Device for modulation of neuronal activity in the brain by means of sensory stimulation and detection of brain activity
First Claim
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1. A device for desynchronizing pathologically rhythmic brain activity, the device comprising:
- a stimulator configured to generate a plurality of pulses at a plurality of excitation frequencies, respectively, to stimulate neuronal rhythmic activity in a patient'"'"'s brain;
a sensor configured to measure the neuronal rhythmic activity in response to the plurality of pulses; and
a control unit configured to determine at least one frequency of the plurality of excitation frequencies in which the sensor measures a maximum excitation of the neuronal rhythmic activity in response to the plurality of pulses;
wherein the control unit is further configured to control the stimulator to generate an entraining periodic pulse sequence operating at the at least one frequency to entrain the phase dynamic of the neuronal rhythmic activity,wherein the stimulator is further configured to generate a desynchronization pulse following the entraining periodic pulse sequence to desynchronize the neuronal rhythmic activity, andwherein the plurality of pulses, the entraining pulse sequence and the desynchronization pulse are either visual or acoustic or tactile.
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Abstract
The invention relates to a device for controlled modulation of physiological and pathological neuronal rhythmic activity in the brain by means of sensory stimulation, which is capable of diagnostically ascertaining functional disorders in the brain and of alleviating or eliminating the symptoms of a functional disruption. According to the invention, the device comprises a control unit (4), a stimulator (1) and at least one means for detecting brain activity, said means being connected to the control unit (1).
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Citations
32 Claims
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1. A device for desynchronizing pathologically rhythmic brain activity, the device comprising:
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a stimulator configured to generate a plurality of pulses at a plurality of excitation frequencies, respectively, to stimulate neuronal rhythmic activity in a patient'"'"'s brain; a sensor configured to measure the neuronal rhythmic activity in response to the plurality of pulses; and a control unit configured to determine at least one frequency of the plurality of excitation frequencies in which the sensor measures a maximum excitation of the neuronal rhythmic activity in response to the plurality of pulses; wherein the control unit is further configured to control the stimulator to generate an entraining periodic pulse sequence operating at the at least one frequency to entrain the phase dynamic of the neuronal rhythmic activity, wherein the stimulator is further configured to generate a desynchronization pulse following the entraining periodic pulse sequence to desynchronize the neuronal rhythmic activity, and wherein the plurality of pulses, the entraining pulse sequence and the desynchronization pulse are either visual or acoustic or tactile. - View Dependent Claims (2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 16, 17, 18, 19, 20, 21, 22, 23, 24, 25, 26, 27, 28, 29, 30, 31, 32)
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Specification