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Solid dispersions containing kinase inhibitors

  • US 8,557,995 B2
  • Filed: 06/07/2011
  • Issued: 10/15/2013
  • Est. Priority Date: 06/09/2010
  • Status: Expired due to Fees
First Claim
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1. A solid dispersion product comprising N-(4-{4-amino-7-[1-(2-hydroxyethyl)-1H-pyrazol-4-yl]thieno [3,2-c]pyridin-3-yl}phenyl)-N′

  • -(3-fluorophenyl)urea or a pharmaceutically acceptable salt thereof, at least one pharmaceutically acceptable water-soluble polymeric carrier, and at least one pharmaceutically acceptable surfactant, wherein the N-(4-{4-amino-7-[1-(2-hydroxyethyl)-1H-pyrazol-4-yl]thieno[3,2-c]pyridin-3-yl}phenyl)-N′

    -(3-fluorophenyl)urea is present in about 1% to about 40% by free base equivalent weight.

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