Implantable biosensor with automatic calibration
First Claim
1. Self-calibrating disposable biosensor comprising an electronic part and an electrochemical part, wherein the electrochemical part comprisesa needle having an external surface configured to contact living tissue, said needle having in its interior a microfluidic circuit (8, 9) for the circulation of at least one calibration fluid, andtwo or three electrodes (1, 2, 3) arranged on the external surface of the needle, one of the electrodes being a working electrode (1), said working electrode comprising porous bio-chemical sensing materials (30-32) configured to contact living tissue after implantation, andmeans for fluid communication (4) of the microfluidic circuit (8,9) for the calibration fluid which is in the interior of said needle with the layers (29-32) of the working electrode on the external surface of the needle.
0 Assignments
0 Petitions
Accused Products
Abstract
Implantable self-calibrating biosensor Subcutaneously or intracorporeally implantable biosensor, characterized by a closed microfluidic circuit with calibrating fluids, which communicates by a backward micro-dialysis logic with the exterior of said circuit, an open and in contact with the tissues and the interstitial fluid working electrode, for its self-calibration. One or more working electrodes may be positioned inside openable boxes from EAP, and be opened for the duration of the measurement and closed immediately after, succeeding one another in the measurement, as their sensitivity is diminished.
23 Citations
12 Claims
-
1. Self-calibrating disposable biosensor comprising an electronic part and an electrochemical part, wherein the electrochemical part comprises
a needle having an external surface configured to contact living tissue, said needle having in its interior a microfluidic circuit (8, 9) for the circulation of at least one calibration fluid, and two or three electrodes (1, 2, 3) arranged on the external surface of the needle, one of the electrodes being a working electrode (1), said working electrode comprising porous bio-chemical sensing materials (30-32) configured to contact living tissue after implantation, and means for fluid communication (4) of the microfluidic circuit (8,9) for the calibration fluid which is in the interior of said needle with the layers (29-32) of the working electrode on the external surface of the needle.
Specification