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Devices and methods for predicting and preventing restenosis

  • US 8,548,571 B2
  • Filed: 12/08/2010
  • Issued: 10/01/2013
  • Est. Priority Date: 12/08/2009
  • Status: Active Grant
First Claim
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1. A device for determining an enhanced risk of restenosis in an arterial tissue, the device comprising:

  • an imaging catheter having a sensor configured to image a portion of an artery;

    a processor configured to receive images of the artery from the sensor and to detect regions of hypercellularity in the artery by counting or estimating the amount of satellite-to-spindle shaped smooth muscle cells within stroma in the received images, and further configured to detect regions of either or both;

    lipid-rich tissue and inflammatory cells in the artery from the received images; and

    a display configured to display a modified view of the artery indicating hypercellularity and the one or both of lipid-rich tissue and inflammatory cells in the artery.

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