Prevention of aortic valve fusion
First Claim
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1. A blood pump system, comprising:
- a blood pump having an inflow conduit for receiving blood from a left ventricle of a heart and an outflow conduit for returning blood to a circulatory system; and
a controller operably connected to the blood pump;
wherein the inflow conduit comprises a first sensor to detect an inflow conduit pressure that is substantially the same as left ventricular pressure,wherein the first sensor is adapted to send a signal regarding the inflow conduit pressure to the controller,wherein the outflow conduit comprises a second sensor to detect an outflow conduit pressure that is substantially the same as arterial pressure,wherein the second sensor is adapted to send a signal regarding the outflow conduit pressure to the controller, andwherein the controller is adapted to send a signal to the blood pump such that the speed of the blood pump is adjusted at a particular interval to increase left ventricular pressure as detected by the first sensor relative to arterial pressure as detected by the second sensor to open an aortic valve of the heart.
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Abstract
Materials and methods related to blood pump systems are described. These can be used in patients to, for example, monitor arterial pressure, measure blood flow, maintain left ventricular pressure within a particular range, avoid left ventricular collapse, prevent fusion of the aortic valve in a subject having a blood pump, and provide a means to wean a patient from a blood pump.
82 Citations
28 Claims
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1. A blood pump system, comprising:
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a blood pump having an inflow conduit for receiving blood from a left ventricle of a heart and an outflow conduit for returning blood to a circulatory system; and a controller operably connected to the blood pump; wherein the inflow conduit comprises a first sensor to detect an inflow conduit pressure that is substantially the same as left ventricular pressure, wherein the first sensor is adapted to send a signal regarding the inflow conduit pressure to the controller, wherein the outflow conduit comprises a second sensor to detect an outflow conduit pressure that is substantially the same as arterial pressure, wherein the second sensor is adapted to send a signal regarding the outflow conduit pressure to the controller, and wherein the controller is adapted to send a signal to the blood pump such that the speed of the blood pump is adjusted at a particular interval to increase left ventricular pressure as detected by the first sensor relative to arterial pressure as detected by the second sensor to open an aortic valve of the heart. - View Dependent Claims (2, 3, 4, 5, 6, 7, 8)
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9. A method for preventing aortic valve fusion in a subject having a blood pump system that bypasses the subject'"'"'s aortic valve, the blood pump system comprising a blood pump, wherein the method comprises:
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detecting left ventricular pressure via a sensor present at an inflow conduit of the blood pump system; detecting arterial pressure via a sensor present at an outflow conduit of the blood pump system; and adjusting the speed of the blood pump at a particular interval based on the detected left ventricular pressure and the detected arterial pressure such that left ventricular pressure is increased to open the aortic valve. - View Dependent Claims (10, 11, 12, 13, 14, 15, 16)
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17. A blood pump system, comprising:
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a blood pump having an inflow conduit for receiving blood from a left ventricle of a heart and an outflow conduit for returning blood to a circulatory system; and a controller operably connected to the blood pump, wherein the controller is configured to receive information sent from the blood pump for determining a pressure differential between the inflow conduit and the outflow conduit, and to send a signal to the blood pump to adjust the speed of the blood pump at a particular interval to adjust the pressure differential to cause an aortic valve of the heart to open. - View Dependent Claims (18, 19, 20, 21, 22)
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23. A method for controlling a blood pump configured to bypass blood flow across an aortic valve of a heart, comprising:
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receiving information from the blood pump; and sending a signal to the pump based on the received information, the signal causing the speed of the blood pump to be; adjusted at a particular interval such that a pressure differential across an inflow conduit and an outflow conduit of the blood pump is adjusted to open the aortic valve; and maintained at the adjusted speed for a predetermined length of time. - View Dependent Claims (24, 25, 26, 27, 28)
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Specification