Morphinan compounds
First Claim
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1. A method for the treatment of a subject suffering from or susceptible to a disease or condition selected from emotional lability;
- pseudobulbar affect;
chronic pain;
intractable pain;
neuropathic pain;
sexual dysfunction;
intractable coughing;
dermatitis; and
Rett syndrome (RTT), comprising administering to the subject a compound according to formula I;
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Abstract
This disclosure relates to novel morphinan compounds and their derivatives, pharmaceutically acceptable salts, solvates, and hydrates thereof. This disclosure also provides compositions comprising a compound of this disclosure and the use of such compositions in methods of treating diseases and conditions that are beneficially treated by administering a σ1 receptor agonist that also has NMDA antagonist activity.
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Citations
9 Claims
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1. A method for the treatment of a subject suffering from or susceptible to a disease or condition selected from emotional lability;
- pseudobulbar affect;
chronic pain;
intractable pain;
neuropathic pain;
sexual dysfunction;
intractable coughing;
dermatitis; and
Rett syndrome (RTT), comprising administering to the subject a compound according to formula I;
- View Dependent Claims (2, 3, 4, 5)
- pseudobulbar affect;
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6. Separate dosage forms of:
(i) a compound of formula I; - View Dependent Claims (7, 8, 9)
Specification