Silver-containing wound care device

• US 8,563,447 B2
• Filed: 08/14/2003
• Issued: 10/22/2013
• Est. Priority Date: 08/14/2003
• Status: Active Grant

• Current Assignee: Milliken & Company
• Original Assignee: Milliken & Company
• Inventors: Canada, T. Andrew, Schuette, Robert L., Sturm, Raymond C., Wiencek, Kenneth M., Kreider, Jason L.
• Primary Examiner(s): Soroush, Ali
• Application Number:
  US10/640,918
• Publication Number:
  US 20050037680A1
• Time in Patent Office: 3,722 Days
• Field of Search: 428/376, 428/375, 442/123, 424/78.1, 427/125, 106/170.28
• US Class Current: 442/123
• CPC Class Codes: A61K 33/38 Silver; Compounds thereof
• CPC Class Codes: A61L 15/18 containing inorganic materials
• CPC Class Codes: A61L 15/44 Medicaments
• CPC Class Codes: A61L 15/46 Deodorants or malodour counteractants, e.g. to inhibit the formation of ammonia or bacteria
• CPC Class Codes: Y10T 442/20 Coated or impregnated woven, knit, or nonwoven fabric which is not [a] associated with another preformed layer or fiber layer or, [b] with respect to woven and knit, characterized, respectively, by a particular or differential weave or knit, wherein the coating or impregnation is neither a foamed material nor a free metal or alloy layer
• CPC Class Codes: Y10T 442/2525 Coating or impregnation functions biologically [e.g., insect repellent, antiseptic, insecticide, bactericide, etc.]

Abstract

Wound care devices having a topically applied silver-based antimicrobial finish are provided. The finish comprises at least one silver ion-containing compound and at least one binder compound. The finish may be applied to a target substrate, such as a fiber, fabric, film, foam, hydrogel, or hydrocolloid to provide a single layer antimicrobial wound care device. Alternatively, a silver-containing layer may be combined with one or more additional layers of target substrate to provide a composite antimicrobial wound care device. The device may also contain an odor-absorbing component capable of reducing or eliminating odors that are inherently associated with infectious wounds. Also provided is a method for making the wound care device and a composition of matter comprising the silver-based antimicrobial finish.

Claims

1. A substrate having a surface, at least a portion of which is coated with a non-electrically conductive finish, wherein said finish consists essentially of:

(a) 0.01 to 60 weight percent of at least one compound delivering silver ions, and

(b) an aqueous polyurethane binder system;

wherein the ratio of said at least one compound delivering silver ions to said binder system is in the range of 1;

1 to 1.35;

1 and wherein the coated substrate is an absorbent fabric.

2. The substrate of claim 1, wherein said at least one compound delivering silver ions is a silver ion exchange material.

3. The substrate of claim 2, wherein the silver ion exchange material is selected from silver zirconium phosphate compounds, silver calcium phosphate compounds, silver zeolite compounds, silver glass compounds, and any combinations thereof.

4. The substrate of claim 3, wherein said silver ion exchange material is a silver zirconium phosphate compound.

5. The substrate of claim 1, wherein said substrate is a knit fabric.

6. The substrate of claim 1, wherein said substrate exhibits antimicrobial properties.