Injection device

• US 8,545,478 B2
• Filed: 01/05/2010
• Issued: 10/01/2013
• Est. Priority Date: 11/25/2002
• Status: Active Grant

• Current Assignee: Boston Scientific Scimed, Inc. (Boston Scientific Corporation)
• Original Assignee: Boston Scientific Scimed, Inc. (Boston Scientific Corporation)
• Inventors: Gough, Edward J., Stein, Alan
• Primary Examiner(s): BOUCHELLE, LAURA A
• Application Number:
  US12/652,148
• Publication Number:
  US 20100174162A1
• Time in Patent Office: 1,365 Days
• Field of Search: 604/20, 604/21, 604/506, 604/514, 604/516, 604/164.01, 604/165.01, 600/342, 600/175
• US Class Current: 604/516
• CPC Class Codes: A61B 17/00491 Surgical glue applicators surgical adhesives A61L24/00; two-component delivery syringes A61M5/19
• CPC Class Codes: A61B 2017/00269 endoscopic mucosal resection EMR
• CPC Class Codes: A61B 5/14546 for measuring analytes not otherwise provided for, e.g. ions, cytochromes
• CPC Class Codes: A61B 5/1459 invasive, e.g. introduced into the body by a catheter A61B5/1464 takes precedence
• CPC Class Codes: A61B 5/6848 Needles
• CPC Class Codes: A61M 2025/0089 Single injection needle protruding axially, i.e. along the longitudinal axis of the catheter, from the distal tip
• CPC Class Codes: A61M 25/0084 being one or more injection needles

Abstract

An injection device for use with tissue of a mammalian body comprising a first tubular member and a second tubular member slidably disposed in the first tubular member. The first and second tubular members have respective proximal and distal extremities. The distal extremity of the second tubular member is provided with a needle that is extendable from the distal extremity of the first tubular member. The proximal extremity of the second tubular member is lockable relative to the proximal extremity of the first tubular member. The second tubular member has a column strength when locked within the first tubular member for limiting retraction of the second tubular member relative to the first tubular member during puncture of the tissue by the needle.

Claims

1. A method for treating tissue in a wall forming a gastrointestinal tract of a mammalian body with a needle having proximal and distal extremities and at least one optical element extending in a passageway from the proximal extremity to the distal extremity of the needle comprising:

(a) inserting the distal extremity of the needle into the tissue;

(b) determining the type of tissue into which the distal end of the needle is disposed with the at least one optical element; and

(c) forming an implant in said wall by injecting an injectable material into said wall after determining the type of tissue into which the distal end of the needle is disposed.

2. The method of claim 1 wherein the determining step includes interrogating the tissue with the at least one optical element to detect the presence of myoglobin or hemoglobin.

3. The method of claim 1 wherein the determining step includes interrogating the tissue with the at least one optical element to determine the amount of oxygen saturation in the tissue.

4. The method of claim 1 wherein the determining step includes supplying light to the at least one optical element and thus the tissue and monitoring the light reflected back by the tissue.

5. The method of claim 1, wherein the type of is tissue is selected from a mucosal layer, a submucosal layer, a circular muscle layer and a longitudinal muscle layer.

6. The method of claim 1, wherein the type of is tissue is a submucosal layer.

7. The method of claim 1, wherein said injectable material comprises a biocompatible polymer and a biocompatible solvent.

8. The method of claim 7, wherein said injectable material comprises from 2.5 to 8.0 weight percent of said biocompatible polymer and from 52 to 87.5 weight percent of said biocompatible solvent.

9. The method of claim 8, wherein said injectable material further comprises from 10 to 40 weight percent of a biocompatible contrast agent.

10. The method of claim 7, wherein said biocompatible polymer comprises a hydrogel.

11. The method of claim 7, wherein said biocompatible polymer comprises an ethylene vinyl alcohol copolymer.

12. The method of claim 1, comprising making multiple injections at multiple wall sites to create a pattern of implants within the wall.