Integrated multi-mode mammography/tomosynthesis x-ray system and method

• US 8,565,374 B2
• Filed: 05/02/2012
• Issued: 10/22/2013
• Est. Priority Date: 11/26/2004
• Status: Active Grant

• Current Assignee: Hologic Incorporated
• Original Assignee: Hologic Incorporated
• Inventors: Defreitas, Kenneth, Farbizio, Tom, Ren, Baori, Ruth, Chris, Shaw, Ian, Smith, Andrew, Stein, Jay
• Primary Examiner(s): Midkiff, Anastasia
• Application Number:
  US13/462,342
• Publication Number:
  US 20120219111A1
• Time in Patent Office: 538 Days
• Field of Search: 378 21- 27, 378/37, 378/62, 378114-116, 378/210
• US Class Current: 378/37
• CPC Class Codes: A61B 6/025 Tomosynthesis
• CPC Class Codes: A61B 6/107 Protection against radiation, e.g. shielding
• CPC Class Codes: A61B 6/4291 the detector being combined with a grid or grating
• CPC Class Codes: A61B 6/4417 related to combined acquisition of different diagnostic modalities
• CPC Class Codes: A61B 6/4452 the source unit and the detector unit being able to move relative to each other
• CPC Class Codes: A61B 6/482 involving multiple energy imaging
• CPC Class Codes: A61B 6/502 for diagnosis of breast, i.e. mammography
• CPC Class Codes: G06T 2207/30068 Mammography; Breast

Abstract

A system for multi-mode breast x-ray imaging which comprises a compression arm assembly for compressing and immobilizing a breast for x-ray imaging, an x-ray tube assembly, and an x-ray image receptor is provided. The system is configured for a plurality of imaging protocols and modes.

Claims

1. A system for multi-mode breast x-ray imaging, comprising:

a compression arm assembly for compressing and immobilizing a patient'"'"'s breast for x-ray imaging;

an x-ray assembly; and

an x-ray image receptor;

wherein said compression arm assembly, said x-ray tube assembly and said x-ray image receptor are configured for movement to accommodate a plurality of imaging protocols and modes, and are angled relative to each other for different ones of said imaging protocols and modes; and

wherein said system is configured to deliver substantially lower x-ray dose to the patient'"'"'s breast in taking a projection x-ray image of the breast when operating in a first one or said imaging modes than when operating in a second one of said imaging modes.

2. The system of claim 1 in which the system is configured to take plural tomosynthesis projection images of the breast during a single immobilization of the breast when operating in the first mode and a mammogram image of the breast when operating in the second mode, and wherein the total x-ray dose to the breast for the tomosynthesis projection images taken in the single breast immobilization is approximately the same as the x-ray dose for the mammogram taken in the second mode of operation.

3. The system of claim 1 in which the system is configured to take plural tomosynthesis projection images of the breast during a single immobilization of the breast when operating in the first mode and a mammogram image of the breast when operating in the second mode, and wherein the total x-ray dose to the breast for the tomosynthesis projection images taken in the single immobilization is no more than approximately three times the x-ray dose for the mammogram taken in the second mode of operation.

4. An x-ray breast imaging system comprising:

an x-ray source, an x-ray imaging receptor, and a breast immobilizer between the source and receptor;

said source being configured to selectively emit an imaging x-ray beam that passes through the breast immobilizer and impinges on the receptor, and the receptor being configured to generate a projection x-ray image in response to the imaging beam;

said system being configured to operate in a first imaging mode in which the system takes a first projection x-ray image at a selected first position of the x-ray source relative to the breast immobilizer and in a second imaging mode in which the system takes a plural projection images each taken at a different position of the source relative to the breast immobilizer;

wherein the x-ray dose for one of the plural projection images is substantially lower than for said first projection image.

5. The system of claim 4 in which the total x-ray dose for the plural images is approximately one to three times the x-ray dose for said first image.

6. The system of claim 4 in which the total x-ray dose for the plural images is approximately the same as the x-ray dose for the first image.

7. The system of claim 4 in which the first image is a mammogram and the plural images are tomosynthesis projection images.

9. The system of claim 4 in which the plural images comprise between 11 and 21 tomosynthesis projection images.

10. The system of claim 4 in which the system is configured to take said plural images during a continuous motion of the source relative to the breast immobilizer.

11. The system of claim 10 in which the system is configured to take said plural images while the imaging beam continuously impinges on the breast immobilizer.

12. The system of claim 10 in which the system is configured to take said plural images while the imaging beam intermittently impinges on the breast immobilizer.

13. The system of claim 12 in which the system is configured to take said plural images in the course of an intermittent motion of the source relative to the breast immobilizer.

14. The system of claim 4 comprising a gantry supporting the source, receptor and immobilizer, and a data acquisition work station coupled with the gantry and configured to control the gantry and to receive and process said images.

15. The system of claim 4 in which the immobilizer comprises a breast platform having a front for facing a patient and a width, and a compression paddle that is smaller in width than the platform and is mounted for selective motion along the platform width.

16. The system of claim 4 including a paddle support configured to move the paddle along the platform width.

17. The system of claim 4 in which the support is motorized to move the paddle along the platform width.

18. The system of claim 4 in which the support comprises manually operated devices for moving the paddle along the platform width.

19. The system of claim 4 in which said system is configured to set a collimation of the imaging beam matching a size of the paddle.

20. The system of claim 19 in which the system is configured to automatically set the collimation of the imaging beam to match the size of the paddle.

8. The system of claim in which the plural images comprise at least 11 tomosynthesis projection images.

21. A multi-mode breast x-ray imaging system comprising:

an x-ray source, an x-ray imaging receptor, and a breast immobilizer between the source and receptor;

said system being configured to change, in response to operator selection, from one to the other of (a) a standard mammography mode in which the source, immobilizer and receptor are mounted for rotation as a unit, and (b) a tomosynthesis mode in which the source and receptor are mounted for rotation relative to the immobilizer; and

said system being further configured to take a standard mammogram in said mammogram mode but to take plural tomosynthesis projection images in said tomosynthesis mode during a single immobilization of a patient'"'"'s breast.

22. The system of claim 21 including an anti-scatter grid between the immobilizer and the receptor.

23. The system of claim 21 in which the system is configured to operate in the absence of an anti-scatter grid between the breast and the imaging receptor in at least one of said mammogram mode and tomosynthesis mode.

24. The system of claim 21 in which the x-ray dose for taking plural projection images in a single immobilization in the tomosynthesis mode is approximately one to three times the x-ray dose for taking a mammogram in said mammogram mode.