Devices, systems and methods for medicament delivery

• US 8,544,645 B2
• Filed: 05/04/2012
• Issued: 10/01/2013
• Est. Priority Date: 02/01/2005
• Status: Active Grant

• Current Assignee: Kaleo, Inc.
• Original Assignee: Intelliject Incorporated
• Inventors: Edwards, Eric Shawn, Edwards, Evan Thomas, Licata, Mark J., Williamson, T. Spencer
• Primary Examiner(s): SCHMIDT, EMILY LOUISE
• Application Number:
  US13/464,234
• Publication Number:
  US 20120280815A1
• Time in Patent Office: 515 Days
• Field of Search: 604/189, 206363-370
• US Class Current: 206/364
• CPC Class Codes: A61M 2005/2013 triggering of discharging means by contact of injector with patient body
• CPC Class Codes: A61M 2005/2026 Semi-automatic, e.g. user activated piston is assisted by additional source of energy
• CPC Class Codes: A61M 2005/206 With automatic needle insertion
• CPC Class Codes: A61M 2005/2073 preventing premature release, e.g. by making use of a safety lock
• CPC Class Codes: A61M 2005/3128 Incorporating one-way valves, e.g. pressure-relief or non-return valves
• CPC Class Codes: A61M 2039/1083 having a plurality of female connectors, e.g. Luer connectors
• CPC Class Codes: A61M 2039/1088 having a plurality of male connectors, e.g. Luer connectors
• CPC Class Codes: A61M 2205/13 with means for the detection of operative contact with patient, e.g. lip sensor
• CPC Class Codes: A61M 2205/14 Detection of the presence or absence of a tube, a connector or a container in an apparatus
• CPC Class Codes: A61M 2205/18 with alarm
• CPC Class Codes: A61M 2205/3576 with non implanted data transmission devices, e.g. using external transmitter or receiver
• CPC Class Codes: A61M 2205/50 with microprocessors or computers
• CPC Class Codes: A61M 2205/502 User interfaces, e.g. screens or keyboards
• CPC Class Codes: A61M 2205/581 by audible feedback
• CPC Class Codes: A61M 2205/582 by tactile feedback
• CPC Class Codes: A61M 2205/583 by visual feedback
• CPC Class Codes: A61M 2205/6018 providing set-up signals for the apparatus configuration
• CPC Class Codes: A61M 2205/6036 characterised by physical shape, e.g. array of activating switches
• CPC Class Codes: A61M 5/19 having more than one chamber , e.g. including a manifold coupling two parallelly aligned syringes through separate channels to a common discharge assembly surgical glue applicators A61B17/00491
• CPC Class Codes: A61M 5/2033 Spring-loaded one-shot injectors with or without automatic needle insertion multishot dosing syringes A61M5/31525, needle insertion only A61M5/3287
• CPC Class Codes: A61M 5/2046 : Media being expelled from injector by gas generation, e.g. explosive charge
• CPC Class Codes: A61M 5/2053 : Media being expelled from injector by pressurised fluid or vacuum for infusion A61M5/145, A61M5/155
• CPC Class Codes: A61M 5/2066 : comprising means for injection of two or more media, e.g. by mixing
• CPC Class Codes: A61M 5/24 : Ampoule syringes, i.e. syringes with needle for use in combination with replaceable ampoules or carpules, e.g. automatic ampoules or carpules A61J1/06
• CPC Class Codes: A61M 5/2448 : comprising means for injection of two or more media, e.g. by mixing
• CPC Class Codes: A61M 5/3129 : Syringe barrels A61M5/3205 and A61M5/50 take precedence
• CPC Class Codes: A61M 5/3204 : Needle cap remover, i.e. devices to dislodge protection cover from needle or needle hub, e.g. deshielding devices
• CPC Class Codes: A61M 5/326 : Fully automatic sleeve extension, i.e. in which triggering of the sleeve does not require a deliberate action by the user
• CPC Class Codes: A61M 5/3287 : Accessories for bringing the needle into the body; Automatic needle insertion A61M5/20, A61M5/31525 take precedence
• CPC Class Codes: G16H 20/17 : delivered via infusion or injection
• CPC Class Codes: G16H 40/20 : for the management or administration of healthcare resources or facilities, e.g. managing hospital staff or surgery rooms

Abstract

An apparatus includes a container defining an internal region configured to contain multiple medicament delivery devices, such as, for example, pen injectors, auto-injectors, inhalers or the like. The container includes an electronic circuit system configured to output a first electronic output associated with a first medicament delivery device contained within the internal region when the first medicament delivery device is removed from the internal region of the container. The electronic circuit system is further configured to output a second electronic output associated with a second medicament delivery device contained within the internal region when the second medicament delivery device is removed from the internal region of the container. The second electronic output is different than the first electronic output. At least one of the first electronic output or the second electronic output is associated with a use instruction.

