Human milk compositions and methods of making and using same

• US 8,545,920 B2
• Filed: 11/29/2007
• Issued: 10/01/2013
• Est. Priority Date: 11/29/2006
• Status: Active Grant

• Current Assignee: Prolacta Bioscience Inc.
• Original Assignee: Prolacta Bioscience Inc.
• Inventors: Medo, Elena M., Lee, Martin L., Rechtman, David J., Fournell, Joseph
• Primary Examiner(s): Tarazano, D. Lawrence
• Assistant Examiner(s): Anderson, Jerry W
• Application Number:
  US11/947,580
• Publication Number:
  US 20080124430A1
• Time in Patent Office: 2,133 Days
• Field of Search: 426/74, 426/580
• US Class Current: 426/580
• CPC Class Codes: A23C 9/206 Colostrum; Human milk
• CPC Class Codes: A23L 2/52 Adding ingredients adding preservatives A23L2/44
• CPC Class Codes: A23L 2/66 Proteins
• CPC Class Codes: A23L 33/10 using additives addition of substantially indigestible substances A23L33/21
• CPC Class Codes: A23L 33/15 Vitamins
• CPC Class Codes: A23L 33/16 Inorganic salts, minerals or trace elements
• CPC Class Codes: A23L 33/19 Dairy proteins
• CPC Class Codes: A23L 33/40 Complete food formulations for specific consumer groups or specific purposes, e.g. infant formula

Abstract

The disclosure features human milk fortifier compositions, standardized human milk, and methods of making and using same. In one embodiment, a pasteurized human milk composition includes a human protein constituent of about 35-85 mg/mL; a human fat constituent of about 60-110 mg/mL; and a human carbohydrate constituent of about 60-140 mg/mL.

Claims

1. A pasteurized human milk composition comprising:

a human protein constituent of about 55-95 mg/ml;

a human fat constituent of about 85-95 mg/mL; and

a human carbohydrate constituent of about 70-120 mg/mL.

2. The composition of claim 1, wherein the carbohydrate constituent comprises lactose.

3. The composition of claim 1, further comprising one or more constituents selected from the group consisting of:

calcium, chloride, copper, iron, magnesium, manganese, phosphorus, potassium, sodium, and zinc.

4. The composition of claim 1, comprising:

calcium concentration of about 4.0-5.5 mg/mL;

chloride concentration of about 0.35-0.95 mg/mL;

copper concentration of about 0.0005-0.0021 mg/mL;

iron concentration of about 0.001-0.007 mg/mL;

magnesium concentration of about 0.180-0.292 mg/mL;

manganese concentration of about 0.010-0.092 micrograms/mL;

phosphorus concentration of about 2.00-3.05 mg/mL;

potassium concentration of about 1.90-2.18 mg/mL;

sodium concentration of about 0.75-0.96 mg/mL; and

zinc concentration of about 0.0200-0.0369 mg/mL.

5. The composition of claim 1, comprising:

calcium concentration of about 2.00-2.90 mg/mL;

chloride concentration of about 0.175-0.475 mg/mL;

copper concentration of about 0.00025-0.001 mg/mL;

iron concentration of about 0.0005-0.0025 mg/mL;

magnesium concentration of about 0.090-0.170 mg/mL;

manganese concentration of about 0.005-0.046 micrograms/mL;

phosphorus concentration of about 1.00-1.50 mg/mL;

potassium concentration of about 0.95-1.41 mg/mL;

sodium concentration of about 0.375-0.608 mg/mL; and

zinc concentration of about 0.010-0.0198 mg/mL.