Lumen clearing valve for glaucoma drainage device

• US 8,545,431 B2
• Filed: 10/30/2009
• Issued: 10/01/2013
• Est. Priority Date: 09/21/2009
• Status: Active Grant

• Current Assignee: Alcon Incorporated
• Original Assignee: Alcon Research Limited (Nestle SA)
• Inventors: Rickard, Matthew J. A.
• Primary Examiner(s): Wiest, Philip R
• Application Number:
  US12/609,043
• Publication Number:
  US 20110071456A1
• Time in Patent Office: 1,432 Days
• Field of Search: 604 8- 10, 604/294
• US Class Current: 604/9
• CPC Class Codes: A61B 3/16 for measuring intraocular pressure, e.g. tonometers
• CPC Class Codes: A61B 5/6821 Eye
• CPC Class Codes: A61F 9/00781 Apparatus for modifying intraocular pressure, e.g. for glaucoma treatment drainage implants in general A61M27/002

Abstract

A glaucoma drainage device has a housing with an open outlet end. A tube is in fluid communication with the housing. An actuator is located in the housing. An actuation arm is located at least partially in the housing and is coupled to the actuator. A tapered arm is rigidly coupled to the actuation arm. A needle head is located opposite the tapered arm. A tapered end of the tapered arm is located at least partially in the tube. When the tapered arm is moved, it can clear an obstruction from the tube. When the needle head is moved, it can disperse aqueous or clear fibers from the drainage location.

Claims

1. A glaucoma drainage device comprising:

a housing with an open outlet end;

a tube in fluid communication with the housing;

a continuous lumen extending through the tube and the housing;

an actuator located in the housing;

an actuation arm located at least partially in the housing, the actuation arm coupled to the actuator; and

a tapered arm rigidly coupled to the actuation arm, a tapered end of the tapered arm located at least partially in the lumen.

2. The glaucoma drainage device of claim 1 wherein when the actuator moves the actuation arm and tapered arm, the tapered arm moves within the tube thereby clearing the tube.

3. The glaucoma drainage device of claim 1 wherein the tapered arm partially obstructs the lumen thereby restricting fluid flow through the tube.

4. The glaucoma drainage device of claim 1 wherein a first end of the tube is located in an anterior chamber of an eye and the outlet end of the housing is located in a subconjunctival space of the eye.

5. The glaucoma drainage device of claim 1 further comprising:

drainage holes located on the outlet end of the housing.

6. The glaucoma drainage device of claim 1 further comprising:

a needle head connecting the actuation arm to the tapered arm, the needle head located opposite the tapered end of the tapered arm.

7. The glaucoma drainage device of claim 6 wherein the actuator moves the needle head in a drainage location to clear fibers from the drainage location.

8. The glaucoma drainage device of claim 7 wherein the drainage location is a bleb.

9. The glaucoma drainage device of claim 6 wherein the actuator moves the needle head in a drainage location to disperse aqueous in the drainage location.

10. The glaucoma drainage device of claim 1 wherein the housing, the tube, the actuator, the actuation arm, and the tapered arm are located on or embedded in a substrate.

11. The glaucoma drainage device of claim 1 further comprising:

a first pressure sensor located in fluid communication with an anterior chamber of an eye; and

a second pressure sensor located in the vicinity of the outlet end of the housing;

wherein a difference between readings from the first pressure sensor and the second pressure sensor approximates a pressure differential between the anterior chamber and the drainage location.

12. The glaucoma drainage device of claim 11 further comprising:

a controller configured to control a position of the tapered arm based on the readings from the first pressure sensor and the second pressure sensor.

13. The glaucoma drainage device of claim 12 wherein a substantially constant pressure differential is maintained by controlling the position of the tapered arm.

14. The glaucoma drainage device of claim 13 wherein the pressure differential is adjusted by controlling the position of the tapered arm.

15. The glaucoma drainage device of claim 1 further comprising;

a first pressure sensor located in fluid communication with an anterior chamber of an eye; and

a remote pressure sensor located remotely from the first pressure sensor such that the remote pressure sensor measures or approximates atmospheric pressure

wherein a difference between readings from the first pressure sensor and the remote pressure sensor approximates intraocular pressure.

16. The glaucoma drainage device of claim 15 wherein the remote pressure sensor is located in a subconjunctival space of the eye.

17. The glaucoma drainage device of claim 15 further comprising:

a barrier that separates the first pressure sensor from the remote pressure sensor.

18. The glaucoma drainage device of claim 15 further comprising:

a controller configured to control a position of the tapered arm based on the readings from the first pressure sensor and the remote pressure sensor.

19. The glaucoma drainage device of claim 18 wherein a substantially constant intraocular pressure is maintained in the eye by controlling the position of the tapered arm.

20. The glaucoma drainage device of claim 18 wherein a substantially constant intraocular pressure drop is maintained by controlling the position of the tapered arm.

21. The glaucoma drainage device of claim 15 further comprising:

a second tube with a first end located in the anterior chamber and a second and located outside the anterior chamber; and

a plug located in the second end of the second tube, the plug having the first pressure sensor on one side of the plug and the remote pressure sensor on the other side of the plug.

22. The glaucoma drainage device of claim 1 further comprising:

a first pressure sensor located in a drainage location; and

a remote pressure sensor located remotely from the first pressure sensor such that the remote pressure sensor measures or approximates atmospheric pressure

wherein a difference between readings from the first pressure sensor and the remote pressure sensor approximates pressure in the drainage location.

23. The glaucoma drainage device of claim 22 further comprising:

a barrier that separates the first pressure sensor from the remote pressure sensor.

24. The glaucoma drainage device of claim 22 further comprising:

a controller configured to control a position of the tapered arm based on the readings from the first pressure sensor and the remote pressure sensor.

25. The glaucoma drainage device of claim 24 wherein a substantially constant pressure is maintained in the drainage location by controlling the position of the tapered arm.

26. The glaucoma drainage device of claim 24 wherein the pressure in the drainage location is adjusted by controlling the position of the tapered arm.