the tissue via one or more electrodes carried by the medical device.