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Methods and compositions for treatment of bone defects with placental cell populations

  • US 8,562,972 B2
  • Filed: 10/23/2007
  • Issued: 10/22/2013
  • Est. Priority Date: 10/23/2006
  • Status: Active Grant
First Claim
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1. A method for treating a bone defect in a subject, wherein said bone defect is an osteolytic lesion associated with multiple myeloma, bone cancer, or metastatic cancer characterized by bone metastases, comprising administering to a subject in need thereof an implantable or injectable composition comprising a population of placental stem cells, wherein said population is predominantly CD34

  • , CD10+, CD105+, and CD200+, and wherein said stem cells express HLA-G, thereby treating the bone defect in the subject.

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