Claims

1. An apparatus, comprising:

a container defining an internal region configured to contain at least a portion of a medicament delivery device, the container including an electronic circuit system including a switch, the electronic circuit system configured to receive an input from at least one of a microphone or an electronic visual display, the electronic circuit system configured to output a first electronic output associated with the input, the electronic circuit system configured to output a second electronic output associated with the medicament delivery device when the switch is moved from a first state to a second state, the container including a mounting portion configured to be coupled to a structure such that the electronic circuit system is operably coupled to a power source associated with the structure; and

a movable member configured to be movably coupled to the container, the movable member configured to maintain the portion of the medicament delivery device within the internal region, a portion of the movable member configured to move the switch from the first state to the second state when the movable member is moved relative to the container.

2. The apparatus of claim 1, wherein at least one of the first electronic output or the second electronic output is associated with at least one of an identification of the medicament delivery device, an identification of a physical condition or an instruction for using the medicament delivery device.

3. The apparatus of claim 1, wherein at least one of the first electronic output or the second electronic output is a wireless communications signal.

4. The apparatus of claim 1, further comprising;

the electronic visual display, at least one of the first electronic output or the second electronic output includes a visual output produced by the electronic visual display.

5. The apparatus of claim 1, wherein at least one of the first electronic output or the second electronic output includes a recorded speech output.

6. The apparatus of claim 1, wherein the switch is a first switch, the electronic circuit system includes a second switch, the apparatus further comprising:

a retainer configured to retain the medicament delivery device within the internal region, the electronic circuit system includes a second switch associated with the retainer, a portion of the retainer configured to move the second switch between a first state and a second state when the retainer is moved relative to the container, the electronic circuit system configured to output a third electronic output when the second switch moves between its first state and its second state.

7. The apparatus of claim 1, wherein:

the medicament delivery device includes a label configured to output a signal configured to be received by the electronic circuit system, the signal associated with at least one of a location of the medicament delivery device, a contents of the medicament delivery device, an expiration date of the medicament delivery device, a dosage of the medicament delivery device or a use instruction associated with the medicament delivery device; and

at least one of the first electronic output or the second electronic output is associated with the signal received by the electronic circuit system.

8. The apparatus of claim 1, further comprising:

the electronic visual display coupled to the movable member, at least one of the first electronic output or the second electronic output includes a visual output produced by the electronic visual display.

9. An apparatus, comprising:

a container defining an internal region configured to contain at least a portion of a medicament delivery device, the container including a mounting portion;

a movable member configured to be movably coupled to the container, the movable member configured to limit movement of the medicament delivery device; and

an electronic circuit system coupled to the container, the mounting portion of the container configured to be coupled to a structure such that the electronic circuit system is operably coupled to a power source associated with the structure, the electronic circuit system including an electronic visual display and a speaker, the electronic circuit system configured to produce a first output via at least one of the electronic visual display or the speaker, the electronic circuit system configured to produce a second output in response to an input received from at least one of a microphone or the electronic visual display, the electronic circuit system configured to produce a third output when the movable member is moved.

10. The apparatus of claim 9, wherein the electronic visual display is coupled to the movable member.

11. The apparatus of claim 9, wherein at least one of the second output or the third output includes a wireless communications signal.

12. The apparatus of claim 9, wherein at least one of the first output, the second output or the third output includes a recorded speech output.

13. The apparatus of claim 9, wherein:

the electronic circuit system including a switch disposed on a printed circuit board, the electronic circuit system configured to produce the third output when the switch is moved from a first state to a second state; and

the movable member is configured to retain a portion of the medicament delivery device within the internal region, a portion of the movable member configured to engage a portion of the printed circuit board to move the switch from the first state to the second state when the movable member is moved relative to the container.

14. The apparatus of claim 9, further comprising:

a battery disposed within the container, the battery configured to be operably coupled to the electronic circuit system.

15. An apparatus, comprising:

a container defining an internal region configured to contain at least a portion of a medicament delivery device, the container including a mounting portion;

a movable member configured to be movably coupled to the container, the movable member configured to limit movement of the medicament delivery device; and

an electronic circuit system coupled to the container, the mounting portion of the container configured to be coupled to a structure such that the electronic circuit system is operably coupled to a power source associated with the structure, the electronic circuit system including a switch and an electronic visual display, the electronic circuit system configured to receive an input from at least one of a microphone or the electronic visual display, the electronic circuit system configured to produce a first electronic output associated with the input, the electronic circuit system configured to produce a second electronic output when the switch is moved from a first state to a second state,

a portion of the movable member configured to move the switch from the first state to the second state when the movable member is moved relative to the container.

16. The apparatus of claim 15, wherein the electronic visual display is coupled to the movable member.

17. The apparatus of claim 15, further comprising:

a battery disposed within the container, the battery configured to be operably coupled to the electronic circuit system.