Liquid dispensing apparatus and methods

• US 8,561,604 B2
• Filed: 02/12/2007
• Issued: 10/22/2013
• Est. Priority Date: 04/05/1995
• Status: Expired due to Fees

• Current Assignee: Novartis Ag
• Original Assignee: Novartis Ag
• Inventors: Ivri, Yehuda, Wu, Cheng H.
• Primary Examiner(s): Yu, Justine
• Assistant Examiner(s): Stuart, Colin W
• Application Number:
  US11/674,089
• Publication Number:
  US 20070209659A1
• Time in Patent Office: 2,444 Days
• Field of Search: 128/200.16, 128/14, 128/18, 128/21, 128/24, 128/202.21, 128/203.12, 128/15, 128/26, 128/27
• US Class Current: 128/200.16
• CPC Class Codes: A61M 11/005 using ultrasonics spraying or atomising liquids using ultrasonic vibrations in general B05B17/06
• CPC Class Codes: A61M 15/0085 using ultrasonics spraying or atomising liquids using ultrasonic vibrations in general B05B17/06
• CPC Class Codes: A61M 15/009 using medicine packages with incorporated spraying means, e.g. aerosol cans pocket atomiser of the injector type A61M11/08
• CPC Class Codes: A61M 2016/0021 with a proportional output signal, e.g. from a thermistor
• CPC Class Codes: A61M 2016/0039 in the inspiratory circuit

Abstract

The invention provides methods and apparatus for nebulizing liquids. In one exemplary embodiment, an apparatus is provided which comprises a thin shell member having a front surface, a rear surface, and a plurality of apertures extending therebetween. The apertures are tapered to narrow from the rear surface to the front surface. A liquid supplier is further provided which delivers a predetermined unit volume of liquid to the rear surface. A vibrator vibrates the thin shell member to eject liquid droplets from the front surface of the thin shell member.

Claims

1. A method for aerosolizing a liquid, the method comprising:

providing an aerosolization device comprising an aerosol generator, an inhalation sensor, an acoustic chamber, and control circuitry, wherein the aerosol generator comprises a plate having a plurality of apertures and a vibratable element that is mechanically linked to the plate, wherein the vibratable element is configured to vibrate the plate, wherein the plate is non-planar in geometry, and wherein the acoustic chamber is adapted to produce an audible signal that has an acoustic tone during inhalation;

sensing a user inhalation with the sensor based on the acoustic tone, wherein the acoustic tone is proportional to the inhalation;

transmitting an electrical signal indicating the inhalation to the control circuitry;

sending a signal from the control circuitry to vibrate the vibratable element only when the inhalation reaches a threshold amount; and

sending a second signal from the control circuitry to control a rate of liquid delivered to the vibratable element such that aerosolized liquid is produced at a rate corresponding to a rate of the inhalation.

2. A method as in claim 1, further comprising stopping vibration of the vibratable element when the inhalation falls below the threshold amount.

3. A method as in claim 1, wherein the inhalation is sensed by sensing air moving through at least a portion of the aerosolization device.

4. A method as in claim 1, wherein the vibratable element comprises a piezoelectric transducer, and further comprising sending an electrical signal from the control circuitry to the piezoelectric transducer to vibrate the plate.

9. A method as in claim 1, further comprising recording the acoustic tone to produce a record of a breathing pattern of the user.

5. An aerosolization device comprising:

a housing;

an aerosol generator operably coupled to the housing, wherein the aerosol generator comprises a plate having a plurality of apertures and a vibratable element that is mechanically linked to the plate, wherein the aerosol generator is adapted to aerosolize a liquid for delivery to a user, and wherein the plate is non-planar in geometry;

an acoustic chamber adapted to produce an audible signal that has an acoustic tone during inhalation;

an inhalation sensor that is configured to sense when the user inhales based on the acoustic tone, and to produce an electrical signal that is based on the acoustic tone that is proportional to the sensed inhalation;

control circuitry that is configured to actuate the aerosol generator when the electrical signal indicates that the inhalation has reached a threshold amount and to control a rate of liquid delivered to the vibratable element such that aerosolized liquid is produced at a rate corresponding to a rate of the sensed inhalation.

6. A device as in claim 5, wherein the control circuitry is further configured to stop actuation of the aerosol generator when the electrical signal indicates that the inhalation has fallen below the threshold amount.

7. A device as in claim 5, wherein the inhalation sensor is configured to sense air moving through at least a portion of the aerosolization device.

8. A device as in claim 5, wherein the vibratable element comprises a piezoelectric transducer.

10. A device as in claim 5, wherein the control circuitry is further adapted to record the acoustic tone to produce a record of a breathing pattern of the user.