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Device for modulation of neuronal activity in the brain by means of sensory stimulation and detection of brain activity

  • US 8,543,219 B2
  • Filed: 07/05/2003
  • Issued: 09/24/2013
  • Est. Priority Date: 07/29/2002
  • Status: Expired due to Fees
First Claim
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1. A device for desynchronizing pathologically rhythmic brain activity, the device comprising:

  • a stimulator configured to generate a plurality of pulses at a plurality of excitation frequencies, respectively, to stimulate neuronal rhythmic activity in a patient'"'"'s brain;

    a sensor configured to measure the neuronal rhythmic activity in response to the plurality of pulses; and

    a control unit configured to determine at least one frequency of the plurality of excitation frequencies in which the sensor measures a maximum excitation of the neuronal rhythmic activity in response to the plurality of pulses;

    wherein the control unit is further configured to control the stimulator to generate an entraining periodic pulse sequence operating at the at least one frequency to entrain the phase dynamic of the neuronal rhythmic activity,wherein the stimulator is further configured to generate a desynchronization pulse following the entraining periodic pulse sequence to desynchronize the neuronal rhythmic activity, andwherein the plurality of pulses, the entraining pulse sequence and the desynchronization pulse are either visual or acoustic or tactile.

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