Analyte measurment method and system

• US 8,545,693 B2
• Filed: 09/03/2010
• Issued: 10/01/2013
• Est. Priority Date: 09/29/2009
• Status: Active Grant

• Current Assignee: Cilag Gmbh International (Johnson & Johnson)
• Original Assignee: LifeScan Scotland Limited (Johnson & Johnson)
• Inventors: McColl, David, Craggs, Adam, MacKintosh, Stephen, Blythe, Steve, Cardosi, Marco
• Primary Examiner(s): Van, Luan
• Assistant Examiner(s): ROSENWALD, STEVEN ERIC
• Application Number:
  US12/875,887
• Publication Number:
  US 20110073494A1
• Time in Patent Office: 1,124 Days
• Field of Search: 205/777.5, 204/400, 20440301-40304
• US Class Current: 205/777.5
• CPC Class Codes: G01N 27/3271 Amperometric enzyme electrodes for analytes in body fluids, e.g. glucose in blood amperometry per se G01N27/49; aspects concerning the enzyme reagent C12Q1/001
• CPC Class Codes: G01N 27/3274 Corrective measures, e.g. error detection, compensation for temperature or hematocrit, calibration coding of calibration information G01N33/48771

Abstract

Described and illustrated herein are systems and exemplary methods of operating a multianalyte measurement system having a meter and a test strip. In one embodiment, the method may be achieved by applying a test voltage between a reference electrode and a first working electrode; measuring a first test current, a second test current and a third test current at the working electrode with the meter after a blood sample containing an analyte is applied to the test strip; estimating a hematocrit-corrected analyte concentration from the first, second and third test currents; and displaying the hematocrit-corrected analyte concentration.

Claims

1. A method for determining a glucose concentration measurable with a system having a test strip and a meter, the method comprising:

applying a test voltage between a reference electrode and a working electrode coated with a reagent layer disposed on a matrix layer having a mediator;

measuring a first test current, a second test current and a third test current at the working electrode with the meter after a blood sample containing an analyte is applied to the test strip to physically transform the analyte into an enzymatic by-product;

determining a glucose concentration from the first, second and third test currents, in which the glucose concentration comprises a value obtained with the following;

2. The method of claim 1, in which the threshold value of the first test current comprises from about 5 microamperes to about 7 microamperes.

3. The method of claim 1, in which the power term comprises a value from about one to about four.